Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Michael Beaupre"'
Autor:
Ankita Singh, Michael Beaupre, Cecilia Villegas-Novoa, Kiyoshi Shiomitsu, Stephen J. Gaudino, Suzanne Tawch, Ruhee Damle, Cody Kempen, Biswa Choudhury, Jeremy P. McAleer, Brian S. Sheridan, Paula Denoya, Richard S. Blumberg, Patrick Hearing, Nancy L. Allbritton, Pawan Kumar
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114643- (2024)
Externí odkaz:
https://doaj.org/article/32662145e22e43dabd726659479069cc
Autor:
Preet Joshi, Cody Kempen, Stephen J. Gaudino, Onur Eskiocak, Sonika Rathi, Pawan Kumar, Xun Lin, Kenneth R. Shroyer, Neil Mehta, Brian Yueh, Patrick A. McLaughlin, Semir Beyaz, Adrianus W. M. van der Velden, Michael Beaupre, Agnieszka B. Bialkowska, Richard S. Blumberg
Publikováno v:
Mucosal Immunology
Interleukin-22 (IL-22) signaling in the intestines is critical for promoting tissue-protective functions. However, since a diverse array of cell types (absorptive and secretory epithelium as well as stem cells) express IL-22Ra1, a receptor for IL-22,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27343370b62a5de94207b3442893996e
https://doi.org/10.1038/s41385-020-00348-5
https://doi.org/10.1038/s41385-020-00348-5
Autor:
Xun Lin, Stephen J. Gaudino, Kyung Ku Jang, Tej Bahadur, Ankita Singh, Anirban Banerjee, Michael Beaupre, Timothy Chu, Hoi Tong Wong, Chang-Kyung Kim, Cody Kempen, Jordan Axelrad, Huakang Huang, Saba Khalid, Vyom Shah, Onur Eskiocak, Olivia B. Parks, Artan Berisha, Jeremy P. McAleer, Misty Good, Miko Hoshino, Richard Blumberg, Agnieszka B. Bialkowska, Sarah L. Gaffen, Jay K. Kolls, Vincent W. Yang, Semir Beyaz, Ken Cadwell, Pawan Kumar
Publikováno v:
Immunity
The Th17 cell lineage-defining cytokine IL-17A contributes to host defense and inflammatory disease by coordinating multicellular immune responses. The IL-17 receptor (IL-17RA) is expressed by diverse intestinal cell types, and therapies targeting IL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd325755d8dbab484bedca0ec2aae2cf
https://europepmc.org/articles/PMC8895883/
https://europepmc.org/articles/PMC8895883/
Autor:
Preet Joshi, Stephen J. Gaudino, Huakang Huang, Cody Kempen, Makheni Jean-Pierre, Hoi Tong Wong, Pawan Kumar, Michael Beaupre
Publikováno v:
J Immunol
Previous studies indicate that IL-17A plays an important role in mediating the intestinal microbiota and systemic metabolic functions. However, it is not known where IL-17RA signaling occurs to mediate these effects. To investigate this question, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc99b224c71f489e9e125405fbec39c
https://europepmc.org/articles/PMC8556717/
https://europepmc.org/articles/PMC8556717/
Publikováno v:
The Journal of Immunology. 208:108.17-108.17
Interleukin-22 plays both beneficial and deleterious role in intestinal inflammation. Further investigation is required to understand cell target and mechanism of action of IL-22 in large intestine. By using various intestinal cell specific IL-22Ra1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::250df7e74c4fbe7148891bd76a21cc5a
https://doi.org/10.4049/jimmunol.208.supp.108.17
https://doi.org/10.4049/jimmunol.208.supp.108.17
Autor:
Stephen Gaudino, Michael Beaupre, Xun Lin, Sonika Rathi, Patrick McLaughlin, Neil Mehta, Onur Eskiocak, Brian Yueh, Adrianus Van der Velden, Semir Beyaz, Pawan Kumar
Publikováno v:
The Journal of Immunology. 204:60.9-60.9
Interleukin-22 (IL-22) acts in the intestine to promote critical tissue protective functions. However, since a diverse array of intestinal cell types (absorptive, secretory, and stem cells) express IL-22Ra1, a receptor for IL-22, it has been difficul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a328b568fb6268487c5a3a147e755fc
https://doi.org/10.4049/jimmunol.204.supp.60.9
https://doi.org/10.4049/jimmunol.204.supp.60.9
Publikováno v:
The Journal of Immunology. 202:181.11-181.11
Impaired signaling by IL-22 has been shown to accelerate high fat diet (HFD)-induced obesity. However, it is not known if IL-22 signaling in the intestine regulates HFD-induced metabolic disorders. To test this, intestinal epithelial-specific IL-22RA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11870cf5c303bb1618dbcf8324f6c521
https://doi.org/10.4049/jimmunol.202.supp.181.11
https://doi.org/10.4049/jimmunol.202.supp.181.11
Publikováno v:
Volume 2: Pipeline Safety Management Systems; Project Management, Design, Construction and Environmental Issues; Strain Based Design; Risk and Reliability; Northern Offshore and Production Pipelines.
In the last 5 years in Canada, regulators have been requesting that new pipeline projects provide quantitative risk management of all credible geohazards involving the proposed pipeline corridor so it can be demonstrated that geohazards are being rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3f9088555e4ea941d80a59d5a3dff14
https://doi.org/10.1115/ipc2016-64580
https://doi.org/10.1115/ipc2016-64580