Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Michael Biddle"'
Autor:
Abdulrahman Alzahrani, Jameel Hakeem, Michael Biddle, Fahad Alhadian, Aamir Hussain, Latifa Khalfaoui, Katy M. Roach, Omar Tliba, Peter Bradding, Yassine Amrani
Publikováno v:
Frontiers in Allergy, Vol 2 (2021)
The mechanisms underlying corticosteroid insensitivity in severe asthma have not been elucidated although some indirect clinical evidence points toward a role of mast cells. Here, we tested the hypothesis that mast cells can drive corticosteroid inse
Externí odkaz:
https://doaj.org/article/2d6cc5806c3343ea905d61faa697cb69
Autor:
Renee Robinson, Cara Liday, Anushka Burde, Tracy Pettinger, Amy Paul, Elaine Nguyen, John Holmes, Megan Penner, Angela Jaglowicz, Nathan Spann, Julia Boyle, Michael Biddle, Brooke Buffat, Kevin Cleveland, Brecon Powell, Christopher Owens
Publikováno v:
Pharmacy, Vol 8, Iss 3, p 120 (2020)
Evidence-based interventions have been shown to improve the quality of patient care, reduce costs, and improve overall health outcomes; however, adopting new published research and knowledge into practice has historically been slow, and requires an a
Externí odkaz:
https://doaj.org/article/37a5cc4b5ae149618e6dde69ad21db97
Publikováno v:
Free Radical Biology and Medicine. 185:97-119
The airway smooth muscle (ASM) surrounding the airways is dysfunctional in both asthma and chronic obstructive pulmonary disease (COPD), exhibiting; increased contraction, increased mass, increased inflammatory mediator release and decreased corticos
Autor:
Michael Biddle, Dawn T. Smallwood, E Castells, Peter Bradding, Katy M. Roach, Cathryn Weston, Yassine Amrani, Viona W. Bowman, Harvinder Virk, Jamie McCarthy, S. Mark Duffy
Publikováno v:
British Journal of Pharmacology. 178:2948-2962
BACKGROUND AND PURPOSE TGFβ1-mediated myofibroblast activation contributes to pathological fibrosis in many diseases including idiopathic pulmonary fibrosis (IPF), where myofibroblast resistance to oxidant-mediated apoptosis is also evident. We ther
Autor:
Brittany, Romans, Elaine, Nguyen, Michael, Biddle, Amy, Paul, Zach, Rosko, Ashley, Minaei, Thomas, Wadsworth, Renee F, Robinson
Publikováno v:
Journal of allied health. 51(1)
In the United States, healthcare providers document and code healthcare encounters and submit claims to insurers for reimbursement. Most providers eligible for individual-level insurer reimbursement do not receive coding/billing training. The purpose
Autor:
Omar Tliba, Latifa Chachi, Jameel Hakeem, Peter Bradding, Fahad Alhadian, Yassine Amrani, Michael Biddle
Publikováno v:
Airway pharmacology and treatment.
Autor:
Michael Biddle, Adam K. A. Wright, Peter Bradding, David J. Cousins, Harvinder Virk, Katy M. Roach, Yassine Amrani, Cate Weston, Malgorzata Rekas
Publikováno v:
Airway cell biology and immunopathology.
Autor:
Adam K. A. Wright, Latifa Chachi, Katy M. Roach, Peter Bradding, J. Sousa, Michael Biddle, Cathryn Weston, Harvinder Virk, M. Z. Rekas
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
The transient receptor potential cation channel family member ankyrin 1 (TRPA1) is a potential target for several diseases, but detection of human TRPA1 (hTRPA1) protein in cells and tissues is problematic as rigorous antibody validation is lacking.
Autor:
Himanshu Kaul, Amanda Sutcliffe, Ian D. Pavord, Sherif Gonem, Bindi S. Brook, Rod Smallwood, Davinder Kaur, Andrew J. Wardlaw, Latifa Chachi, Michelle Bourne, Christopher E. Brightling, Amisha Singapuri, Richard Kay, Ruth Saunders, Salman Siddiqui, Rachid Berair, Michael Biddle
Publikováno v:
Science Translational Medicine. 11(479)
Increased airway smooth muscle mass, a feature of airway remodeling in asthma, is the strongest predictor of airflow limitation and contributes to asthma-associated morbidity and mortality. No current drug therapy for asthma is known to affect airway
Autor:
Peter Bradding, Latifa Chachi, Yassine Amrani, Reynold A. Panettieri, Cynthia Koziol-White, Abdulrahman Alzahrani, Michael Biddle, Rehab Bagadood
Publikováno v:
Clinical and experimental immunology. 194(2)
Summary The purpose of this study was to investigate whether growth factors produced by activated human lung mast cells (HLMCs) impair β2-adrenoceptor (β2-AR) function in human airway smooth muscle (ASM) cells. Protein array analysis confirmed the