Zobrazeno 1 - 10
of 202 633
pro vyhledávání: '"Michael C"'
Autor:
Lubayna S. Elahi, Michael C. Condro, Riki Kawaguchi, Yue Qin, Alvaro G. Alvarado, Brandon Gruender, Haocheng Qi, Tie Li, Albert Lai, Maria G. Castro, Pedro R. Lowenstein, Matthew C. Garrett, Harley I. Kornblum
Publikováno v:
npj Metabolic Health and Disease, Vol 2, Iss 1, Pp 1-14 (2024)
Abstract Histone deacetylases (HDACs) have a wide range of targets and can rewire both the chromatin and lipidome of cancer cells. In this study, we show that valproic acid (VPA), a brain penetrant anti-seizure medication and histone deacetylase inhi
Externí odkaz:
https://doaj.org/article/ecf370d8942a4622b169a6b1429e57e4
Autor:
Michael C. Robertson, Maria Chang Swartz, Karen M. Basen-Engquist, Yisheng Li, Kristofer Jennings, Debbe Thompson, Tom Baranowski, Elena Volpi, Elizabeth J. Lyons
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Older adult women often do not engage in sufficient physical activity (PA) and can encounter biological changes that exacerbate the negative effects of inadequate activity. Wearable activity monitors can facilitate PA initiation,
Externí odkaz:
https://doaj.org/article/e69da11084694703b2b5e0cb7e461d03
Autor:
Fahad Paryani, Ji-Sun Kwon, Christopher W. Ng, Kelly Jakubiak, Nacoya Madden, Kenneth Ofori, Alice Tang, Hong Lu, Shengnan Xia, Juncheng Li, Aayushi Mahajan, Shawn M. Davidson, Anna O. Basile, Caitlin McHugh, Jean Paul Vonsattel, Richard Hickman, Michael C. Zody, David E. Housman, James E. Goldman, Andrew S. Yoo, Vilas Menon, Osama Al-Dalahmah
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract The mechanisms underlying the selective regional vulnerability to neurodegeneration in Huntington’s disease (HD) have not been fully defined. To explore the role of astrocytes in this phenomenon, we used single-nucleus and bulk RNAseq, lip
Externí odkaz:
https://doaj.org/article/8951e53b83a446a78dbb4875a502960b
Autor:
Marvin Collins, Matthew B. Lau, William Ma, Aidan Shen, Brenda Wang, Sa Cai, Marie La Russa, Michael C. Jewett, Lei S. Qi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Equitable and accessible education in life sciences, bioengineering, and synthetic biology is crucial for training the next generation of scientists, fostering transparency in public decision-making, and ensuring biotechnology can benefit a
Externí odkaz:
https://doaj.org/article/13bf1b7f40324d2cbf38a22a2f965e59
Autor:
Olivier Barnouin, Ronald-Louis Ballouz, Simone Marchi, Jean-Baptiste Vincent, Harrison Agrusa, Yun Zhang, Carolyn M. Ernst, Maurizio Pajola, Filippo Tusberti, Alice Lucchetti, R. Terik Daly, Eric Palmer, Kevin J. Walsh, Patrick Michel, Jessica M. Sunshine, Juan L. Rizos, Tony L. Farnham, Derek C. Richardson, Laura M. Parro, Naomi Murdoch, Colas Q. Robin, Masatoshi Hirabayashi, Tomas Kahout, Erik Asphaug, Sabina D. Raducan, Martin Jutzi, Fabio Ferrari, Pedro Henrique Aragao Hasselmann, Adriano CampoBagatin, Nancy L. Chabot, Jian-Yang Li, Andrew F. Cheng, Michael C. Nolan, Angela M. Stickle, Ozgur Karatekin, Elisabetta Dotto, Vincenzo Della Corte, Elena Mazzotta Epifani, Alessandro Rossi, Igor Gai, Jasinghege Don Prasanna Deshapriya, Ivano Bertini, Angelo Zinzi, Josep M. Trigo-Rodriguez, Joel Beccarelli, Stavro Lambrov Ivanovski, John Robert Brucato, Giovanni Poggiali, Giovanni Zanotti, Marilena Amoroso, Andrea Capannolo, Gabriele Cremonese, Massimo Dall’Ora, Simone Ieva, Gabriele Impresario, Michèle Lavagn, Dario Modenini, Pasquale Palumbo, Davide Perna, Simone Pirrotta, Paolo Tortora, Marco Zannoni, Andrew S. Rivkin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Images collected during NASA’s Double Asteroid Redirection Test (DART) mission provide the first resolved views of the Didymos binary asteroid system. These images reveal that the primary asteroid, Didymos, is flattened and has plausible u
Externí odkaz:
https://doaj.org/article/0d20cb5093344cc2bbc9fb35eeab0876
Autor:
Andrea Cortese, Sarah J. Beecroft, Stefano Facchini, Riccardo Curro, Macarena Cabrera-Serrano, Igor Stevanovski, Sanjog R. Chintalaphani, Hasindu Gamaarachchi, Ben Weisburd, Chiara Folland, Gavin Monahan, Carolin K. Scriba, Lein Dofash, Mridul Johari, Bianca R. Grosz, Melina Ellis, Liam G. Fearnley, Rick Tankard, Justin Read, Ashirwad Merve, Natalia Dominik, Elisa Vegezzi, Ricardo P. Schnekenberg, Gorka Fernandez-Eulate, Marion Masingue, Diane Giovannini, Martin B. Delatycki, Elsdon Storey, Mac Gardner, David J. Amor, Garth Nicholson, Steve Vucic, Robert D. Henderson, Thomas Robertson, Jason Dyke, Vicki Fabian, Frank Mastaglia, Mark R. Davis, Marina Kennerson, OPDM study group, Ros Quinlivan, Simon Hammans, Arianna Tucci, Melanie Bahlo, Catriona A. McLean, Nigel G. Laing, Tanya Stojkovic, Henry Houlden, Michael G. Hanna, Ira W. Deveson, Paul J. Lockhart, Phillipa J. Lamont, Michael C. Fahey, Enrico Bugiardini, Gianina Ravenscroft
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Oculopharyngodistal myopathy (OPDM) is an inherited myopathy manifesting with ptosis, dysphagia and distal weakness. Pathologically it is characterised by rimmed vacuoles and intranuclear inclusions on muscle biopsy. In recent years CGG •
Externí odkaz:
https://doaj.org/article/efb3c57b4f0d4386a06f31ca1da16fc6
Autor:
Kelsey E. Johnson, Nelmary Hernandez-Alvarado, Mark Blackstad, Timothy Heisel, Mattea Allert, David A. Fields, Elvira Isganaitis, Katherine M. Jacobs, Dan Knights, Eric F. Lock, Michael C. Rudolph, Cheryl A. Gale, Mark R. Schleiss, Frank W. Albert, Ellen W. Demerath, Ran Blekhman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Human cytomegalovirus (CMV) is a highly prevalent herpesvirus that is often transmitted to the neonate via breast milk. Postnatal CMV transmission can have negative health consequences for preterm and immunocompromised infants, but any effec
Externí odkaz:
https://doaj.org/article/512139a4b7ec4a86b3bee9afd7abcc3a
Autor:
Meijie Tian, Jun S. Wei, Adam Tai-Chi Cheuk, David Milewski, Zhongmei Zhang, Yong Yean Kim, Hsien-Chao Chou, Can Liu, Sherif Badr, Eleanor G. Pope, Abdelrahman Rahmy, Jerry T. Wu, Michael C. Kelly, Xinyu Wen, Javed Khan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Chimeric antigen receptor (CAR) T-cells targeting Fibroblast Growth Factor Receptor 4 (FGFR4), a highly expressed surface tyrosine receptor in rhabdomyosarcoma (RMS), are already in the clinical phase of development, but tumour heterogeneity
Externí odkaz:
https://doaj.org/article/a3964d3bf8e04e298aea51cf07822727
Autor:
Alvaro Quintanal-Villalonga, Kenta Kawasaki, Esther Redin, Fathema Uddin, Swanand Rakhade, Vidushi Durani, Amin Sabet, Moniquetta Shafer, Wouter R. Karthaus, Samir Zaidi, Yingqian A. Zhan, Parvathy Manoj, Harsha Sridhar, Dennis Kinyua, Hong Zhong, Barbara P. Mello, Metamia Ciampricotti, Umesh K. Bhanot, Irina Linkov, Juan Qiu, Radhika A. Patel, Colm Morrissey, Sanjoy Mehta, Jesse Barnes, Michael C. Haffner, Nicholas D. Socci, Richard P. Koche, Elisa de Stanchina, Sonia Molina-Pinelo, Sohrab Salehi, Helena A. Yu, Joseph M. Chan, Charles M. Rudin
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract Neuroendocrine (NE) transformation is a mechanism of resistance to targeted therapy in lung and prostate adenocarcinomas leading to poor prognosis. Up to date, even if patients at high risk of transformation can be identified by the occurren
Externí odkaz:
https://doaj.org/article/501fe4c8a5e9423ca573e0d9f455d0b2
Autor:
Andrews Korah, Michael C. Wimberly
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-15 (2024)
Abstract Impervious surface data are increasingly important for research and planning. Despite the availability of global and local urban land cover maps, regional data are lacking in Africa. We generated annual 30 m impervious cover data from 2001
Externí odkaz:
https://doaj.org/article/a42cc8923107446595f9c5d06d807c76