Výsledky vyhledávání - "Michael B. Maddock"

Cytogenetics of the elasmobranchs: genome evolution and phylogenetic implications

Autor: Michael B. Maddock, Frank J. Schwartz

Publikováno v: Marine and Freshwater Research. 53:491

Colcemid-treated blood sampling methods permitted conventional cytogenetic studies of elasmobranch karyotypes. Representatives were karyotyped from the superorders: Galeomorphii (4 orders), Squalomorphii (3 orders), Squatinomorphii (1 genus), and Bat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::12548f7edcc4e5929c5868f59bc6933c
https://doi.org/10.1071/mf01139

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Activation and detoxication of promutagens by toadfish (Opsanus tau) hepatic postmitochondrial fractions in the Salmonella assay

Autor: Deborah M. Milling, Michael B. Maddock

Publikováno v: Mutation Research/Environmental Mutagenesis and Related Subjects. 164:81-89

Three groups of experiments were conducted to characterize the hepatic postmitochondrial fraction (S9) from the oyster toadfish ( Opsanus tau ) as an activation system for promutagens in the Salmonella assay and to provide an initial evaluation of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee61d8ac0580afc7ab130983a725608
https://doi.org/10.1016/0165-1161(86)90046-4

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In vitro induction of sister chromatid exchanges and chromosomal aberrations in peripheral lymphocytes of the oyster toadfish and american eel

Autor: Tara J. Ellingham, Michael B. Maddock, Elizabeth A. Christensen

Publikováno v: Environmental Mutagenesis. 8:555-569

A series of experiments was conducted to characterize the proliferation of oyster toadfish lymphocytes in medium containing 5-bromodeoxyuridine (BrdUrd) and to determine the effectiveness of cytogenetic endpoints for assessing the genotoxic effects o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13eaeb1fc8cd6bc32f98976cdd6da222
https://doi.org/10.1002/em.2860080407

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Significance of multiparameter flow cytometric analysis of ovarian cancer

Autor: David H. Moore, Stephen Haskill, Wesley C. Fowler, Michael B. Maddock

Publikováno v: American Journal of Obstetrics and Gynecology. 158:838-843

A prospective flow cytometric examination of ovarian epithelial tumors was undertaken to further characterize aneuploid (including triploid and tetraploid) tumor cell populations according to expression of ovarian tumor antigen CA125 and to expressio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46d2989a8c9b032e8449da6f52dcbfeb
https://doi.org/10.1016/0002-9378(88)90081-6

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Artificial insemination of deermice (Peromyscus maniculatus) with sperm from other rodent species

Autor: Wallace D. Dawson, Michael B. Maddock

Publikováno v: Development. 31:621-634

Deermice (Peromyscus maniculatus) were hormonally induced to ovulate and artificially inseminated with sperm of 13 other rodent species varying in taxonomic distinction from species to family level. These were compared with inter se and sham insemina

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bc183cb55f24fd88d5acf49822c3b56c
https://doi.org/10.1242/dev.31.3.621

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Activation of polycyclic aromatic hydrocarbons by hepatic S-9 from a marine fish

Autor: Michael B. Maddock, Deborah M. Milling

Publikováno v: Bulletin of Environmental Contamination and Toxicology. 35:301-307

This paper reports initial efforts to characterize the in vitro metabolism of several weakly carcinogenic and non-carcinogenic (in mammals) PAH's by hepatic S-9 preparations from the oyster toadfish (Opsanus tau) to Salmonella mutagens. The objective

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1221df569b6a6599d48d669f49796767
https://doi.org/10.1007/bf01636514

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The effects of pretreatment with cytochrome P-450 inducers and preincubation with a cytochrome P-450 effector on the mutagenicity of genotoxic carcinogens mediated by hepatic and renal S9 from two species of marine fish

Autor: Tara J. Ellingham, Michael B. Maddock, Richard J. Guobaitis

Publikováno v: Mutation Research/Environmental Mutagenesis and Related Subjects. 164:59-70

A series of experiments was designed to characterize the cytochrome P-450-dependent activation of 7 genotoxic carcinogens in the Salmonella preincubation assay by hepatic postmitochondrial fractions (S9) from the oyster toadfish and the Americal eel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ef95dd88abe69eb25bad9f12c3260b
https://doi.org/10.1016/0165-1161(86)90042-7

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In vitro induction of unscheduled DNA synthesis by genotoxic carcinogens in the hepatocytes of the oyster toadfish (Opsanus tau)

Autor: Michael B. Maddock, Janet J. Kelly

Publikováno v: Archives of environmental contamination and toxicology. 14(5)

The possibility that the measurement of unscheduled DNA synthesis (UDS) can be used to investigate the genotoxic effects of mutagenic carcinogens in a marine fish was examined. Primary cultures of hepatocytes from the oyster toadfish (Opsanus tau) we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae5493f1006e64a2311506c093c3637f
https://pubmed.ncbi.nlm.nih.gov/4051568

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