Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Michael C Lorenz"'
Autor:
Pedro Miramón, Michael C Lorenz
Publikováno v:
PLoS Pathogens, Vol 13, Iss 2, p e1006144 (2017)
Externí odkaz:
https://doaj.org/article/0f8697893f864fe69097d726ecf831ff
Autor:
Slavena Vylkova, Michael C Lorenz
Publikováno v:
PLoS Pathogens, Vol 10, Iss 3, p e1003995 (2014)
Candida albicans, the most important fungal pathogen of humans, has a unique interaction with macrophages in which phagocytosis induces a switch from the yeast to hyphal form, allowing it to escape by rupturing the immune cell. While a variety of fac
Externí odkaz:
https://doaj.org/article/c8ed2c7fae8340e68f2e34cfd50365be
Autor:
Michael C. Lorenz
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT A recent study in mBio reports the construction and preliminary screening of a library containing mutants of 99 of the 119 predicted protein kinases in Candida albicans (the majority of the remaining 20 are probably essential) (J. Kramara, M
Externí odkaz:
https://doaj.org/article/eb2dfc30c7884a0eb435b755f0c6a392
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e96203 (2014)
Macrophages and neutrophils generate a potent burst of reactive oxygen and nitrogen species as a key aspect of the antimicrobial response. While most successful pathogens, including the fungus Candida albicans, encode enzymes for the detoxification o
Externí odkaz:
https://doaj.org/article/ee33c24799444d598463e15b432650f3
Publikováno v:
PLoS Pathogens, Vol 9, Iss 11, p e1003741 (2013)
Externí odkaz:
https://doaj.org/article/0adf9a28da2a414f934ad9aea8ba4d9e
Autor:
Alexandra N Marshall, Maria Camila Montealegre, Claudia Jiménez-López, Michael C Lorenz, Ambro van Hoof
Publikováno v:
PLoS Genetics, Vol 9, Iss 3, p e1003376 (2013)
Alternative splicing is commonly used by the Metazoa to generate more than one protein from a gene. However, such diversification of the proteome by alternative splicing is much rarer in fungi. We describe here an ancient fungal alternative splicing
Externí odkaz:
https://doaj.org/article/f9ccfac9378a4769a605c037be41ac2a
Autor:
Fabien Cottier, Martine Raymond, Oliver Kurzai, Marianne Bolstad, Worraanong Leewattanapasuk, Claudia Jiménez-López, Michael C Lorenz, Dominique Sanglard, Libuše Váchová, Norman Pavelka, Zdena Palková, Fritz A Mühlschlegel
Publikováno v:
PLoS Pathogens, Vol 8, Iss 1, p e1002485 (2012)
Like many organisms the fungal pathogen Candida albicans senses changes in the environmental CO(2) concentration. This response involves two major proteins: adenylyl cyclase and carbonic anhydrase (CA). Here, we demonstrate that CA expression is tigh
Externí odkaz:
https://doaj.org/article/d7f51e7a7f224854af485775cbef9da4
Autor:
Shantanu Guha, Shane A. Cristy, Giuseppe Buda De Cesare, Melissa R. Cruz, Michael C. Lorenz, Danielle A. Garsin
Publikováno v:
mBio, Vol 15, Iss 5 (2024)
ABSTRACTFungal resistance to commonly used medicines is a growing public health threat, and there is a dire need to develop new classes of antifungals. We previously described a peptide produced by Enterococcus faecalis, EntV, that restricts Candida
Externí odkaz:
https://doaj.org/article/8c1212e5524a427ca59b18cf3872ef30
Autor:
Michael C Lorenz
Publikováno v:
PLoS Biology, Vol 4, Iss 11, p e388 (2006)
Externí odkaz:
https://doaj.org/article/66f90c38e56b4e40ab99b360fccf32ef
Autor:
Callahan Katrak, Bruna A. Garcia, Louise M. Dornelas-Figueira, Mary Nguyen, Robert B. Williams, Michael C. Lorenz, Jacqueline Abranches
Publikováno v:
mSphere, Vol 8, Iss 5 (2023)
ABSTRACT Co-infection with Streptococcus mutans and Candida albicans is associated with dental caries, and their co-cultivation results in enhanced biofilm matrix production that contributes to increased virulence and caries risk. Moreover, the catal
Externí odkaz:
https://doaj.org/article/0add57403a0744ab8437657fc7e2c2fb