Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Michael Bruening"'
Autor:
Stefan Gradl, Sooncheol Lee, Martin Lange, Xiaoyun Wu, Silvia Goldoni, Timothy Lewis, Charlotte Kopitz, Colin Garvie, Philip Lienau, Stephanie Hoyt, Henrik Seidel, Stephan Kaulfuss, Manuel Ellermann, Luc de Waal, Adrian Tersteegen, Sven Golfier, Detlev Suelzle, Christa Hegele-Hartung, James Carr, Frederick Brookfield, Michael Bruening, Melanie Berthold, Thibaud Jourdan, Monica Schenone, Galen Gao, Joseph McGaunn, Antje Wengner, Elisa Aquilanti, Franziska Siegel, Marine Garrido, Annette Walter, Isabelle Genvresse, Andrew Cherniack, Stuart Schreiber, Knut Eis, Ashley Eheim, Matthew Meyerson, Heidi Greulich
Publikováno v:
Cancer Research. 82:ND04-ND04
Velcrin compounds are a class of small molecules that induce complex formation between PDE3A and SLFN12, killing cancer cells that express elevated levels of these two proteins by a mechanism independent of PDE3A enzymatic inhibition. Instead, PDE3A
Autor:
Michael Bruening
Publikováno v:
Theodore Beza at 500
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f018d340a0c94acc5cf95172ad93e6ad
https://doi.org/10.13109/9783666560415.57
https://doi.org/10.13109/9783666560415.57
Autor:
Claudia Merz, Marcus Bauser, Martin Michels, Ashley Eheim, David T. Scadden, Henrik Seidel, Ralf Lesche, Timo Stellfeld, Hanna Meyer, Pascale Lejeune, Thomas Mueller, Detlef Stoeckigt, David B. Sykes, Steven James Ferrara, Sven Christian, Andrea Haegebarth, Judith Guenther, Andreas Janzer, Katja Zimmermann, Sherif El Sheikh, Stefan Gradl, Michael Bruening
Publikováno v:
Cancer Research. 78:DDT02-04
Acute myeloid leukemia (AML), the most common acute leukemia in adults, is an aggressive hematologic malignancy resulting in bone marrow failure with a poor outcome; overall survival is approximately 25% at five years. Treatment options, in particula
Autor:
Katja Zimmermann, Henrik Seidel, Vera Puetter, Sherif El Sheikh, Steven James Ferrara, Stefan Gradl, Claudia Merz, Anders Friberg, Sven Christian, Andrea Haegebarth, Thomas Mueller, Ashley Eheim, Timo Stellfeld, David T. Scadden, Marcus Bauser, Duy Nguyen, Michael Niehues, Martina Schaefer, Michael Bruening, Martin Michels, Judith Guenther, Knut Eis, Detlef Stoeckigt, Hanna Meyer, Pascal Lejeune, Andreas Janzer, Han-Jie Zhou, David B. Sykes, Michael Kroeber
Publikováno v:
Cancer Research. 79:2-2
DHODH is a key enzyme in the biosynthesis of pyrimidines and recent studies have renewed interest in this old anti-cancer target. Here, we disclose the discovery of 4-triazolosalicylamides as inhibitors of DHODH and their structure activity relations
Autor:
Michael Bruening
Publikováno v:
Reformation & Renaissance Review. 10:125-136
Autor:
Michael Bruening
Publikováno v:
The Catholic Historical Review. 98:375-377
Publikováno v:
Erlang Workshop
Ericsson's OTP (Open Telecom Platform) offers a number of attractive features if you want to provide a variety of information services on a network with high availability, scalability, and extensibility. However, the major uses of OTP have been in cl