Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Michael Bogenstaetter"'
Autor:
Lisa Dvorak, Curt A. Dvorak, Curt Mazur, Kiev S. Ly, Michael Bogenstaetter, Jill A. Jablonowski, Brian Lord, Timothy W. Lovenberg, Jamin D. Boggs, Kirsten L. Miller, Nicholas I. Carruthers, Sandy J. Wilson
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:903-907
A novel series of imidazole containing histamine H3 receptor ligands were investigated and found to be potent functional antagonists. After improving the stability of these molecules towards liver microsomes, these compounds were found to have no app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c13fe402ebda266c7b30dd1d778341d
https://doi.org/10.1016/j.bmcl.2008.11.114
https://doi.org/10.1016/j.bmcl.2008.11.114
Publikováno v:
ChemInform. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::483151347484e2fb07555e681e3b2cf1
https://doi.org/10.1002/chin.200013150
https://doi.org/10.1002/chin.200013150
Autor:
Nicholas I. Carruthers, Doo Hyun Lee, Scott L. Dax, Curt Mazur, Nadia Nasser, Michele C. Jetter, Lisa Gonzales, Sui-Po Zhang, Michael Bogenstaetter, Swanson Devin M, Adrienne E. Dubin, Brian Lord, Michele C. Rizzolio, Ellen E. Codd, Sandra R. Chaplan, Chandra R. Shah, Leon Chang, J. Guy Breitenbucher, Changlu Liu, Kenway Hoey
Publikováno v:
Journal of medicinal chemistry. 48(6)
High throughput screening using the recombinant human TRPV1 receptor was used to identify a series of pyridinylpiperazine ureas (3) as TRPV1 vanilloid receptor ligands. Exploration of the structure-activity relationships by parallel synthesis identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df9cd9190a7eb6e6be5b677577b91b0f
https://pubmed.ncbi.nlm.nih.gov/15771431
https://pubmed.ncbi.nlm.nih.gov/15771431