Výsledky vyhledávání - "Michael C Hart"

NIR Fluorescent Imaging and Photodynamic Therapy with a Novel Theranostic Phospholipid Probe for Triple-Negative Breast Cancer Cells

Autor: Theresa M. Busch, Alejandro D. Arroyo, Benjamin K. Liebov, Natalia I. Rubtsova, Michael C Hart, Nadia Anikeeva, Anatoliy V. Popov, Sanghoon Chong, Joann Miller, E. James Delikatny, Sofya A Osharovich, Jeffrey M. Cochran, Min Yuan, Arjun G. Yodh

Publikováno v: Bioconjugate Chemistry. 32:1852-1863

New exogenous probes are needed for both imaging diagnostics and therapeutics. Here, we introduce a novel nanocomposite near-infrared (NIR) fluorescent imaging probe and test its potency as a photosensitizing agent for photodynamic therapy (PDT) agai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c68ef3a5f8f19e9bdbd8a21fc0a65024
https://doi.org/10.1021/acs.bioconjchem.1c00295

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Selective Substitution of One of the Substituents on Germanium in Coordinatively Unsaturated Ruthenium Germyl Complexes

Autor: Peter D. W. Boyd, L. James Wright, Michael C. Hart, Warren R. Roper, Julian R. F. Pritzwald-Stegmann

Publikováno v: Organometallics. 31:2914-2921

The coordinatively unsaturated tri-p-tolylgermyl complex RuCl(Ge[p-tolyl]3)(CO)(PPh3)2 (1) is obtained in good yield through the reaction between HGe(p-tolyl)3 and RuCl(Ph)(CO)(PPh3)2. On treatment of 1 with 1 equiv of NaS2CNR′2 (R′ = Et, Me), th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2108dfbb8145194a9e257bf6d9f22af5
https://doi.org/10.1021/om201239a

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Attenuation of Signaling and Nitric Oxide Production following Prolonged Leptin Exposure in Human Aortic Endothelial Cells

Autor: Carmelo Blanquicett, Michael C. Hart, Dean J. Kleinhenz, A. S. Graves

Publikováno v: Journal of Investigative Medicine. 55:368-377

Acute leptin exposure stimulates endothelial nitric oxide (NO) production in vitro. In contrast, chronic elevations in circulating leptin levels in patients with obesity are associated with endothelial dysfunction and impaired endothelial NO producti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ed28e8d2e6bb70a11cc07e16d246c1
https://doi.org/10.2310/6650.2007.00017

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Alcohol Abuse and Acute Lung Injury: Epidemiology and Pathophysiology of a Recently Recognized Association

Autor: David M. Guidot, Michael C. Hart

Publikováno v: Journal of Investigative Medicine. 53:235-245

Alcohol is the most commonly used and abused drug in the United States. The deleterious health effects of alcohol can be attributed both to its acute intoxicating effects, which result in temporary impairment of judgment and motor skills, and to its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a3c93696199486de9891468c4d7bfa7
https://doi.org/10.2310/6650.2005.53506

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Fatty Acids Differentially Modulate Insulin-Stimulated Endothelial Nitric Oxide Production by an Akt-Independent Pathway

Autor: William A. Kanner, Samuel C. Dudley, Dean J. Kleinhenz, Michael C. Hart, Matthew A. Lynn, Heidi L. Rupnow

Publikováno v: Experts@Minnesota

Background Insulin increases endothelial nitric oxide (NO) production by activating endothelial nitric oxide synthase (eNOS) through protein kinase B (Akt)-mediated phosphorylation of serine residue 1179 (p-eNOS serine 1179). Because fatty acids modu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca6acbb847eca6e3d3460c8fbe7b157
https://doi.org/10.1097/00042871-200403000-00022

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