Výsledky vyhledávání

Akademický článek

Using the MCF10A/MCF10CA1a Breast Cancer Progression Cell Line Model to Investigate the Effect of Active, Mutant Forms of EGFR in Breast Cancer Development and Treatment Using Gefitinib.

Autor: Darrell C Bessette, Erik Tilch, Tatjana Seidens, Michael C J Quinn, Adrian P Wiegmans, Wei Shi, Sibylle Cocciardi, Amy McCart-Reed, Jodi M Saunus, Peter T Simpson, Sean M Grimmond, Sunil R Lakhani, Kum Kum Khanna, Nic Waddell, Fares Al-Ejeh, Georgia Chenevix-Trench

Publikováno v: PLoS ONE, Vol 10, Iss 5, p e0125232 (2015)

Basal-like and triple negative breast cancer (TNBC) share common molecular features, poor prognosis and a propensity for metastasis to the brain. Amplification of epidermal growth factor receptor (EGFR) occurs in ~50% of basal-like breast cancer, and

Externí odkaz: https://doaj.org/article/1aeb5efb8fdc47a187350d3ae92f42ba

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Kniha

Poetic interplay [elektronicky zdroj] : Catullus and Horace / Michael C.J. Putnam.

Autor: Putnam, Michael C. J.

Externí odkaz: Kolekce e-knih KNAV

Akademický článek

The genomic landscape of TP53 and p53 annotated high grade ovarian serous carcinomas from a defined founder population associated with patient outcome.

Autor: Paulina M Wojnarowicz, Kathleen Klein Oros, Michael C J Quinn, Suzanna L Arcand, Karen Gambaro, Jason Madore, Ashley H Birch, Manon de Ladurantaye, Kurosh Rahimi, Diane M Provencher, Anne-Marie Mes-Masson, Celia M T Greenwood, Patricia N Tonin

Publikováno v: PLoS ONE, Vol 7, Iss 9, p e45484 (2012)

High-grade ovarian serous carcinomas (HGSC) are characterized by TP53 mutations and non-random patterns of chromosomal anomalies, where the nature of the TP53 mutation may correlate with clinical outcome. However, the frequency of common somatic geno

Externí odkaz: https://doaj.org/article/9467faaf430c4f4db00a32587a331be2

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