Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Michael C. Ayers"'
Publikováno v:
Toxicology Reports, Vol 8, Iss , Pp 38-43 (2021)
Following chemical spill disasters, it is important to estimate the effects of spilled chemicals on humans and the environment. Here we analyzed the toxicological effects of the coal cleaning chemical, 4-methylcyclohexane methanol (MCHM), which was s
Externí odkaz:
https://doaj.org/article/15b1af2d32f849a58766fd91ba0fbb28
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 12, Pp 4665-4678 (2020)
Externí odkaz:
https://doaj.org/article/f95933ca7f2244e7873da075bf3d5d1e
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 2, Pp 607-619 (2018)
Cellular metabolism can change the potency of a chemical’s tumorigenicity. 4-nitroquinoline-1-oxide (4NQO) is a tumorigenic drug widely used on animal models for cancer research. Polymorphisms of the transcription factor Yrr1 confer different level
Externí odkaz:
https://doaj.org/article/77488bc29d8c4d4d9428cf0f47ec94fa
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 5, p 1894 (2020)
The Mediator is composed of multiple subunits conserved from yeast to humans and plays a central role in transcription. The tail components are not required for basal transcription but are required for responses to different stresses. While some stre
Externí odkaz:
https://doaj.org/article/df894f871ae34a5d94735c39d55a686c
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 12, Pp 4665-4678 (2020)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
In 2014, the coal cleaning chemical 4-methylcyclohexane methanol (MCHM) spilled into the water supply for 300,000 West Virginians. Initial toxicology tests showed relatively mild results, but the underlying effects on cellular biology were underexplo
In 2014, the coal cleaning chemical 4-methylcyclohexane methanol (MCHM) spilled into the water supply for 300,000 West Virginians. Initial toxicology tests showed relatively mild results, but the underlying effects on cellular biology were underexplo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a243f65a892111ea0b21fe55a937f079
https://doi.org/10.1101/2020.08.17.253799
https://doi.org/10.1101/2020.08.17.253799
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 8, Iss, Pp 38-43 (2021)
Toxicology Reports, Vol 8, Iss, Pp 38-43 (2021)
Graphical abstract
Highlights • MCHM reduces cell viability in vitro that can be partially rescued with antioxidants. • MCHM causes immediate and reversible non-responsiveness in Xenopus embryos. • When reared in MCHM, Xenopus embryos are
Highlights • MCHM reduces cell viability in vitro that can be partially rescued with antioxidants. • MCHM causes immediate and reversible non-responsiveness in Xenopus embryos. • When reared in MCHM, Xenopus embryos are
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 5, p 1894 (2020)
Volume 21
Issue 5
International Journal of Molecular Sciences, Vol 21, Iss 5, p 1894 (2020)
Volume 21
Issue 5
The Mediator is composed of multiple subunits conserved from yeast to humans and plays a central role in transcription. The tail components are not required for basal transcription but are required for responses to different stresses. While some stre
Publikováno v:
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 8, Iss 2, Pp 607-619 (2018)
G3: Genes, Genomes, Genetics, Vol 8, Iss 2, Pp 607-619 (2018)
Cellular metabolism can change the potency of a chemical’s tumorigenicity. 4-nitroquinoline-1-oxide (4NQO) is a tumorigenic drug widely used on animal models for cancer research. Polymorphisms of the transcription factor Yrr1 confer different level