Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Michael B. Sano"'
Autor:
Chris C. Fesmire, Bridgette Peal, Jennifer Ruff, Elizabeth Moyer, Thomas J. McParland, Kobi Derks, Erin O’Neil, Carrie Emke, Brianna Johnson, Shatorupa Ghosh, Ross A. Petrella, Matthew R. DeWitt, Timo Prange, Callie Fogle, Michael B. Sano
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
IntroductionIntegrated time nanosecond pulse irreversible electroporation (INSPIRE) is a novel tumor ablation modality that employs high voltage, alternating polarity waveforms to induce cell death in a well-defined volume while sparing the underlyin
Externí odkaz:
https://doaj.org/article/8a839b0513b54072a7eafa1804829e78
Publikováno v:
IEEE Transactions on Biomedical Engineering. 69:2353-2362
Expanding the volume of an irreversible electroporation treatment typically necessitates an increase in pulse voltage, number, duration, or repetition. This study investigates the addition of polyethylenimine nanoparticles (PEI-NP) to pulsed electric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b748fe4fb2533ce0759c79e338e13d5
https://doi.org/10.1109/tbme.2022.3143084
https://doi.org/10.1109/tbme.2022.3143084
Publikováno v:
Annals of Biomedical Engineering. 49:191-202
Thermal tissue injury is an unintended consequence in current irreversible electroporation treatments due to the induction of Joule heating during the delivery of high voltage pulsed electric fields. In this study active temperature control measures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75c4d327459b05fc9d6f8b75e90b3e5e
https://doi.org/10.1007/s10439-020-02524-x
https://doi.org/10.1007/s10439-020-02524-x
Autor:
Michael B. Sano, Matthew R. DeWitt
Publikováno v:
Bioelectricity
Background: Irreversible electroporation (IRE) induces cell death through nonthermal mechanisms, however, in extreme cases, the treatments can induce deleterious thermal transients. This study utilizes a thermochromic tissue phantom to enable visuali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88f9e3c974901f8ba1b82337d70e62b2
https://pubmed.ncbi.nlm.nih.gov/34476365
https://pubmed.ncbi.nlm.nih.gov/34476365
Publikováno v:
Bioelectrochemistry (Amsterdam, Netherlands). 135
Irreversible electroporation (IRE) is generally considered to be a non-thermal ablation modality. This study was designed to examine the relative effect of temperature on IRE ablation sizes for equivalent dose treatments with constitutive pulses betw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba5bd3283b4d57e8759ab093582117f
https://pubmed.ncbi.nlm.nih.gov/32438309
https://pubmed.ncbi.nlm.nih.gov/32438309
Publikováno v:
Computers in Biology and Medicine. 95:107-117
High-frequency irreversible electroporation (H-FIRE) is an emerging ablation modality, delivering rapid bursts of bipolar microsecond-duration electrical pulses to non-thermally ablate tissue including tumors. With advantages over current electropora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::972161e41ce1ec1174169f339f612cf7
https://doi.org/10.1016/j.compbiomed.2018.02.009
https://doi.org/10.1016/j.compbiomed.2018.02.009
Publikováno v:
Annals of Biomedical Engineering. 45:2524-2534
Several focal therapies are being investigated clinically to treat tumors in which surgery is contraindicated. Many of these ablation techniques, such as radiofrequency ablation and microwave ablation, rely on thermal damage mechanisms which can put
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a55924627fa9b0d54e9390c9f00197e0
https://doi.org/10.1007/s10439-017-1889-2
https://doi.org/10.1007/s10439-017-1889-2
Publikováno v:
Annals of biomedical engineering. 49(1)
Thermal tissue injury is an unintended consequence in current irreversible electroporation treatments due to the induction of Joule heating during the delivery of high voltage pulsed electric fields. In this study active temperature control measures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c130064bfa4ea4613d28e251ec0c8a1d
https://pubmed.ncbi.nlm.nih.gov/32415482
https://pubmed.ncbi.nlm.nih.gov/32415482
Autor:
David A. Gerber, Callie A. Fogle, Michael B. Sano, Jacob D. Kaufman, Christopher C. Fesmire, Ross A. Petrella, Lei Xing
Publikováno v:
Computers in biology and medicine. 121
Electro-thermal therapy (ETT) is a new cancer treatment modality which combines the use of high voltage pulsed electric fields, dynamic energy delivery rates, and closed loop thermal control algorithms to rapidly and reproducibly create focal ablatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b35f2b32a0e6c7581325858cd3074413
https://pubmed.ncbi.nlm.nih.gov/32568680
https://pubmed.ncbi.nlm.nih.gov/32568680
Autor:
Ross A. Petrella, Christopher C. Fesmire, Lei Xing, David A. Gerber, Callie A. Fogle, Michael B. Sano
Publikováno v:
Annals of biomedical engineering. 48(8)
Electroporation is a bioelectric phenomenon used to deliver target molecules into cells in vitro and irreversible electroporation (IRE) is an emerging cancer therapy used to treat inoperable tumors in situ. These phenomena are generally considered to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::736c47339cf69c5c132ec9e23f7913a6
https://pubmed.ncbi.nlm.nih.gov/32409902
https://pubmed.ncbi.nlm.nih.gov/32409902