Zobrazeno 1 - 10
of 407
pro vyhledávání: '"Michael A. McGrath"'
Autor:
George A. McCanney, Susan L. Lindsay, Michael A. McGrath, Hugh J. Willison, Claire Moss, Charles Bavington, Susan C. Barnett
Publikováno v:
Biology, Vol 8, Iss 3, p 52 (2019)
In vitro cell-based assays have been fundamental in modern drug discovery and have led to the identification of novel therapeutics. We have developed complex mixed central nervous system (CNS) cultures, which recapitulate the normal process of myelin
Externí odkaz:
https://doaj.org/article/5e502c83ef2e49248883baa9584230f4
Autor:
Larissa L.S. Scholte, Justin Browne, David J. Nolan, Peyton St. John, Katherine Tracy, Rafaela S. Thur, Ghangzhao Li, Susanna L. Lamers, Paige Bracci, Michael S. McGrath, Jeffrey M. Bethony
Publikováno v:
STAR Protocols, Vol 5, Iss 4, Pp 103365- (2024)
Summary: Kaposi sarcoma (KS) punch biopsies present unique challenges for extracting nucleic acids, which can be exacerbated by their long-term stabilization in RNAlater. Here, we present a protocol for simultaneously isolating DNA, RNA, and miRNA fr
Externí odkaz:
https://doaj.org/article/012808af16b4461dbb35af7448f38fdd
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2362 (2024)
Background/objective: Amyotrophic lateral sclerosis (ALS) is a diagnosis that incorporates a heterogeneous set of neurodegenerative processes into a single progressive and uniformly fatal disease making the development of a uniformly applicable thera
Externí odkaz:
https://doaj.org/article/d42e9120670f43a3aa48168a2fa01089
Autor:
Michael K. McGrath, Ali Abolhassani, Luke Guy, Ahmed M. Elshazly, John T. Barrett, Nahid F. Mivechi, David A. Gewirtz, Patricia V. Schoenlein
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Estrogen receptor positive (ER+) breast cancer is the most common breast cancer diagnosed annually in the US with endocrine-based therapy as standard-of-care for this breast cancer subtype. Endocrine therapy includes treatment with antiestrogens, suc
Externí odkaz:
https://doaj.org/article/3cca55924e8440b18214f9cbedfcc9fd
Autor:
Samuel J. Edens, Michael J. McGrath, Siyu Guo, Zijuan Du, Hemin Zhou, Lingshan Zhong, Zuhao Shi, Jieshuo Wan, Thomas D. Bennett, Ang Qiao, Haizheng Tao, Neng Li, Matthew G. Cowan
Publikováno v:
Advanced Science, Vol 10, Iss 8, Pp n/a-n/a (2023)
Abstract The last 20 years have seen many publications investigating porous solids for gas adsorption and separation. The abundance of adsorbent materials (this work identifies 1608 materials for CO2/N2 separation alone) provides a challenge to obtai
Externí odkaz:
https://doaj.org/article/5101db18f3fd462da5f10942612a39bf
Publikováno v:
Cells, Vol 12, Iss 7, p 1031 (2023)
Amyotrophic lateral sclerosis (ALS) is a clinical diagnosis used to define a neurodegenerative process that involves progressive loss of voluntary muscle function and leads to death within 2–5 years after diagnosis, in most cases because of respira
Externí odkaz:
https://doaj.org/article/84e2ee8b77b943fbbd627f70088db07b
Autor:
David J. Nolan, Rebecca Rose, Rongzhen Zhang, Alan Leong, Gary B. Fogel, Larissa L. S. Scholte, Jeffrey M. Bethony, Paige Bracci, Susanna L. Lamers, Michael S. McGrath
Publikováno v:
Viruses, Vol 14, Iss 12, p 2774 (2022)
Epidemic Kaposi’s sarcoma (KS), defined by co-infection with Human Herpes Virus 8 (HHV-8) and the Human Immunodeficiency Virus (HIV), is a major cause of mortality in sub-Saharan Africa. Antiretroviral therapy (ART) significantly reduces the risk o
Externí odkaz:
https://doaj.org/article/abcd94a85b304537988a321b24891cc2
Publikováno v:
Biomedicines, Vol 10, Iss 11, p 2907 (2022)
Amyotrophic lateral sclerosis (ALS) is a heterogeneous, progressive, and universally fatal neurodegenerative disease. A subset of ALS patients has measurable plasma levels of lipopolysaccharide (LPS) and C-reactive protein (CRP) consistent with low-g
Externí odkaz:
https://doaj.org/article/30722db4787c4e8c8b9fb21165019488
Autor:
Lee Wisner, Alanna Maguire, Katie R. Zellner, Colleen Ramsower, Lisa M. Rimsza, Michael S. McGrath, Betty Glinsmann-Gibson, Brandon T. Larsen
Publikováno v:
Biopreservation and Biobanking. 20:473-484
Background: Formalin-fixed, paraffin-embedded (FFPE) tissues are a valuable resource for clinical and basic science research. Paraffin blocks and the resulting unstained sections (USS) are often st...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b86cb2edd741625b9a8602b09605526
https://doi.org/10.1089/bio.2021.0023
https://doi.org/10.1089/bio.2021.0023
Autor:
Robert G. Miller, Rongzhen Zhang, Paige M. Bracci, Ari Azhir, Richard Barohn, Richard Bedlack, Michael Benatar, James D. Berry, Merit Cudkowicz, Edward J. Kasarskis, Hiroshi Mitsumoto, Georgios Manousakis, David Walk, Bjorn Oskarsson, Jeremy Shefner, Michael S. McGrath
Publikováno v:
Muscle & Nerve. 66:39-49
ALS is a heterogeneous disease that may be complicated or in part driven by inflammation. NP001, a regulator of macrophage activation, was associated with slowing disease progression in those with higher levels of the plasma inflammatory marker C-rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a331ea922bb51bd6b5ef53118452ab5
https://doi.org/10.1002/mus.27511
https://doi.org/10.1002/mus.27511