Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Michael B, Lilly"'
Autor:
Michael B. Lilly, Chunli Wu, Yu Ke, Wen‐Pin Chen, Adam C. Soloff, Kent Armeson, Noriko N. Yokoyama, Xiaotian Li, Liankun Song, Ying Yuan, Christine E. McLaren, Xiaolin Zi
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 3, Pp n/a-n/a (2024)
Abstract Purpose Our preclinical studies showed that lycopene enhanced the anti‐prostate cancer efficacy of docetaxel in animal models. A phase I trial (NCT0149519) was conducted to identify an optimum dose of synthetic lycopene in combination with
Externí odkaz:
https://doaj.org/article/5c65eef1c6c54d5eaf06f95c1a59df0d
Autor:
Toros A. Dincman, Joseph A. Q. Karam, Antonio Giordano, Hong Li, Leylah M. Drusbosky, Theodore S. Gourdin, Philip H. Howe, Michael B. Lilly
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
PurposeAnalysis of circulating tumor DNA (ctDNA) in patients with metastatic prostate cancer (mPC) provides an opportunity to identify and monitor genomic alterations during a patient’s treatment course. We evaluated whether the presence of specifi
Externí odkaz:
https://doaj.org/article/6b361e927a574aefacb24a086c8a7f8e
Autor:
Bradley A. Krisanits, Pamela Woods, Lourdes M. Nogueira, Demarcus D. Woolfork, Courtney E. Lloyd, Andrew Baldwin, Callan C. Frye, Kendell D. Peterson, Sean D. Cosh, Qi-Jin Guo, Laura S. Spruill, Michael B. Lilly, Kristi Helke, Hong Li, George S. Hanna, Mark T. Hamann, Courtney Thomas, Mahtabuddin Ahmed, Monika B. Gooz, Victoria J. Findlay, David P. Turner
Publikováno v:
Translational Oncology, Vol 17, Iss , Pp 101350- (2022)
The molecular implications of food consumption on cancer etiology are poorly defined. The rate of nutrition associated non-enzymatic glycoxidation, a reaction that occurs between reactive carbonyl groups on linear sugars and nucleophilic amino, lysyl
Externí odkaz:
https://doaj.org/article/cec52ade50dc4295875eee77c2f2d05b
Autor:
Oluwole Adeyemi Babatunde, John L. Pearce, Melanie S. Jefferson, Lewis J. Frey, Peggi M. Angel, Richard R. Drake, Caitlin G. Allen, Michael B. Lilly, Stephen J. Savage, Chanita Hughes Halbert
Publikováno v:
Diseases, Vol 10, Iss 4, p 75 (2022)
Background: A better understanding of neighborhood-level factors’ contribution is needed in order to increase the precision of cancer control interventions that target geographic determinants of cancer health disparities. This study characterized t
Externí odkaz:
https://doaj.org/article/fae010c95d0a4165abccf296d1380f91
Autor:
Marcus Moses, MS, Alex Niu, MD, Michael B. Lilly, MD, Andrew W. Hahn, MD, Roberto Nussenzveig, PhD, Elisa Ledet, PhD, Charlotte Manogue, MPH, Patrick Cotogno, MSPH, Brian Lewis, MD, MPH, Jodi Layton, MD, Neeraj Agarwal, MD, Oliver Sartor, MD, Pedro C. Barata, MD, MSc
Publikováno v:
Cancer Treatment and Research Communications, Vol 24, Iss , Pp 100193- (2020)
Background: The crossover from abiraterone acetate (AA) to enzalutamide (ENZA) is a frequent approach in clinical practice. Our aim was to explore the role of genomic alterations as putative biomarkers of response to sequential AA followed by ENZA in
Externí odkaz:
https://doaj.org/article/91c96b47cba746c491c1996c235c077a
Supplementary Figures S1-S5.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5dbd95652f5e165fd0c4fbc837a9bc6
https://doi.org/10.1158/1541-7786.22519218
https://doi.org/10.1158/1541-7786.22519218
Autor:
Michael B. Lilly, Jonathan W. Neidigh, Ryan Bremer, Maryam Tabrizizad, Chao Zhang, Marina Zemskova, Sheldon Holder
The pim-1 kinase is a true oncogene that has been implicated in the development of leukemias, lymphomas, and prostate cancer, and is the target of drug development programs. We have used experimental approaches to identify a selective, cell-permeable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3549cfaa6fda859ec14c62f1cbc0296d
https://doi.org/10.1158/1535-7163.c.6532014.v1
https://doi.org/10.1158/1535-7163.c.6532014.v1
Autor:
Massimo Cristofanilli, Aditya Bardia, Richard B. Lanman, Stephen R. Fairclough, Victoria M. Raymond, Benjamin L. Maughan, Neeraj Agarwal, Benjamin B. Bridges, Barbara A. Parker, Adam M. Brufsky, Alice C. Fan, Benedito A. Carneiro, Sandip P. Patel, Mohammad Amin Nezami, Michael B. Lilly, Tracy Nance, Aaron Hardin, Jennifer Yen, Oliver Sartor, Thereasa A. Rich, Neelima Vidula
Purpose:PARP inhibitors (PARPi) are efficacious in multiple cancers harboring germline (and possibly somatic) BRCA1/2 mutations. Acquired reversions can restore BRCA1/2 function, causing resistance to PARPi and/or platinum-based chemotherapy. The opt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32427315b0f6dd8f14f80ddf82eba7e3
https://doi.org/10.1158/1078-0432.c.6529925.v1
https://doi.org/10.1158/1078-0432.c.6529925.v1
Autor:
Massimo Cristofanilli, Aditya Bardia, Richard B. Lanman, Stephen R. Fairclough, Victoria M. Raymond, Benjamin L. Maughan, Neeraj Agarwal, Benjamin B. Bridges, Barbara A. Parker, Adam M. Brufsky, Alice C. Fan, Benedito A. Carneiro, Sandip P. Patel, Mohammad Amin Nezami, Michael B. Lilly, Tracy Nance, Aaron Hardin, Jennifer Yen, Oliver Sartor, Thereasa A. Rich, Neelima Vidula
Supplemental Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213533586056e2ed5d7de6952a3e5aaf
https://doi.org/10.1158/1078-0432.22478339.v1
https://doi.org/10.1158/1078-0432.22478339.v1
Autor:
Michael B. Lilly, Jonathan W. Neidigh, Ryan Bremer, Maryam Tabrizizad, Chao Zhang, Marina Zemskova, Sheldon Holder
Supplementary Data from Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb40ea0bab3e5a1fda3d73d2ebd074b
https://doi.org/10.1158/1535-7163.22485591.v1
https://doi.org/10.1158/1535-7163.22485591.v1