Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Michael A. Satre"'
Autor:
Michael A. Satre, Heng Jiang, Douglas C. Harnish, D. M. Kochhar, Michael Gyda, Kenneth E. Ugen, Lan X. Chen, Dianne Robert Soprano, Kenneth J. Soprano
Publikováno v:
Mechanisms of Development. 45:243-253
We have previously shown that oral treatment of pregnant mice with all-trans retinoic acid (RA) at doses which cause 100% fetal dysmorphogenesis results in a rapid elevation in the mRNA of one specific isoform of the RA receptor-beta, RAR-beta 2, in
Publikováno v:
Biology of Reproduction. 46:802-810
Vitamin A and its analogs (retinoids) have acquired particular significance in embryonic development since the discovery that retinoic acid (RA) possesses properties of an endogenous morphogen and that embryonic tissues contain specific nuclear recep
Autor:
Vasantha Srikantan, Kesen Dang, Bin Wang, Alexis P. Godillot, Michael A. Satre, David B. Weiner, Kenneth E. Ugen, Felica Scales, William V. Williams
Publikováno v:
AIDS (London, England). 8(11)
OBJECTIVE To develop recombinant single-chain Fv fragments against HIV-1 gp120. METHODS A panel of human monoclonal antibody Fv fragments were generated against the HIV-1 gp120 by affinity selection from an antibody library expressed on the surface o
Publikováno v:
Toxicology and Applied Pharmacology. 96:429-441
Megadose supplements of vitamin A are under suspicion as hazards to the developing embryo after the discovery that two vitamin A-related drugs, Accutane and Tigason, are human teratogens. Retinoic acid (all-trans-RA) is a natural metabolite of vitami
Publikováno v:
Teratology. 39:341-348
Retinoic acid is a natural vitamin A derivative that undergoes oxidative metabolism in the body to yield several metabolites, which apparently represent the products of a detoxification pathway. To assess if such metabolic conversions diminished tera
Autor:
Michael A. Satre, D. M. Kochhar
Publikováno v:
Developmental biology. 133(2)
Retinoic acid, an endogenous metabolite of vitamin A (retinol), possesses striking biological activity akin to a morphogen in developing and regenerating vertebrate limbs. Systemic administration of retinoic acid (RA) to pregnant mammals during the p