Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Michael Bienert"'
Publikováno v:
Current Drug Delivery. 8:526-533
The ability of peptide nucleic acids (PNA) to enter and to cross filter-grown MDCK, HEK and CHO cells was studied by means of a protocol based on capillary electrophoresis combined with laser-induced fluorescence detection. The used approach avoided
Autor:
Eberhard Krause, Adel Ali Abdel-Maksoud, Holger Wenschuh, Ayman El-Faham, Michael Beyermann, Michael Bienert, Peter Henklein, Louis A. Carpino, Dumitru Ionescu, Khaled Nasr
Publikováno v:
Organic letters, 11(16): 3718–3721
The N-dicyclopropylmethyl (Dcpm) residue, introduced into amino acids via reaction of dicyclopropylmethanimine hydrochloride with an amino acid ester followed by sodium cyanoborohydride or triacetoxyborohydride reduction, can be used as an amide bond
Autor:
Michael Bienert, Eberhard Krause, Margitta Dathe, Michael Beyermann, Heinz Fabian, Sven Rothemund
Publikováno v:
International Journal of Peptide and Protein Research. 48:559-568
Among peptide secondary structures beta-sheet domains have been much less intensively studied than alpha-helical conformations, mainly because of the lack of well characterized model peptides. In the present paper the secondary structure of a water-s
Autor:
Peter Oehme, Burkhard Mehlis, Margitta Rueger, Michael Bienert, Manfred Becker, Hartmut Niedrich
Publikováno v:
International Journal of Peptide and Protein Research. 15:20-28
CD spectra of substance P (SP) and its C-terminal partial sequences have been measured in diluted aqueous solution including variation of hydrogen ion concentration. In the far u.v. region there is an overlapping of the amide CD absorption by the CD
Publikováno v:
The Journal of Peptide Research. 50:184-192
Multiple peptide synthesis has been applied for the simultaneous synthesis of systematic replacement sets of model peptides which varied in length from 18 to 36 residues and ovine corticotropin-releasing hormone (oCRH), a 41-residue receptor-binding
Publikováno v:
International Journal of Peptide and Protein Research. 41:207-211
The instability of the undecapeptide substance P (SP), a neuropeptide implicated in several physiological processes, was occasionally observed when the peptide was stored in the solid state or in solution. The aim of the present study was to identify
Publikováno v:
Journal of Neurochemistry. 62:2246-2253
Substance P (SP) and SP analogues, including C-terminal, N-terminal, and C-terminus-extended analogues, have been investigated for their ability to modulate nicotine-induced secretion from bovine adrenal chromaffin cells in culture. Secretion was mon
Autor:
Sven Rothemund, Michael Bienert, Michael Beyermann, Stephan Pritz, Annerose Klose, Jana Klose, K. Fechner, Oliver Kraetke
Publikováno v:
Angewandte Chemie. 120:3698-3701
Publikováno v:
Nature Protocols. 2:3247-3256
This protocol for solid-phase peptide synthesis (SPPS) is based on the widely used Fmoc/tBu strategy, activation of the carboxyl groups by aminium-derived coupling reagents and use of PEG-modified polystyrene resins. A standard protocol is described,