Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Michael B. Cole"'
Autor:
Enrique Martin-Gayo, Michael B. Cole, Kellie E. Kolb, Zhengyu Ouyang, Jacqueline Cronin, Samuel W. Kazer, Jose Ordovas-Montanes, Mathias Lichterfeld, Bruce D. Walker, Nir Yosef, Alex K. Shalek, Xu G. Yu
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-21 (2018)
Abstract Background Human immunity relies on the coordinated responses of many cellular subsets and functional states. Inter-individual variations in cellular composition and communication could thus potentially alter host protection. Here, we explor
Externí odkaz:
https://doaj.org/article/49d6cbdd74584883a09c5c667e8590f0
Publikováno v:
Proceedings of the Entomological Society of Washington. 124
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef69b5a37cabca5d8f8d8dc1e1b28506
https://doi.org/10.4289/0013-8797.124.1.131
https://doi.org/10.4289/0013-8797.124.1.131
Publikováno v:
Proceedings of the Entomological Society of Washington. 123
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2aabb1e92ee679a4c0731f24623a50e4
https://doi.org/10.4289/0013-8797.123.4.852
https://doi.org/10.4289/0013-8797.123.4.852
Publikováno v:
Nature methods
Nature methods, vol 15, iss 12
Nature methods, vol 15, iss 12
Transcriptome measurements of individual cells reflect unexplored biological diversity, but are also affected by technical noise and bias. This raises the need to model and account for the resulting uncertainty in any downstream analysis. Here, we in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ac3507eea61f1fb1831d4254043836
http://europepmc.org/articles/PMC6289068
http://europepmc.org/articles/PMC6289068
Autor:
Alice Baker, Michael B. Cole, Kimberly E. Taylor, Diana Quach, Hong Quach, Lisa F. Barcellos, Lindsey A. Criswell
Publikováno v:
Arthritis & Rheumatology. 68:2936-2944
Objective Sjogren's syndrome (SS) is a complex multisystem autoimmune disease that results in progressive destruction of the exocrine glands. The purpose of this study was to characterize epigenetic changes in affected gland tissue and describe the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aff9416137fb80a44b9403471d792570
https://doi.org/10.1002/art.39792
https://doi.org/10.1002/art.39792
Autor:
Sandrine Dudoit, David DeTomaso, Allon Wagner, Elizabeth Purdom, Davide Risso, Nir Yosef, Michael B. Cole, John Ngai
Publikováno v:
Cell systems, vol 8, iss 4
Systematic measurement biases make data normalization an essential preprocessing step in single-cell RNA sequencing (scRNA-seq) analysis. There may be multiple, competing considerations behind the assessment of normalization performance, some of them
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d624b7083d1e71fc3ee7c7e6859c9cc
https://pubmed.ncbi.nlm.nih.gov/31022373
https://pubmed.ncbi.nlm.nih.gov/31022373
Transcriptome profiles of individual cells reflect true and often unexplored biological diversity, but are also affected by noise of biological and technical nature. This raises the need to explicitly model the resulting uncertainty and take it into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86fbde34af5fa52966cc005aeda60ad1
Autor:
Kellie E. Kolb, Samuel W. Kazer, Mathias Lichterfeld, Michael B. Cole, Bruce D. Walker, Jacqueline Cronin, Enrique Martin-Gayo, Jose Ordovas-Montanes, Nir Yosef, Zhengyu Ouyang, Alex K. Shalek, Xu G. Yu
Publikováno v:
BioMedCentral
Genome Biology
BioMed Central
Genome biology, vol 19, iss 1
Genome Biology, Vol 19, Iss 1, Pp 1-21 (2018)
Genome Biology
BioMed Central
Genome biology, vol 19, iss 1
Genome Biology, Vol 19, Iss 1, Pp 1-21 (2018)
BACKGROUND: Human immunity relies on the coordinated responses of many cellular subsets and functional states. Inter-individual variations in cellular composition and communication could thus potentially alter host protection. Here, we explore this h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::320d1c9fe20b5fe6a50beb01e9bad099
http://hdl.handle.net/1721.1/113421
http://hdl.handle.net/1721.1/113421
Autor:
Quetzal Flores, Michael B. Cole, Sandrine Dudoit, Diya Das, John Ngai, Davide Risso, Kelly Street, Levi Gadye, Yoon Gi Choi, Russell B. Fletcher, Nir Yosef, Ariane Baudhuin, Elizabeth Purdom, Allon Wagner
Publikováno v:
Cell stem cell, vol 20, iss 6
A detailed understanding of the paths that stem cells traverse to generate mature progeny is vital for elucidating the mechanisms governing cell fate decisions and tissue homeostasis. Adult stem cells maintain and regenerate multiple mature cell line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54855e470c9da1dbfbff899c6d9cc604
http://hdl.handle.net/11577/3280593
http://hdl.handle.net/11577/3280593
Autor:
Diya Das, Russell B. Fletcher, Levi Gadye, Kelly Street, John Ngai, Yoon Gi Choi, Sandrine Dudoit, Ariane Baudhuin, Michael B. Cole, Davide Risso, Nir Yosef, Elizabeth Purdom, Allon Wagner, Michael A. Sanchez
Publikováno v:
Cell Stem Cell. 21:775-790.e9
Tissue homeostasis and regeneration are mediated by programs of adult stem cell renewal and differentiation. However, the mechanisms that regulate stem cell fates under such widely varying conditions are not fully understood. Using single-cell techni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fdedfdc6cafc5e25e689239bac6bcea
https://doi.org/10.1016/j.stem.2017.10.014
https://doi.org/10.1016/j.stem.2017.10.014