Zobrazeno 1 - 10
of 178
pro vyhledávání: '"Michael B Fessler"'
Autor:
Nathaniel MacNell, Lydia Feinstein, Jesse Wilkerson, Pӓivi M Salo, Samantha A Molsberry, Michael B Fessler, Peter S Thorne, Alison A Motsinger-Reif, Darryl C Zeldin
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0280387 (2023)
Despite the prominent use of complex survey data and the growing popularity of machine learning methods in epidemiologic research, few machine learning software implementations offer options for handling complex samples. A major challenge impeding th
Externí odkaz:
https://doaj.org/article/b33f611be50144cfb463297b797ed985
Autor:
Salik Hussain, Collin G Johnson, Joseph Sciurba, Xianglin Meng, Vandy P Stober, Caini Liu, Jaime M Cyphert-Daly, Katarzyna Bulek, Wen Qian, Alma Solis, Yosuke Sakamachi, Carol S Trempus, Jim J Aloor, Kym M Gowdy, W Michael Foster, John W Hollingsworth, Robert M Tighe, Xiaoxia Li, Michael B Fessler, Stavros Garantziotis
Publikováno v:
eLife, Vol 9 (2020)
Lung disease causes significant morbidity and mortality, and is exacerbated by environmental injury, for example through lipopolysaccharide (LPS) or ozone (O3). Toll-like receptors (TLRs) orchestrate immune responses to injury by recognizing pathogen
Externí odkaz:
https://doaj.org/article/e3dac700dd8e4f4eb86e206a0c3f77fa
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0193104 (2018)
Macrophages are specialized phagocytes that play an essential role in inflammation, immunity, and tissue repair. Profiling the global proteomic response of macrophages to microbial molecules such as bacterial lipopolysaccharide is key to understandin
Externí odkaz:
https://doaj.org/article/9e4090d26e5e4546a180b8b66c3e0522
Autor:
Jerry A Nick, Silvia M Caceres, Jennifer E Kret, Katie R Poch, Matthew Strand, Anna V Faino, David P Nichols, Milene T Saavedra, Jennifer L Taylor-Cousar, Mark W Geraci, Ellen L Burnham, Michael B Fessler, Benjamin T Suratt, Edward Abraham, Marc Moss, Kenneth C Malcolm
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162490 (2016)
Acute Respiratory Distress Syndrome (ARDS) severity may be influenced by heterogeneity of neutrophil activation. Interferon-stimulated genes (ISG) are a broad gene family induced by Type I interferons, often as a response to viral infections, which e
Externí odkaz:
https://doaj.org/article/7aa3f31964a74421b4a67b658b9dc008
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95021 (2014)
The Immunity-Related GTPases (IRG) are a family of large GTPases that mediate innate immune responses. Irgm1 is particularly critical for immunity to bacteria and protozoa, and for inflammatory homeostasis in the intestine. Although precise functions
Externí odkaz:
https://doaj.org/article/023cf6d8a518421c962bd9d7ea94a410
Autor:
Daniel Menendez, Maria Shatz, Kathleen Azzam, Stavros Garantziotis, Michael B Fessler, Michael A Resnick
Publikováno v:
PLoS Genetics, Vol 7, Iss 3, p e1001360 (2011)
In recent years the functions that the p53 tumor suppressor plays in human biology have been greatly extended beyond "guardian of the genome." Our studies of promoter response element sequences targeted by the p53 master regulatory transcription fact
Externí odkaz:
https://doaj.org/article/1c851161da124fd6ab494edb49d4b45a
Autor:
Neha A, Sathe, Eric D, Morrell, Pavan K, Bhatraju, Michael B, Fessler, Renee D, Stapleton, Mark M, Wurfel, Carmen, Mikacenic
Publikováno v:
Critical Care Medicine. 51:e13-e18
We sought to determine whether hyperinflammatory acute respiratory distress syndrome (ARDS) and hypoinflammatory ARDS, which have been associated with differences in plasma biomarkers and mortality risk, also display differences in bronchoalveolar la
Autor:
Florencia Pascual, Mert Icyuz, Peer Karmaus, Ashley Brooks, Elizabeth Van Gorder, Michael B. Fessler, Natalie D. Shaw
Publikováno v:
Scientific Reports. 13
Cranial neural crest cells (cNCC) are a multipotent embryonic cell population that give rise to a diverse set of cell types. These cells are particularly vulnerable to external metabolic stressors, as exemplified by the association between maternal h
Autor:
Jennifer H. Madenspacher, Eric D. Morrell, Jeffrey G. McDonald, Bonne M. Thompson, Yue Li, Konstantin G. Birukov, Anna A. Birukova, Renee D. Stapleton, Aidin Alejo, Peer W. Karmaus, Julie M. Meacham, Prashant Rai, Carmen Mikacenic, Mark M. Wurfel, Michael B. Fessler
Publikováno v:
JCI Insight. 8
Autor:
Michael A. Resnick, Michael B. Fessler, Stavros Garantziotis, Melissa A. Troester, Erin L. Kirk, Maria Shatz, Pierre R. Bushel, Daniel Menendez, Julie M. Lowe
PDF file - 249K, Figure S1. p53 activation by Nutlin-3 induces pro-inflammatory genes. Figure S2. NF-kB plays a role in gene regulation induced by Nutlin-3. Figure S3. Microarray analysis Nutlin-3 and LPS-treated macrophages identifies chemokine gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::572e21b214fef0ff96174ede4e57bbc4
https://doi.org/10.1158/0008-5472.22401287.v1
https://doi.org/10.1158/0008-5472.22401287.v1