Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Michael C W, Chan"'
Autor:
Rabeh El-Shesheny, John Franks, Ahmed Kandeil, Rebecca Badra, Jasmine Turner, Patrick Seiler, Bindumadhav M. Marathe, Trushar Jeevan, Lisa Kercher, Meng Hu, Yul Eum Sim, Kenrie P. Y. Hui, Michael C. W. Chan, Andrew J. Thompson, Pamela McKenzie, Elena A. Govorkova, Charles J. Russell, Peter Vogel, James C. Paulson, J. S. Malik Peiris, Robert G. Webster, Mohamed A. Ali, Ghazi Kayali, Richard J. Webby
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract In 2017, a novel influenza A virus (IAV) was isolated from an Egyptian fruit bat. In contrast to other bat influenza viruses, the virus was related to avian A(H9N2) viruses and was probably the result of a bird-to-bat transmission event. To
Externí odkaz:
https://doaj.org/article/0e383400a9d3481ebc14bb85730eae93
Autor:
Louisa L. Y. Chan, John M. Nicholls, J. S. Malik Peiris, Yu Lung Lau, Michael C. W. Chan, Renee W. Y. Chan
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background Neutrophil is of the most abundant number in human immune system. During acute influenza virus infection, neutrophils are already active in the early phase of inflammation - a time in which clinical biopsy or autopsy material is n
Externí odkaz:
https://doaj.org/article/b216354569e1480883256507ab06201b
Autor:
Alex W H Chin, Julie T S Chu, Mahen R A Perera, Kenrie P Y Hui, Hui-Ling Yen, Michael C W Chan, Malik Peiris, Leo L M Poon
Publikováno v:
The Lancet Microbe, Vol 1, Iss 1, Pp e10- (2020)
Externí odkaz:
https://doaj.org/article/d62e08a4145442008740226d5334d16a
Autor:
Li-Meng Yan, Sylvia P. N. Lau, Chek Meng Poh, Vera S. F. Chan, Michael C. W. Chan, Malik Peiris, Leo L. M. Poon
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Anti-galactose-α-1,3-galactose (anti-α-Gal) antibody is naturally expressed at a high level in humans. It constitutes about 1% of immunoglobulins found in human blood. Here, we designed a live attenuated influenza virus vaccine that can ge
Externí odkaz:
https://doaj.org/article/aac62f74ea6845b4ae0fd50f41bb6eae
Autor:
Meghan S. Vermillion, Rebecca L. Ursin, Denise I. T. Kuok, Landon G. vom Steeg, Nicholas Wohlgemuth, Olivia J. Hall, Ashley L. Fink, Eric Sasse, Andrew Nelson, Roland Ndeh, Sharon McGrath-Morrow, Wayne Mitzner, Michael C. W. Chan, Andrew Pekosz, Sabra L. Klein
Publikováno v:
Biology of Sex Differences, Vol 9, Iss 1, Pp 1-12 (2018)
Abstract Background Amphiregulin (AREG) is an epidermal growth factor that is a significant mediator of tissue repair at mucosal sites, including in the lungs during influenza A virus (IAV) infection. Previous research illustrates that males of repro
Externí odkaz:
https://doaj.org/article/4597e7cc17e9456eaaa7c5abe1b54238
Autor:
Renee W. Y. Chan, Louisa L. Y. Chan, Chris K. P. Mok, Jimmy Lai, Kin P. Tao, Adebimpe Obadan, Michael C. W. Chan, Daniel R. Perez, J. S. Malik Peiris, John M. Nicholls
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract H9N2 viruses are the most widespread influenza viruses in poultry in Asia. We evaluated the infection and tropism of human and avian H9 influenza virus in the human respiratory tract using ex vivo respiratory organ culture. H9 viruses infect
Externí odkaz:
https://doaj.org/article/a88fb802eb6d4c6d93934d1048fc8e5d
Autor:
Kenrie P. Y. Hui, John C. W. Ho, Man-chun Cheung, Ka-chun Ng, Rachel H. H. Ching, Ka-ling Lai, Tonia Tong Kam, Haogao Gu, Ko-Yung Sit, Michael K. Y. Hsin, Timmy W. K. Au, Leo L. M. Poon, Malik Peiris, John M. Nicholls, Michael C. W. Chan
Publikováno v:
Nature. 603:715-720
Autor:
Scott Krauss, Adam Rubrum, Mengting Zhang, Yvonne C. F. Su, John Franks, Philippe Noriel Q. Pascua, Gavin J. D. Smith, Hui-Ling Yen, Trushar Jeevan, Chung-Yi Wu, Jeremy C. Jones, Richard J. Webby, Yue Ji, Christina Kackos, Rhodri Harfoot, Yuqin Zhang, Michael C. W. Chan, Robert G. Webster, Jennifer DeBeauchamp, Udayan Joseph, Kristien Van Reeth, Jeri-Carol Crumpton, Lisa Kercher, Jayanthi Jayakumar, Wen Su, Malik Peiris, Stephan Pleschka, Huyen Trang Bui
Publikováno v:
Nature Microbiology. 6:1455-1465
Understanding the evolutionary adaptations that enable avian influenza viruses to transmit in mammalian hosts could allow better detection of zoonotic viruses with pandemic potential. We applied ancestral sequence reconstruction to gain viruses repre
Autor:
J. S. Malik Peiris, Daniel K.W. Chu, Michael C. W. Chan, Christine H T Bui, John M. Nicholls, Kenrie P Y Hui, Ka-Chun Ng, Richard J. Webby, Denise I. T. Kuok, Hin Wo Yeung
Publikováno v:
Emerging Infectious Diseases, Vol 27, Iss 10, Pp 2619-2627 (2021)
Emerging Infectious Diseases
Emerging Infectious Diseases
The numerous global outbreaks and continuous reassortments of highly pathogenic avian influenza (HPAI) A(H5N6/H5N8) clade 2.3.4.4 viruses in birds pose a major risk to the public health. We investigated the tropism and innate host responses of 5 rece
Publikováno v:
Inorganic chemistry. 61(48)
A series of conformationally rigid (Zn-salphen)