Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Michael Betenbaugh"'
Publikováno v:
mSystems, Vol 9, Iss 11 (2024)
ABSTRACT Bacillus subtilis is an important industrial and environmental microorganism known to occupy many niches and produce many compounds of interest. Although it is one of the best-studied organisms, much of this focus including the reconstructio
Externí odkaz:
https://doaj.org/article/a9e98b6b2d964406bac08836524fb9d6
Autor:
Jenny M. Lee, Alexis Figueroa, Jaiprasath Sachithanandham, Maggie Li, Caoilfhionn M. Connolly, Janna R. Shapiro, Yiqun Chen, Michelle Jones, Venkata Gayatri Dhara, Marilyn Towns, John S. Lee, Stephanie R. Peralta, Aaron M. Milstone, Michael Betenbaugh, Amanda K. Debes, Joel Blankson, Ioannis Sitaras, Steve Yoon, Elizabeth A. Thompson, Clifton O. Bingham, Sabra L. Klein, Andrew Pekosz, Justin R. Bailey
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Patients with inflammatory arthritis (IA) are at increased risk of severe COVID-19 due to medication-induced immunosuppression that impairs host defenses. The aim of this study was to assess antibody and B cell responses to COVID-19 mRNA vaccination
Externí odkaz:
https://doaj.org/article/1ec2cd452f3f47fe824a3fbe8bc7e429
Autor:
Steve Huhn, Meiping Chang, Amit Kumar, Ren Liu, Bo Jiang, Michael Betenbaugh, Henry Lin, Gregg Nyberg, Zhimei Du
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104074- (2022)
Summary: Genetic instability of Chinese hamster ovary (CHO) cells is implicated in production inconsistency through poorly defined mechanisms. Using a multi-omics approach, we analyzed the variations of CHO lineages derived from CHO-K1 cells. We iden
Externí odkaz:
https://doaj.org/article/7cea1391b1c1462189adca184eb35fe2
Autor:
Itrat Zahra, Ayesha Liaqat, Michael Betenbaugh, Uzma Ramzan, Khaled Elmnasri, Amor Hedfi, Manel Ben Ali, Bander Albogami, Farah R Shakoori, Abdul R Shakoori
Publikováno v:
Materials Research Express, Vol 10, Iss 3, p 035403 (2023)
The introduction of heavy metals by industries in the aquatic ecosystem is a threatening alarm for living organisms. Bioremediation is an eco-friendly and inexpensive technique as an alternative to chemical methods for wastewater treatment. Wastewate
Externí odkaz:
https://doaj.org/article/f8594e2efb38495faa59f583d31e70ff
Autor:
Ganglong Yang, Naseruddin Höti, Shao-Yung Chen, Yangying Zhou, Qiong Wang, Michael Betenbaugh, Hui Zhang
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Recently, the glycoproteomic analysis of intact glycopeptides has emerged as an effective approach to decipher the glycan modifications of glycoproteins at the site-specific level. A rapid method to enrich intact glycopeptides is essential for the an
Externí odkaz:
https://doaj.org/article/ca98a11d481f44b696a8465def3cdc05
Researchers and engineers came together in Lisbon at the 27 Meeting of the European Society for Animal Cell Technology (ESACT 2022), to discuss the latest advances in technologies associated with protein-based biologics production, new modalities and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18002a470187cc80aec46652a6985ba6
https://doi.org/10.22541/au.168537786.66549748/v1
https://doi.org/10.22541/au.168537786.66549748/v1
Autor:
Lauren T. Cordova, Hussain Dahodwala, Kathryn S. Elliott, Jongyoun Baik, Daniel C. Odenewelder, Douglas Nmagu, Bradley A. Skelton, Lisa Uy, Stephanie R. Klaubert, Benjamin F. Synoground, Dylan G. Chitwood, Venkata Gayatri Dhara, Harnish Mukesh Naik, Caitlin S. Morris, Seongkyu Yoon, Michael Betenbaugh, Jon Coffman, Frank Swartzwelder, Michael P. Gillmeister, Sarah W. Harcum, Kelvin H. Lee
Publikováno v:
Biotechnology and bioengineeringREFERENCES.
Due to the favorable attributes of Chinese hamster ovary (CHO) cells for therapeutic proteins and antibodies biomanufacturing, companies generate proprietary cells with desirable phenotypes. One key attribute is the ability to stably express multi-gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b57544b52ac58fe499c41499dcc9c0
https://pubmed.ncbi.nlm.nih.gov/36411514
https://pubmed.ncbi.nlm.nih.gov/36411514
The use of transposase in cell line development (CLD) programs has experienced increased popularity over the past decade. However, few studies have described the mechanism of action and the genomic and phenotypic characteristics of clones derived fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84c4852a676730d10202d3100c08b7c5
https://doi.org/10.22541/au.165816370.02613398/v1
https://doi.org/10.22541/au.165816370.02613398/v1
Autor:
Swetha Kumar, Amit Kumar, Steven Huhn, Lauren DeVine, Robert Cole, Zhimei Du, Michael Betenbaugh
Publikováno v:
Biotechnology and bioengineering. 119(8)
Chinese hamster ovary (CHO) cells serve as protein therapeutics workhorses, so it is useful to understand what intrinsic properties make certain host cell lines and clones preferable for scale up and production of target proteins. In this study, two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7428272f785f98a2231c29baaf9a5550
https://pubmed.ncbi.nlm.nih.gov/35470426
https://pubmed.ncbi.nlm.nih.gov/35470426
Publikováno v:
Biotechnology and bioengineeringREFERENCES. 119(5)
The CDK4/6 inhibitor has been shown to increase recombinant protein productivity in Chinese hamster ovary (CHO) cells. Therefore, we investigated the mechanism that couples cell-cycle inhibitor (CCI) treatment with protein productivity utilizing prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0079ae6b8e16ef531b47a4a3f261f0d
https://pubmed.ncbi.nlm.nih.gov/35112712
https://pubmed.ncbi.nlm.nih.gov/35112712