Výsledky vyhledávání - "Michael A. Rogy"

Interleukin-10-deficient mice and inflammatory bowel disease associated cancer development

Autor: Sonja Kappel, Brigitte Tichy, Georg Oberhuber, Sanda Sturlan, Jacob E. Wang, Britta G. Beinhauer, Michael A. Rogy

Publikováno v: Carcinogenesis. 22:665-671

Interleukin-10-deficient mice develop colitis and colorectal cancer similar to the inflammatory bowel disease associated cancer in humans. The aim of this study was to identify possible mutations of oncogenes and tumour suppressor genes involved in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ced5b403fe2ff9d05509c4b2b2890b
https://doi.org/10.1093/carcin/22.4.665

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Combined radiochemotherapy of locally advanced unresectable pancreatic adenocarcinoma with mitomycin C plus 24-hour continuous infusional gemcitabine

Autor: Edgar Selzer, Michael A. Rogy, Annemarie Schratter, H. Ulrich-Pur, Gabriela Kornek, Richard Pötter, Gwendolyn Kraus, Werner Scheithauer

Publikováno v: International Journal of Radiation Oncology*Biology*Physics. 49:665-671

Background: In locally advanced pancreatic cancer, the combination of chemotherapy with radiotherapy is gaining increasing importance; although, in view of the reported long-term results of several contemporary trials, further improvements are certai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d57e2b8c869fb27fd23d07c04dde2f18
https://doi.org/10.1016/s0360-3016(00)01388-2

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Transfer of Interleukin-4 and Interleukin-10 in Patients with Severe Inflammatory Bowel Disease of the Rectum

Autor: Leaf Huang, Michael A. Rogy, Brigitte G. Beinhauer, Peter Pokieser, Walter Reinisch

Publikováno v: Human Gene Therapy. 11:1731-1741

Inflammatory bowel disease (IBD) comprises the two disorders ulcerative colitis (UC) and Crohn's disease (CD). Although the etiology is still unclear, initiation and aggravation of the inflammatory processes seem to be due to a massive local mucosal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9351982d74323cdf846b330f5621ce7
https://doi.org/10.1089/10430340050111386

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Endothelial cell adhesion molecule and PMNL response to inflammatory stimuli and AGE-modified fibronectin

Autor: Ilse Ferrara, Johannes Menzel, Michael A. Rogy, Sonja Skoupy, G. Sengoelge, Christa Zangerle, Walter H. Hörl, Gere Sunder-Plassmann, Manuela Födinger

Publikováno v: Kidney International. 54(5):1637-1651

Endothelial cell adhesion molecule and PMNL response to inflammatory stimuli and AGE-modified fibronectin. Background Atherosclerotic vascular disease is the leading cause of death in patients with diabetes mellitus and end-stage renal disease. Advan

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Gene transfer with IL-4 and IL-13 improves survival in lethal endotoxemia in the mouse and ameliorates peritoneal macrophages immune competence

Autor: Gregorio Aversa, Klaus Geissler, Brigitte G. Beinhauer, Udo Losert, Helge Brandmeier, Jacob E. Wang, Michael A. Rogy, Ramila Philip, Julie Baumhofer

Publikováno v: European Journal of Immunology. 28:610-615

Systemic anti-cytokine therapies have been unsuccessful in preventing mortality from gram-negative bacteremia in humans partly because of the failure to neutralize pro-inflammatory cytokines at sites of exaggerated production. In an attempt to delive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c7ace72b5e9512110cad935df7da6d21
https://doi.org/10.1002/(sici)1521-4141(199802)28:02<610::aid-immu610>3.0.co

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Gene therapy in surgery

Autor: Michael A. Rogy, P. Eisenburger, Britta Beinhauer, Ramila Philip, Julie M. Baumhofer, Helge Brandmeier, Udo Losert

Publikováno v: Acta Chirurgica Austriaca

With the increasing body of knowledge in molecular biology, gene transfer respectively gene therapy becomes more and more a valid therapeutic option.This is a critical review of gene therapy protocols for treatment of different types of cancer. Furth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4705c1d840f23a987e258b2443a82306
https://doi.org/10.1007/bf02620270

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Gene therapy in surgery

Autor: Ramila Philip, Udo Losert, Helge Brandmeier, Julie M. Baumhofer, Britta Beinhauer, P. Eisenburger, Michael A. Rogy

Publikováno v: European Surgery. 28:358-361

Background With the increasing body of knowledge in molecular biology, gene transfer respectively gene therapy becomes more and more a valid therapeutic option.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae2f2bab02046bc24c6da6e791747f62
https://doi.org/10.1007/bf02616288

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Interleukin 10 inhibits growth and granulocyte/macrophage colony-stimulating factor production in chronic myelomonocytic leukemia cells

Autor: Klaus Geissler, Michael A. Rogy, Sonja Skoupy, Leopold Öhler, Eva Kabrna, Barbara Bohle, Irene Virgolini, Klaus Lechner, Marietta Kollars, Manuela Födinger, M Leimer

Publikováno v: The Journal of Experimental Medicine

Autonomous release of hematopoietic growth factors may play a crucial role in the pathogenesis of certain hematological malignancies. Because of its cytokine synthesis-inhibiting action, interleukin 10 (IL-10) could be a potentially useful molecule t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2832b86fb69ea80ff88ed56c92e83efe
https://doi.org/10.1084/jem.184.4.1377

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Interleukin 1 binding to its type I, but not type II receptor, modulates the in vivo acute phase response

Autor: Hester S.A. Oldenburg, Jeffrey H. Pruitt, Douglas D. Lazarus, Michael A. Rogy, Richard Chizzonite, Stephen F. Lowry, Lyle L. Moldawer

Publikováno v: Cytokine. 7:510-516

Neutralizing monoclonal antibodies against the murine interleukin 1 (IL-1) type I (mAb 35F5) and type II receptor (mAb 4E2) were used to passively immunize mice prior to exogenous murine IL-1 alpha administration or a sterile-turpentine induced absce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8493e24f8725d5be33faf189d3c0348a
https://doi.org/10.1006/cyto.1995.0069

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A human tumor necrosis factor (TNF) alpha mutant that binds exclusively to the p55 TNF receptor produces toxicity in the baboon

Autor: W. J. Montegut, H Loetscher, Steven E. Calvano, C L Meschter, K C Hsu, K J Van Zee, Michael A. Rogy, M Chao, D Stüber, S A Stackpole

Publikováno v: The Journal of Experimental Medicine

A number of recent studies have demonstrated that cellular responses to tumor necrosis factor (TNF) mediated by the p55 and the p75 TNF receptors are distinct. To evaluate the relative in vivo toxicities of wild-type TNF alpha (wtTNF alpha) and a nov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830903160785aa2ebd85a97dc498caec
https://doi.org/10.1084/jem.179.4.1185

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