Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Michael B. Chabot"'
Publikováno v:
Journal of physical organic chemistry. 35(11)
Fluorescent dyes are routinely used to visualize DNA or RNA in various experiments, and some dyes also act as photosensitizers capable of catalyzing oxidation reactions. The present studies explored whether the common labeling dyes fluorescein, rhoda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81773a8883263a8e74ac68fac510a132
https://pubmed.ncbi.nlm.nih.gov/36388261
https://pubmed.ncbi.nlm.nih.gov/36388261
Publikováno v:
The Journal of Organic Chemistry. 87:11865-11870
Exposure of DNA to oxidants results in modification of the electron-rich guanine heterocycle including formation of the mutagenic 5-carboxamido-5-formamido-2-iminohydantoin (2Ih) lesion. Previously thought to exist solely as a pair of diastereomers,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0bb4811158ab38cf2c8ed49df5a55da
https://doi.org/10.1021/acs.joc.2c01371
https://doi.org/10.1021/acs.joc.2c01371
Publikováno v:
Angew Chem Int Ed Engl
Nucleic acids are chemically modified to fine-tune their properties for biological function. Chemical tools for selective tagging of base modifications enables new approaches; the photosensitizers riboflavin and anthraquinone were previously proposed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71ed6b7a6db616bf56cea2207993fab2
https://doi.org/10.1002/anie.202110649
https://doi.org/10.1002/anie.202110649