Zobrazeno 1 - 10
of 674
pro vyhledávání: '"Michael C Kolios"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Locally advanced breast cancer (LABC) is a severe type of cancer with a poor prognosis, despite advancements in therapy. As the disease is often inoperable, current guidelines suggest upfront aggressive neoadjuvant chemotherapy (NAC). Comple
Externí odkaz:
https://doaj.org/article/24dbe194c0ed426daeacd45f1dfd6efa
Autor:
Amir Moslemi, Laurentius Oscar Osapoetra, Archya Dasgupta, David Alberico, Maureen Trudeau, Sonal Gandhi, Andrea Eisen, Frances Wright, Nicole Look-Hong, Belinda Curpen, Michael C. Kolios, Gregory J. Czarnota
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
ObjectiveNeoadjuvant chemotherapy (NAC) is a key element of treatment for locally advanced breast cancer (LABC). Predicting the response to NAC for patients with Locally Advanced Breast Cancer (LABC) before treatment initiation could be beneficial to
Externí odkaz:
https://doaj.org/article/52a7c670cc744cb59889c1586cc43836
Autor:
Archya Dasgupta, Daniel DiCenzo, Lakshmanan Sannachi, Sonal Gandhi, Rossana C. Pezo, Andrea Eisen, Ellen Warner, Frances C. Wright, Nicole Look-Hong, Ali Sadeghi-Naini, Belinda Curpen, Michael C. Kolios, Maureen Trudeau, Gregory J. Czarnota
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundIn patients with locally advanced breast cancer (LABC) receiving neoadjuvant chemotherapy (NAC), quantitative ultrasound (QUS) radiomics can predict final responses early within 4 of 16-18 weeks of treatment. The current study was planned t
Externí odkaz:
https://doaj.org/article/e3c47ac0e2c74a71b7d223db1bbe8d39
Autor:
Tyler K. Hornsby, Farshad Moradi Kashkooli, Anshuman Jakhmola, Michael C. Kolios, Jahangir (Jahan) Tavakkoli
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Therapeutic ultrasound can be used to trigger the on-demand release of chemotherapeutic drugs from gold nanoparticles (GNPs). In the previous work, our group achieved doxorubicin (DOX) release from the surface of GNPS under low-intensity pul
Externí odkaz:
https://doaj.org/article/962dde9a9728489da872e0bf4df9646e
Autor:
Lakshmanan Sannachi, Laurentius O. Osapoetra, Daniel DiCenzo, Schontal Halstead, Frances Wright, Nicole Look-Hong, Elzbieta Slodkowska, Sonal Gandhi, Belinda Curpen, Michael C. Kolios, Michael Oelze, Gregory J. Czarnota
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract The purpose of this study was to investigate the performances of the tumor response prediction prior to neoadjuvant chemotherapy based on quantitative ultrasound, tumour core-margin, texture derivative analyses, and molecular parameters in a
Externí odkaz:
https://doaj.org/article/fd2d6e42d2a84578a404d6c600daac91
Autor:
Hossein Haghi, Michael C. Kolios
Publikováno v:
Ultrasonics Sonochemistry, Vol 104, Iss , Pp 106831- (2024)
Ultrasonically excited microbubbles (MBs) have numerous applications in various fields, such as drug delivery, and imaging. Ultrasonically excited MBs are known to be nonlinear oscillators that generate secondary acoustic emissions in the media when
Externí odkaz:
https://doaj.org/article/f949f33db0e54312879687831d583e6b
Publikováno v:
Drug Delivery, Vol 30, Iss 1 (2023)
AbstractFocused Ultrasound (FUS)-triggered nano-sized drug delivery, as a smart stimuli-responsive system for treating solid tumors, is computationally investigated to enhance localized delivery of drug and treatment efficacy. Integration of thermose
Externí odkaz:
https://doaj.org/article/9ea0f8a67cfb4919978d713d4dae7e31
Integrating Therapeutic Ultrasound With Nanosized Drug Delivery Systems in the Battle Against Cancer
Autor:
Farshad Moradi Kashkooli PhD, Anshuman Jakhmola PhD, Graham A. Ferrier PhD, Tyler K. Hornsby PhD, Jahangir (Jahan) Tavakkoli PhD, Michael C. Kolios PhD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 22 (2023)
Controlled, localized, and timely activation of nanosized drug delivery systems (NSDDSs), using an external stimulus such as therapeutic ultrasound (TUS), can improve the efficacy of cancer treatments compared to either conventional chemotherapy meth
Externí odkaz:
https://doaj.org/article/49c75e8e49bd4851b3f164f2ae5d494a
Autor:
Michaela B. Cooley, Eric C. Abenojar, Dana Wegierak, Anirban Sen Gupta, Michael C. Kolios, Agata A. Exner
Publikováno v:
Bioactive Materials, Vol 19, Iss , Pp 642-652 (2023)
Nanoscale ultrasound contrast agents, or nanobubbles, are being explored in preclinical applications ranging from vascular and cardiac imaging to targeted drug delivery in cancer. These sub-micron particles are approximately 10x smaller than clinical
Externí odkaz:
https://doaj.org/article/8836ca84b8b24bdf83baf8b4c8919b36
Autor:
Chuan Chen, Reshani Perera, Michael C. Kolios, Hessel Wijkstra, Agata A. Exner, Massimo Mischi, Simona Turco
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Investigation of nanobubble (NB) pharmacokinetics in contrast-enhanced ultrasound (CEUS) at the pixel level shows a unique phenomenon where the first pass of the contrast agent bolus is accompanied by a second wave. This effect has not been
Externí odkaz:
https://doaj.org/article/3af7678773fe48b4804334fb25e5af08