Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Michael Bscheider"'
Autor:
Alberto Valdeolivas, Bettina Amberg, Nicolas Giroud, Marion Richardson, Eric J. C. Gálvez, Solveig Badillo, Alice Julien-Laferrière, Demeter Túrós, Lena Voith von Voithenberg, Isabelle Wells, Benedek Pesti, Amy A. Lo, Emilio Yángüez, Meghna Das Thakur, Michael Bscheider, Marc Sultan, Nadine Kumpesa, Björn Jacobsen, Tobias Bergauer, Julio Saez-Rodriguez, Sven Rottenberg, Petra C. Schwalie, Kerstin Hahn
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-16 (2024)
Abstract The consensus molecular subtypes (CMS) of colorectal cancer (CRC) is the most widely-used gene expression-based classification and has contributed to a better understanding of disease heterogeneity and prognosis. Nevertheless, CMS intratumor
Externí odkaz:
https://doaj.org/article/d6bdaa8d602c4df587d26a3ae4c61323
Autor:
S Jordan Kerns, Chaitra Belgur, Debora Petropolis, Marianne Kanellias, Riccardo Barrile, Johannes Sam, Tina Weinzierl, Tanja Fauti, Anne Freimoser-Grundschober, Jan Eckmann, Carina Hage, Martina Geiger, Patrick Ray Ng, William Tien-Street, Dimitris V Manatakis, Virginie Micallef, Regine Gerard, Michael Bscheider, Ekaterina Breous-Nystrom, Anneliese Schneider, Anna Maria Giusti, Cristina Bertinetti-Lapatki, Heather Shannon Grant, Adrian B Roth, Geraldine A Hamilton, Thomas Singer, Katia Karalis, Annie Moisan, Peter Bruenker, Christian Klein, Marina Bacac, Nikolce Gjorevski, Lauriane Cabon
Publikováno v:
eLife, Vol 10 (2021)
Traditional drug safety assessment often fails to predict complications in humans, especially when the drug targets the immune system. Here, we show the unprecedented capability of two human Organs-on-Chips to evaluate the safety profile of T-cell bi
Externí odkaz:
https://doaj.org/article/65e3b07242e4472a8bccea9ce9f5ca1b
Autor:
Simon Heidegger, Diana Kreppel, Michael Bscheider, Florian Stritzke, Tatiana Nedelko, Alexander Wintges, Sarah Bek, Julius C. Fischer, Theresa Graalmann, Ulrich Kalinke, Florian Bassermann, Tobias Haas, Hendrik Poeck
Publikováno v:
EBioMedicine, Vol 41, Iss , Pp 146-155 (2019)
Background: Antibody-mediated targeting of regulatory T cell receptors such as CTLA-4 enhances antitumor immune responses against several cancer entities including malignant melanoma. Yet, therapeutic success in patients remains variable underscoring
Externí odkaz:
https://doaj.org/article/d674e7d8808542dc831fe18aab53dc03
Autor:
Denis Dermadi, Michael Bscheider, Kristina Bjegovic, Nicole H. Lazarus, Agata Szade, Husein Hadeiba, Eugene C. Butcher
Publikováno v:
iScience, Vol 23, Iss 2, Pp - (2020)
Summary: High-dimensional single cell profiling coupled with computational modeling is emerging as a powerful tool to elucidate developmental programs directing cell lineages. We introduce tSpace, an algorithm based on the concept of “trajectory sp
Externí odkaz:
https://doaj.org/article/0449d657d72b45c6875a37de6f11f54a
Autor:
Borja Ocón, Junliang Pan, Theresa Thu Dinh, Wenjing Chen, Romain Ballet, Michael Bscheider, Aida Habtezion, Hua Tu, Brian A. Zabel, Eugene C. Butcher
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Chemoattractants control lymphocyte recruitment from the blood, contributing to the systemic organization of the immune system. The G protein-linked receptor GPR15 mediates lymphocyte homing to the large intestines and skin. Here we show that the 9 k
Externí odkaz:
https://doaj.org/article/dbeb0205d39f41918c7a2f0ae191301c
Autor:
Alberto Valdeolivas, Bettina Amberg, Nicolas Giroud, Marion Richardson, Eric J.C. Gálvez, Solveig Badillo, Alice Julien-Laferrière, Demeter Turos, Lena Voith von Voithenberg, Isabelle Wells, Amy A. Lo, Emilio Yángüez, Meghna Das Thakur, Michael Bscheider, Marc Sultan, Nadine Kumpesa, Björn Jacobsen, Tobias Bergauer, Julio Saez-Rodriguez, Sven Rottenberg, Petra C. Schwalie, Kerstin Hahn
The heterogeneity of colorectal cancer (CRC) contributes to substantial differences in patient response to standard therapies. The consensus molecular subtypes (CMS) of CRC is the most widely-used gene expression-based classification and has contribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da944b295388b36f4162857fc1d22e05
https://doi.org/10.1101/2023.01.23.525135
https://doi.org/10.1101/2023.01.23.525135
Autor:
Anne Freimoser-Grundschober, Ekaterina Breous-Nystrom, Heather Shannon Grant, Chaitra Belgur, Carina Hage, Anna Maria Giusti, Régine Gérard, Patrick Ray Ng, Martina Geiger, Lauriane Cabon, Adrian Roth, Katia Karalis, Nikolce Gjorevski, Tanja Fauti, Dimitris V. Manatakis, Johannes Sam, Christian Klein, William Tien-Street, Tina Weinzierl, Virginie Micallef, Thomas Singer, Anneliese Schneider, Debora B. Petropolis, Annie Moisan, Peter Bruenker, Jan Eckmann, Geraldine A. Hamilton, S. Jordan Kerns, Cristina Bertinetti-Lapatki, Riccardo Barrile, Michael Bscheider, Marina Bacac, Marianne Kanellias
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3636b0fb4a5bf02fa3e3ab9b2eb29a8
https://doi.org/10.7554/elife.67106.sa2
https://doi.org/10.7554/elife.67106.sa2
Autor:
Katia Karalis, Anneliese Schneider, Riccardo Barrile, Annie Moisan, Peter Bruenker, William Tien-Street, Michael Bscheider, Patrick Ray Ng, Régine Gérard, Tanja Fauti, Anna Maria Giusti, Debora B. Petropolis, Ekaterina Breous-Nystrom, Marina Bacac, Johannes Sam, Thomas Singer, Adrian Roth, Nikolce Gjorevski, Tina Weinzierl, Virginie Micallef, Lauriane Cabon, Dimitris V. Manatakis, Carina Hage, Cristina Bertinetti-Lapatki, Jan Eckmann, Geraldine A. Hamilton, Christian Klein, S. Jordan Kerns, Chaitra Belgur, Marianne Kanellias, Anne Freimoser-Grundschober, Heather Shannon Grant, Martina Geiger
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Traditional drug safety assessment often fails to predict complications in humans, especially when the drug targets the immune system. Here, we show the unprecedented capability of two Organs-on-Chips to evaluate the safety profile of T-cell bispecif
Autor:
Annie Moisan, Adrian Roth, Nikolce Gjorevski, Blandine Avignon, Lauriane Cabon, Régine Gérard, Michael Bscheider
Publikováno v:
Lab on a chip. 20(18)
The multiphasic etiology of tissue inflammation and the fundamental immunological differences between species render inflammatory pathologies difficult to recapitulate in animal models, and account for the paucity of therapies that are successfully t
Autor:
Michael Bscheider, Agata Szade, Denis Dermadi, Kristina Bjegovic, Husein Hadeiba, Nicole H. Lazarus, Eugene C. Butcher
Publikováno v:
iScience, Vol 23, Iss 2, Pp-(2020)
iScience, vol 23, iss 2
iScience
iScience, vol 23, iss 2
iScience
Summary High-dimensional single cell profiling coupled with computational modeling is emerging as a powerful tool to elucidate developmental programs directing cell lineages. We introduce tSpace, an algorithm based on the concept of “trajectory spa