Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Michael C Heck"'
Autor:
Susan A Holechek, Karen L Denzler, Michael C Heck, Jill Schriewer, R Mark Buller, Fatema A Legrand, Paulo H Verardi, Leslie A Jones, Tilahun Yilma, Bertram L Jacobs
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77879 (2013)
Post-exposure vaccination with vaccinia virus (VACV) has been suggested to be effective in minimizing death if administered within four days of smallpox exposure. While there is anecdotal evidence for efficacy of post-exposure vaccination this has no
Externí odkaz:
https://doaj.org/article/299781d8cc654d19aee1cd1f56066d3e
Autor:
Aleksandra Grozic, Zhela L. Sabir, Michael C. Heck, Ichiro Kaneko, Marya S. Sabir, Pamela A. Marshall, Sanchita Mallick, Carl E. Wagner, Christoper M. Dussik, Peter W. Jurutka
Publikováno v:
ACS Chemical Neuroscience. 12:857-871
There is considerable interest in identifying effective and safe drugs for neurodegenerative disorders. Cell culture and animal model work have demonstrated that modulating gene expression through RXR-mediated pathways may mitigate or reverse cogniti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d19d0b4aae7ea3236d25bdcc42e13d
https://doi.org/10.1021/acschemneuro.0c00707
https://doi.org/10.1021/acschemneuro.0c00707
Autor:
G. Kerr Whitfield, Zainab Khan, Elizabeth T. Jacobs, Sanchita Mallick, Marya S. Sabir, Christopher M. Dussik, Angelika Dampf Stone, Chengcheng Hu, Michael C. Heck, Michael A. Galligan, Shane F. Batie, Mark R. Haussler, Peter W. Jurutka
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 172:117-129
The hormonal metabolite of vitamin D, 1,25-dihydroxyvitamin D3 (1,25D), binds to the vitamin D receptor (VDR) and promotes heterodimerization of VDR with a retinoid-X-receptor (RXR) to genomically regulate diverse cellular processes. Herein, it is re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0f272924a4e181aff1b826e22bebfbb
https://doi.org/10.1016/j.jsbmb.2017.06.010
https://doi.org/10.1016/j.jsbmb.2017.06.010
Publikováno v:
Current Topics in Medicinal Chemistry. 17:742-767
Since the isolation and identification of the retinoid X receptor (RXR) as a member of the nuclear receptor (NR) superfamily in 1990, its analysis has ushered in a new understanding of physiological regulation by nuclear receptors, and novel methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::babd4b0aef89de8dbf2f15992286affc
https://doi.org/10.2174/1568026616666160617091559
https://doi.org/10.2174/1568026616666160617091559
Autor:
Arjan van der Vaart, Michael C. Heck, Carl E. Wagner, Pritika H. Shahani, Aleksandra Grozic, Nathan M. Robinson, Tamana Darwaiz, Mairi MacNeill, Micah Shimabuku, Ning Ma, Peter W. Jurutka, Joseph W. Ziller, David G. Deans, Samer H. Salama, Pamela A. Marshall
Publikováno v:
Journal of Medicinal Chemistry. 59:8924-8940
Sulfonic acid analogues of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene, 1) as well as seven novel and two reported analogues of 6-(ethyl(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)amino)nicoti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ab0d3dba43dcb4696c24f88f6d71eac
https://doi.org/10.1021/acs.jmedchem.6b00812
https://doi.org/10.1021/acs.jmedchem.6b00812
Autor:
Michael C. Heck, Pritika H. Shahani, Carl E. Wagner, Peter W. Jurutka, Lech J. P. Staniszewski, Dania S. Hasan
Publikováno v:
The FASEB Journal. 32
Antagonists are chemical compounds that bind to receptors without eliciting activation of signaling, therefore the biochemical response to the receptor ligand can be blocked or significantly decrea...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db8cf45a07674650d79b42485f266803
https://doi.org/10.1096/fasebj.2018.32.1_supplement.lb98
https://doi.org/10.1096/fasebj.2018.32.1_supplement.lb98
Autor:
Latha Tripuraneni, James K. Jancovich, Jeffrey Langland, Michael C. Heck, Bertram L. Jacobs, Trung Huynh
Ambystoma tigrinum virus (ATV) (family Iridoviridae, genus Ranavirus) was isolated from diseased tiger salamanders (Ambystoma tigrinum stebbinsi) from the San Rafael Valley in southern Arizona, USA in 1996. Genomic sequencing of ATV, as well as other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e7765bbe3556d76d657a17a2228132
https://europepmc.org/articles/PMC6192022/
https://europepmc.org/articles/PMC6192022/
Autor:
Marya S, Sabir, Zainab, Khan, Chengcheng, Hu, Michael A, Galligan, Christopher M, Dussik, Sanchita, Mallick, Angelika Dampf, Stone, Shane F, Batie, Elizabeth T, Jacobs, G Kerr, Whitfield, Mark R, Haussler, Michael C, Heck, Peter W, Jurutka
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 172
The hormonal metabolite of vitamin D, 1,25-dihydroxyvitamin D3 (1,25D), binds to the vitamin D receptor (VDR) and promotes heterodimerization of VDR with a retinoid-X-receptor (RXR) to genomically regulate diverse cellular processes. Herein, it is re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1fd872e9935e30745b84f29743da349
https://pubmed.ncbi.nlm.nih.gov/28636886
https://pubmed.ncbi.nlm.nih.gov/28636886
Autor:
Sangeetha Vijaysri, Garilyn Jentarra, Michael C. Heck, Andrew A. Mercer, Colin J. McInnes, Bertram L. Jacobs
Publikováno v:
Vaccine. 26:664-676
Vaccinia virus (VACV) has been used as the vaccine to protect against smallpox, and recombinant VACVs have been used to develop vaccine candidates against numerous cancers and infectious diseases. Although relatively safe for use in humans, the strai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7985d8422cb9c2f7edd56df1f65ad4f0
https://doi.org/10.1016/j.vaccine.2007.11.045
https://doi.org/10.1016/j.vaccine.2007.11.045
Publikováno v:
Journal of Bacteriology. 187:6770-6778
The rcs phosphorelay pathway components were originally identified as regulators of capsule synthesis. In addition to the transmembrane sensor kinase RcsC, the RcsA coregulator, and the response regulator RcsB, two new components have been characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f3e924a636d8b9e5c4d68ea06f5b036
https://doi.org/10.1128/jb.187.19.6770-6778.2005
https://doi.org/10.1128/jb.187.19.6770-6778.2005