Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Michael A. Suster"'
A Multichannel Miniaturized Dielectric Blood Coagulometer for Point-of-Care Assessment of Hemostasis
Publikováno v:
2022 IEEE Biomedical Circuits and Systems Conference (BioCAS).
Autor:
Pedram Mohseni, Yuncheng Man, Jane A. Little, Michael A. Suster, Umut A. Gurkan, Ran An, Debnath Maji, Sanjay P Ahuja
Publikováno v:
Lab Chip
Alterations in the deformability of red blood cells (RBCs), occurring in hemolytic blood disorders such as sickle cell disease (SCD), contribute to vaso-occlusion and disease pathophysiology. There are few functional in vitro assays for standardized
Autor:
Kara L. Bane, Evi X. Stavrou, Pedram Mohseni, Aman Opneja, Brigid Wilson, Debnath Maji, Michael A. Suster
Publikováno v:
Thromb Haemost
Background There are acute settings where assessing the anticoagulant effect of direct oral anticoagulants (DOACs) can be useful. Due to variability among routine coagulation tests, there is an unmet need for an assay that detects DOAC effects within
Autor:
Sina Pourang, Ujjal D.S. Sekhon, Dante Disharoon, Sanjay P. Ahuja, Michael A. Suster, Anirban Sen Gupta, Pedram Mohseni
Publikováno v:
Biosens Bioelectron
Rapid assessment of the fibrinolytic status in whole blood at the point-of-care/point-of-injury (POC/POI) is clinically important to guide timely management of uncontrolled bleeding in patients suffering from hyperfibrinolysis after a traumatic injur
Autor:
Sina Pourang, Michael A. Suster, Pedram Mohseni, Anirban Sen Gupta, Debnath Maji, Ujjal D. S. Sekhon
Publikováno v:
2020 IEEE SENSORS.
This paper reports on the use of a microfluidic dielectric sensor, termed ClotChip, for monitoring the fibrin polymerization effects on whole blood coagulation. The ClotChip sensor readout captures the temporal variation in the normalized real part o
Autor:
Debnath Maji, Erdem Kucukal, Michael A. Suster, Anirban Sen Gupta, Umut A. Gurkan, Evi X. Stavrou, Ujjal D. S. Sekhon, Pedram Mohseni
Publikováno v:
IEEE Transactions on Biomedical Circuits and Systems. 11:1459-1469
This paper describes the design, fabrication, and testing of a microfluidic sensor for dielectric spectroscopy (DS) of human whole blood during coagulation. The sensor, termed ClotChip, employs a three-dimensional (3D), parallel-plate, capacitive sen
Publikováno v:
Blood. 138:1882-1882
Background: There is an intimate link between inflammation and thrombosis, and patients with pro-inflammatory/infectious disorders develop a hypercoagulable state. Extant coagulation assays are unable to distinguish the pro-coagulant state of a patie
Publikováno v:
ISCAS
Dielectric spectroscopy (DS) is a powerful monitoring technique that can extract important molecular and cellular properties from a variety of biological materials. DS measurements on human whole blood can reveal a wealth of physiologic information,
Autor:
Anirban Sen Gupta, Debnath Maji, Ujjal D. S. Sekhon, Pedram Mohseni, Sina Pourang, Michael A. Suster
Publikováno v:
2019 IEEE SENSORS.
This paper reports on capturing the morphological changes in red blood cells (RBCs) during platelet-driven blood clot retraction using a microfluidic dielectric sensor, termed ClotChip. The sensor is based on the technique of dielectric spectroscopy
Autor:
Umut A. Gurkan, Ran An, Jane A. Little, Yuncheng Man, Pedram Mohseni, Michael A. Suster, Sanjay P Ahuja, Debnath Maji
Publikováno v:
Blood. 136:10-10
Introduction: Sickle cell disease (SCD) is a recessive genetic disorder caused by the mutated sickle hemoglobin (HbS) in red blood cells (RBCs). HbS polymerizes in a hypoxic environment, which leads to increased adhesiveness and decreased deformabili