Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Michael A. Ports"'
Autor:
Michael O. Ports, Ruth A. Salmon, Blythe Sather, Heidi K. Jessup, Christopher R. Clouser, Lindsey Wimberly, Yue Jiang, Ronald J. Hause, David Kugler, Timothy G. Johnstone, Patrick Carlson, Wendy Curtis, Jon C. Jones, Alex Baturevych, Catherine Sierra, Collin Hauskins, Neha Soni, Melissa Works
Supplementary Figure 1 shows information about the differential effects of lenalidomide with additional scfvs and the selected scfv at an additional E:T ratio with OPM-2 and RPMI-8226 cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d0afc0464e3243fd418c73786778cf
https://doi.org/10.1158/1535-7163.22506366
https://doi.org/10.1158/1535-7163.22506366
Autor:
Michael O. Ports, Ruth A. Salmon, Blythe Sather, Heidi K. Jessup, Christopher R. Clouser, Lindsey Wimberly, Yue Jiang, Ronald J. Hause, David Kugler, Timothy G. Johnstone, Patrick Carlson, Wendy Curtis, Jon C. Jones, Alex Baturevych, Catherine Sierra, Collin Hauskins, Neha Soni, Melissa Works
Anti–B-cell maturation antigen (BCMA) chimeric antigen receptor (CAR) T cells have shown promising clinical responses in patients with relapsed/refractory multiple myeloma. Lenalidomide, an immunomodulatory drug, potentiates T cell functionality, d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec1de428704b5d6bdfb9b182aec9e142
https://doi.org/10.1158/1535-7163.c.6538380.v1
https://doi.org/10.1158/1535-7163.c.6538380.v1
Autor:
Michael O. Ports, Ruth A. Salmon, Blythe Sather, Heidi K. Jessup, Christopher R. Clouser, Lindsey Wimberly, Yue Jiang, Ronald J. Hause, David Kugler, Timothy G. Johnstone, Patrick Carlson, Wendy Curtis, Jon C. Jones, Alex Baturevych, Catherine Sierra, Collin Hauskins, Neha Soni, Melissa Works
anti-BCMA CAR T amino acid sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b406a8728513acff0fe733a8adcb7e7
https://doi.org/10.1158/1535-7163.22506351.v1
https://doi.org/10.1158/1535-7163.22506351.v1
Autor:
Michael O. Ports, Ruth A. Salmon, Blythe Sather, Heidi K. Jessup, Christopher R. Clouser, Lindsey Wimberly, Yue Jiang, Ronald J. Hause, David Kugler, Timothy G. Johnstone, Patrick Carlson, Wendy Curtis, Jon C. Jones, Alex Baturevych, Catherine Sierra, Collin Hauskins, Neha Soni, Melissa Works
Supplementary Figure 4 shows the effects of lenalidomide on CD27, CCR7, CD45RA, and CAR positivity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1925681cdee8d90e38f67e48891705e4
https://doi.org/10.1158/1535-7163.22506357.v1
https://doi.org/10.1158/1535-7163.22506357.v1
Autor:
Michael O. Ports, Ruth A. Salmon, Blythe Sather, Heidi K. Jessup, Christopher R. Clouser, Lindsey Wimberly, Yue Jiang, Ronald J. Hause, David Kugler, Timothy G. Johnstone, Patrick Carlson, Wendy Curtis, Jon C. Jones, Alex Baturevych, Catherine Sierra, Collin Hauskins, Neha Soni, Melissa Works
Supplementary Figure 2 shows the effect of lenalidomide on BCMA expression of the cell lines used in the experiments in this manuscript.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c42d08c0f6db0e0ef235edfd100324
https://doi.org/10.1158/1535-7163.22506363.v1
https://doi.org/10.1158/1535-7163.22506363.v1
Autor:
Michael O. Ports, Ruth A. Salmon, Blythe Sather, Heidi K. Jessup, Christopher R. Clouser, Lindsey Wimberly, Yue Jiang, Ronald J. Hause, David Kugler, Timothy G. Johnstone, Patrick Carlson, Wendy Curtis, Jon C. Jones, Alex Baturevych, Catherine Sierra, Collin Hauskins, Neha Soni, Melissa Works
Supplementary Figure 3 shows the effect of lenalidomide on cytokine production by anti-BCMA CAR T cells stimulated with BCMA beads for 24 hours.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e7b4172afe6d412aa4e8eaacba36b43
https://doi.org/10.1158/1535-7163.22506360.v1
https://doi.org/10.1158/1535-7163.22506360.v1
Autor:
Michael O. Ports, Ruth A. Salmon, Blythe Sather, Heidi K. Jessup, Christopher R. Clouser, Lindsey Wimberly, Yue Jiang, Ronald J. Hause, David Kugler, Timothy G. Johnstone, Patrick Carlson, Wendy Curtis, Jon C. Jones, Alex Baturevych, Catherine Sierra, Collin Hauskins, Neha Soni, Melissa Works
Supplementary Methods and Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ed1b249766c63e611f54d59f8c8051
https://doi.org/10.1158/1535-7163.22506354.v1
https://doi.org/10.1158/1535-7163.22506354.v1
Discovery of Potent and Selective MTH1 Inhibitors for Oncology: Enabling Rapid Target (In)Validation
Autor:
Julie Farand, Jeffrey E. Kropf, Peter Blomgren, Jianjun Xu, Aaron C. Schmitt, Zachary E. Newby, Ting Wang, Eisuke Murakami, Ona Barauskas, Jawahar Sudhamsu, Joy Y. Feng, Anita Niedziela-Majka, Brian E. Schultz, Karen Schwartz, Serge Viatchenko-Karpinski, Dmytro Kornyeyev, Adam Kashishian, Peidong Fan, Xiaowu Chen, Eric B. Lansdon, Michael O. Ports, Kevin S. Currie, William J. Watkins, Gregory T. Notte
Publikováno v:
ACS Med Chem Lett
[Image: see text] We describe the discovery of three structurally differentiated potent and selective MTH1 inhibitors and their subsequent use to investigate MTH1 as an oncology target, culminating in target (in)validation. Tetrahydronaphthyridine 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a8664fe5cf60201d9c5d872c2fbdf25
https://europepmc.org/articles/PMC7074220/
https://europepmc.org/articles/PMC7074220/
Autor:
Jeffrey B. Bradley, Michael A. Ports
Publikováno v:
World Environmental and Water Resources Congress 2019.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e5d20c33a551eb568ddd890266d4e36
https://doi.org/10.1061/9780784482377.010
https://doi.org/10.1061/9780784482377.010
Autor:
Michael A. Ports
Written by Michael A. Ports, this four-page laminated Genealogy at a Glance guide provides the information you'll need to begin and proceed successfully with your Tennessee research. Included in this guide are critical details about the key record so