Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Michael C, Hacker"'
Autor:
Hanluo Li, Martin Wilhelm, Christina Marie Baumbach, Michael C. Hacker, Michael Szardenings, Klaus Rischka, Andreas Koenig, Ellen Schulz-Kornas, Florian Fuchs, Jan Christoph Simon, Bernd Lethaus, Vuk Savković
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5927 (2024)
This study presents the effects of treating polystyrene (PS) cell culture plastic with oxidoreductase enzyme laccase and the catechol substrates caffeic acid (CA), L-DOPA, and dopamine on the culturing of normal human epidermal melanocytes (NHEMs) an
Externí odkaz:
https://doaj.org/article/47daaa2def0549c1948e14c63ae03db2
Autor:
Barbara Wenzel, Maximilian Schmid, Rodrigo Teodoro, Rareş-Petru Moldovan, Thu Hang Lai, Franziska Mitrach, Klaus Kopka, Björn Fischer, Michaela Schulz-Siegmund, Peter Brust, Michael C. Hacker
Publikováno v:
Nanomaterials, Vol 13, Iss 14, p 2095 (2023)
This study describes the synthesis, radiofluorination and purification of an anionic amphiphilic teroligomer developed as a stabilizer for siRNA-loaded calcium phosphate nanoparticles (CaP-NPs). As the stabilizing amphiphile accumulates on nanopartic
Externí odkaz:
https://doaj.org/article/28fabb821ae147ffb6d8c01327a161ab
Autor:
Sandra Hinkelmann, Alexandra H. Springwald, Annett Starke, Hermann Kalwa, Christian Wölk, Michael C. Hacker, Michaela Schulz-Siegmund
Publikováno v:
Materials Today Bio, Vol 13, Iss , Pp 100190- (2022)
The aim of this study was the evaluation of cross-linked gelatin microparticles (cGM) as substrates for osteogenic cell culture to assemble 3D microtissues and their use as delivery system for siRNA to cells in these assemblies.In a 2D transwell cult
Externí odkaz:
https://doaj.org/article/aa7736821e854c35959eb81215a15189
Autor:
Jan Krieghoff, Ann-Kristin Picke, Juliane Salbach-Hirsch, Sandra Rother, Christiane Heinemann, Ricardo Bernhardt, Christian Kascholke, Stephanie Möller, Martina Rauner, Matthias Schnabelrauch, Vera Hintze, Dieter Scharnweber, Michaela Schulz-Siegmund, Michael C. Hacker, Lorenz C. Hofbauer, Christine Hofbauer
Publikováno v:
Biomaterials Research, Vol 23, Iss 1, Pp 1-13 (2019)
Abstract Background Delayed bone regeneration of fractures in osteoporosis patients or of critical-size bone defects after tumor resection are a major medical and socio-economic challenge. Therefore, the development of more effective and osteoinducti
Externí odkaz:
https://doaj.org/article/77ef2e29565f47bda429da3a9e156256
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 572 (2022)
A three-dimensional (3D) scaffold ideally provides hierarchical complexity and imitates the chemistry and mechanical properties of the natural cell environment. Here, we report on a stimuli-responsive photo-cross-linkable resin formulation for the fa
Externí odkaz:
https://doaj.org/article/9f3a344a9b0746cf8d5599512e19fb17
Autor:
Sandra Hinkelmann, Alexandra H. Springwald, Sabine Schulze, Ute Hempel, Franziska Mitrach, Christian Wölk, Michael C. Hacker, Michaela Schulz-Siegmund
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 548 (2022)
The local release of complexed siRNA from biomaterials opens precisely targeted therapeutic options. In this study, complexed siRNA was loaded to gelatin microparticles cross-linked (cGM) with an anhydride-containing oligomer (oPNMA). We aggregated t
Externí odkaz:
https://doaj.org/article/16acdbcb26d5475296e6d2e562b71526
Autor:
Franziska Mitrach, Maximilian Schmid, Magali Toussaint, Sladjana Dukic-Stefanovic, Winnie Deuther-Conrad, Heike Franke, Alexander Ewe, Achim Aigner, Christian Wölk, Peter Brust, Michael C. Hacker, Michaela Schulz-Siegmund
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 326 (2022)
Convection-enhanced delivery (CED) has been introduced as a concept in cancer treatment to generate high local concentrations of anticancer therapeutics and overcome the limited diffusional distribution, e.g., in the brain. RNA interference provides
Externí odkaz:
https://doaj.org/article/a2442b8c8e9d46428d86ea4ed200a1d3
Autor:
Lysann M. Kroschwald, Felix Allerdt, Anne Bernhardt, Sandra Rother, Kai Zheng, Iram Maqsood, Norbert Halfter, Christiane Heinemann, Stephanie Möller, Matthias Schnabelrauch, Michael C. Hacker, Stefan Rammelt, Aldo R. Boccaccini, Vera Hintze
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 12819 (2021)
The present study analyzes the capacity of collagen (coll)/sulfated glycosaminoglycan (sGAG)-based surface coatings containing bioactive glass nanoparticles (BGN) in promoting the osteogenic differentiation of human mesenchymal stroma cells (hMSC). P
Externí odkaz:
https://doaj.org/article/9b385991e1294880a2e51dc609e79bfc
Autor:
Jan Krieghoff, Johannes Rost, Caroline Kohn-Polster, Benno M. Müller, Andreas Koenig, Tobias Flath, Michaela Schulz-Siegmund, Fritz-Peter Schulze, Michael C. Hacker
Publikováno v:
Biomedicines, Vol 9, Iss 4, p 370 (2021)
The performance of artificial nerve guidance conduits (NGC) in peripheral nerve regeneration can be improved by providing structures with multiple small channels instead of a single wide lumen. 3D-printing is a strategy to access such multi-channeled
Externí odkaz:
https://doaj.org/article/4d482e724ae741c8a7ec9fea2c4d0ebd
Autor:
Dzmitry Kuzmenka, Claudia Sewohl, Andreas König, Tobias Flath, Sebastian Hahnel, Fritz Peter Schulze, Michael C. Hacker, Michaela Schulz-Siegmund
Publikováno v:
Pharmaceutics, Vol 12, Iss 12, p 1192 (2020)
In this study, we integrated different calcium sources into sol-gel hybrid glass scaffolds with the aim of producing implants with long-lasting calcium release while maintaining mechanical strength of the implant. Calcium(II)-release was used to intr
Externí odkaz:
https://doaj.org/article/1953a005c7e349e2b834893be7d3568a