Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Michael B. Widmer"'
Autor:
Hafez Golzarian, Morgan Turnow, Sidney Elston, Pavithra Kannan, Shudipan Chakraborty, Michael B. Widmer, Sulayman Mughal, Salar Kohan, Michael Nguyen, Joseph F. Sabik, Sandeep M. Patel
Publikováno v:
JTCVS Techniques.
Publikováno v:
European Heart Journal - Case Reports. 7
Autor:
Henry J. Winn, Hugh Auchincloss, Laurie H. Glimcher, Terri M. Laufer, Michael B. Widmer, Marc S. Sabatine
Publikováno v:
Transplantation. 65:113-120
Background Exogenous soluble tumor necrosis factor receptor (TNFR) has been shown to be an effective immunosuppressant. It has yet to be tested whether tissues secreting soluble TNFR, when transplanted into a foreign host, could locally generate immu
Publikováno v:
Transplantation. 62:636-642
In earlier studies, we showed that a 14-day continuous subcutaneous infusion of recombinant human interleukin (IL)-1 accelerated neutrophil recovery and enhanced long-term chimerism in a bone marrow (BM) transplant model in which T-cell-depleted BALB
Autor:
Bruce R. Blazar, Daniel J. Weisdorf, Angela Panoskaltsis-Mortari, Michael B. Widmer, Zhiyi Xu, Emmanuel Katsanis
Publikováno v:
Transplantation. 62:872-875
The toxicity and antitumor efficacy of simian IL-15 was compared with human IL-2 in the context of syngeneic BMT. Groups of mice receiving or not receiving anti-CD3 activated splenocytes, termed T-activated killer (T-AK) cells, were treated between d
Autor:
James D. Eason, Siewlin Wee, Tatsuo Kawai, Han Zhou Hong, John A. Powelson, Michael B. Widmer, A. Benedict Cosimi
Publikováno v:
Transplantation. 59:300-305
Publikováno v:
Blood. 80:1614-1622
Irradiated C57BL/6 (H-2b) recipients of T-cell-depleted (TCD) BALB/c (H- 2d) bone marrow (BM) and recombinant interleukin-1 alpha (IL-1 alpha) (1 microgram/d) had a significantly (P less than or equal to .006) higher 100-day actuarial survival rate,
Autor:
Michael B. Widmer
Publikováno v:
Current Opinion in Biotechnology. 2:872-876
Multiple lines of evidence implicate cytokines in the pathogenesis of autoimmune and inflammatory diseases. Neutralization of the biological activities of cytokines by interfering with ligand binding to specific cell-surface cytokine receptors thus r
Autor:
Jeffrey A. Ledbetter, Edward A. Clark, Mary A. Valentine, Michael B. Widmer, David L. Brautigan, Fran M. Pinault, Robert F. Voice, Byron M. Gallis
Publikováno v:
European Journal of Immunology. 21:913-919
Ligation of interleukin 2 (IL2) is known to regulate both protein tyrosine and serine/threonine phosphorylation. A family of leukocyte transmembrane proteins whose cytoplasmic domain exhibits intrinsic protein tyrosine phosphatase activity is collect
Autor:
Takuji, Naka, Kenji, Sugamura, Bonnie L, Hylander, Michael B, Widmer, Youcef M, Rustum, Elizabeth A, Repasky
Publikováno v:
Cancer research. 62(20)
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has been reported to induce apoptosis in a variety of malignant cell lines, but it shows little or no toxicity in most normal cells. We examined the response of three human colon tumors