Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Michael Anthony Harris"'
Autor:
and Timothy C. Walsgrove, Clive J. Moores, Richard Neville Saunders, Jerome F. Hayes, Richard J. Atkins, Lynne P. Crawford, Michael Anthony Harris, Christopher Wicks, Gary F. Breen, Trevor J. Grinter, Andrew C. Share
Publikováno v:
Organic Process Research & Development. 1:185-197
The 3,4,8-trisubstituted quinoline derivatives 2-butyryl-8-methoxy-4-[(2-methylphenyl)amino]quinoline and 3-butyryl-8-(2-hydroxyethoxy)-4-[(2-methylphenyl)amino]quinoline were prepared using five novel synthetic strategies, each involving a different
Autor:
John Barry Harbridge, Nigel J. P. Broom, Graham Walker, Richard J. Atkins, Steven Coulton, Neal Frederick Osborne, Irene Stirling-François, Michael Anthony Harris
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :179-188
(5R)-(Z)-6-(1-Methyl-1,2,3-triazol-4-ylmethylene)penem-3-carboxylic acid 34(BRL 42715) has been prepared from 6-aminopenicillanic acid 4(6-APA) by a short, stereoselective and efficient route via the novel intermediate, p-methoxybenzyl (5R, 6S)-6-bro
Autor:
J. Sydney Davies, Michael Anthony Harris, David J. Merrikin, Richard Keith Anderson, Roger J. Ponsford, Trevor J. Grinter, Carol F. Smith, Christina A. Mitchell, Suzanne C. Cosham, Andrew V. Stachulski, Pauline C. A. Chapman
Publikováno v:
The Journal of Antibiotics. 46:331-342
Syntheses are described for penicillins (4b approximately 4i, 5a and 5b) which possess a 6 beta-(2-heteroaryl-3-substituted)-propenamido side-chain of fixed geometry. In vitro results for these compounds against a range of Gram-positive and Gram-nega
Autor:
Irene Stirling-François, Neal Frederick Osborne, Graham Walker, Richard J. Atkins, John Barry Harbridge, Michael Anthony Harris, Steven Coulton, Nigel J. P. Broom
Publikováno v:
ChemInform. 25
(5R)-(Z)-6-(1-Methyl-1,2,3-triazol-4-ylmethylene)penem-3-carboxylic acid 34(BRL 42715) has been prepared from 6-aminopenicillanic acid 4(6-APA) by a short, stereoselective and efficient route via the novel intermediate, p-methoxybenzyl (5R, 6S)-6-bro
Autor:
J. D. Hinks, Richard L. Elliot, Michael J. Pearson, Suzanne C. Cosham, A. John Eglington, John Lowther, John V. Syms, Pauline C. A. Chapman, Roger J. Ponsford, Michael Anthony Harris, David J. Merrikin, Pamela Brown, Stephen H. Calvert
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :881-891
A series of (Z)-2-alkyloxyimino-2-(2-aminothiazol-4-yl)acetamidopenicillins has been prepared. New methodology has been developed to prepare tertiary alkyl oximes. High stability to β-lactamases and potent antibacterial activity have been achieved a