Výsledky vyhledávání - "Michael Ausborn"

The protective effect of free and membrane-bound cryoprotectants during freezing and freeze-drying of liposomes

Autor: Helmut W. Meyer, Michael Ausborn, Heinz Fabian, Hans Schreier, Peter Nuhn, G. Brezesinski

Publikováno v: Journal of Controlled Release. 30:105-116

Liposomes were prepared from natural (EPC) and hydrogenated (HEPC) egg phosphatidylcholine, with and without cholesterol (CHOL), from sucrose fatty acid ester (SPS7; sucrose-palmitate/stearate) with CHOL and dicetylphosphate (DCP) or from EPC and HEP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5359b600094e40c7b6b84813e78aed97
https://doi.org/10.1016/0168-3659(94)90257-7

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Pulmonary delivery of amikacin liposomes and acute liposome toxicity in the sheep

Autor: Arlene A. Stecenko, David Soucy, Ricardo J. Gonzalez-Rothi, Kenneth J. McNicol, Michael Ausborn, Hans Schreier, Hartmut Derendorf

Publikováno v: International Journal of Pharmaceutics. 87:183-193

Although liposome-encapsulated antibiotics designed for intrapulmonary delivery by instillation or aerosolization have been proposed, little is known about the pharmacokinetic profile and toxicity of liposomal drug formulations when delivered to the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d01c76d76197bb21786c6a422720a296
https://doi.org/10.1016/0378-5173(92)90242-t

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Stability of Proteins Encapsulated in Injectable and Biodegradable Poly(lactide-co-glycolide)-Glucose Millicylinders

Autor: Oliver Lambert, Steven P. Schwendeman, Michael Ausborn, Jichao Kang

Purpose To characterize protein stability in poly(lactide-co-glycolide) 50/50-glucose star (PLGA-Glu) injectable millicylinders and to compare results with linear PLGA 50/50. Methods Bovine serum albumin (BSA), a model protein, was encapsulated in PL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a1fd204dabbc9fcc0bc68ce6207a031
https://europepmc.org/articles/PMC4269258/

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Poly(ethylene carbonate): a thermoelastic and biodegradable biomaterial for drug eluting stent coatings?

Autor: Ralf Wombacher, Phillip Hanefeld, Ullrich Westedt, Michael Ausborn, S. Zimmermann, Florian Unger, Thomas Kissel, Andreas Greiner

Publikováno v: Journal of controlled release : official journal of the Controlled Release Society. 117(3)

A first feasibility study exploring the utility of poly(ethylene carbonate) (PEC) as coating material for drug eluting stents under in vitro conditions is reported. PEC (Mw 242 kDa, Mw/Mn = 1.90) was found to be an amorphous polymer with thermoelasti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38392ff639de84d2b02be698bf45a407
https://pubmed.ncbi.nlm.nih.gov/17207879

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The preparation and characterization of lipid vesicles containing esters of sucrose and fatty acids

Autor: Dieter Arndt, Michael Ausborn, Helmut W. Meyer, Bendas Frank, Peter Nuhn, P. Schenk

Publikováno v: Journal of Microencapsulation. 6:95-103

Encapsulation and electron microscopy studies have shown that aqueous dispersions of several nonionic emulsifiers with sucrosepalmitatestearate (SPS) structure and cholesterol (Chol) result in synthetic lipid vesicles. This was demonstrated for the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94776cf8e80845e7b3ffb9eb6cd58b6e
https://doi.org/10.3109/02652048909019906

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