Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Michael Boubelik"'
Autor:
Vladimir Bobek, Katarina Kolostova, Daniela Pinterova, Oliver Taltynov, Marie Jirkovská, Otakar Raška, Michael Boubelik, Pavel Hozák
Publikováno v:
American Journal of Otolaryngology. 33:68-74
Aims The identification of growth factors and cytokines with angiogenic activity has enabled new therapeutic treatments for a variety of diseases; this concept is called therapeutic angiogenesis. The vascular endothelial growth factor (VEGF) is the m
Autor:
Pavel Lebduška, Marie Malissen, Petr Dráber, Petr Heneberg, Petra Volná, Lubica Dráberová, Viktor Bugajev, Bridget S. Wilson, Michael Boubelik, Šárka Šímová, Bernard Malissen, Vaclav Horejsi
Publikováno v:
The Journal of Experimental Medicine
Engagement of the Fcepsilon receptor I (FcepsilonRI) on mast cells and basophils initiates signaling pathways leading to degranulation. Early activation events include tyrosine phosphorylation of two transmembrane adaptor proteins, linker for activat
Autor:
Meng Yang, Michael Boubelik, Daniela Pinterova, Jiri Plachy, Vladimir Bobek, Robert M. Hoffman, Katarina Kolostova, Ping Jiang
Publikováno v:
Clinical & Experimental Metastasis. 21:347-352
The chick-embryo model has been an important tool to study tumor growth, metastasis, and angiogenesis. However, an imageable model with a genetic fluorescent tag in the growing and spreading cancer cells that is stable over time has not been develope
Publikováno v:
The Journal of Immunology. 171:3585-3593
Gangliosides released from tumor cells, as well as administered exogenously, suppress the immune responses by largely unknown mechanisms. We show here that a pretreatment of rat basophilic leukemia cells with isolated brain gangliosides inhibited the
Publikováno v:
American Journal of Reproductive Immunology. 47:311-318
PROBLEM: To determine the influence of an endocrine disruptor [bisphenol-A (BPA)] on the integrated reproductive process as well as on individual reproductive organs and gametes in order to select suitable markers for testing sperm damage. METHOD OF
Autor:
Ivana Halova, Pavel Tolar, Michael Boubelik, Lubica Dráberová, Petr Dráber, Martina Kovarova, Helena Cerná
Publikováno v:
Trends in Glycoscience and Glycotechnology. 13:261-279
Ligand- or antibody-mediated aggregation of surface receptors, such as antigen receptors on T cells, B cells and mast cells, induces signaling pathways resulting in diverse functional responses. Cell activation can also be initiated by aggregation of
Publikováno v:
Pharmacogenetics. 10:493-501
Quantitative aspects of the in-vitro interferon (IFN)-gamma-induced nitric oxide (NO) production by peritoneal macrophages of eight inbred strains of mice were investigated. Animals employed in the study can be assorted into three phenotype categorie
Publikováno v:
Biochemical and Biophysical Research Communications. 224:283-288
The oligosaccharide structure carried by embryoglycan, Lex hapten, as well as E-cadherin, has been described to mediate Ca(2+)-dependent cell-cell adhesions in embryonal carcinoma cells. To examine the contribution of these two systems to intercellul
Autor:
Vladimir, Bobek, Katarina, Kolostova, Daniela, Pinterova, Michael, Boubelik, Robert, Gurlich, Robert M, Hoffman
Publikováno v:
In vivo (Athens, Greece). 25(6)
Studies over the past decade have clearly shown that s.c. implant of primary and cultured tumor cells rarely leads to the occurrence of metastatic disease. Orthotopic transplantation of cell suspensions, surgical orthotopic implantation (SOI) of canc
Publikováno v:
Cancer investigation. 29(10)
Many studies have demonstrated the importance of spontaneous metastases in cancer research. Until now, we still had only a few spontaneous metastatic models with high occurrence rate of metastasis in distant lymph and visceral tissues. We report a sy