Zobrazeno 1 - 10
of 263
pro vyhledávání: '"Michael A. Mancini"'
Autor:
Michael J. Bolt, Jessica Oceguera, Pankaj K. Singh, Kazem Safari, Derek H. Abbott, Kaley A. Neugebauer, Maureen G. Mancini, Daniel A. Gorelick, Fabio Stossi, Michael A. Mancini
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109275- (2024)
Summary: The initial step in estrogen-regulated transcription is the binding of a ligand to its cognate receptors, named estrogen receptors (ERα and ERβ). Phytochemicals present in foods and environment can compete with endogenous hormones to alter
Externí odkaz:
https://doaj.org/article/f27ba319ca7e4cc1b5641920f2a19da6
Autor:
Derek A. Abbott, Maureen G. Mancini, Michael J. Bolt, Adam T. Szafran, Kaley A. Neugebauer, Fabio Stossi, Daniel A. Gorelick, Michael A. Mancini
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e23119- (2024)
In this study we present an inducible biosensor model for the Estrogen Receptor Beta (ERβ), GFP-ERβ:PRL-HeLa, a single-cell-based high throughput (HT) in vitro assay that allows direct visualization and measurement of GFP-tagged ERβ binding to ER-
Externí odkaz:
https://doaj.org/article/72f160106c83423bac993c7ba9428a4b
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105200- (2022)
Summary: The United States Environmental Protection Agency (EPA) has been pursuing new high throughput in vitro assays to characterize endocrine disrupting chemicals (EDCs) that interact with estrogen receptor signaling. We characterize two new PRL-H
Externí odkaz:
https://doaj.org/article/9e5eeb02d01246dca186bc7f6ecadcb7
Autor:
Pratim Chowdhury, Dimuthu Perera, Reid T. Powell, Tia Talley, Durga Nand Tripathi, Yong Sung Park, Michael A. Mancini, Peter Davies, Clifford Stephan, Cristian Corfa, Ruhee Dere
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Loss of primary cilia in cells deficient for the tumor suppressor von Hippel Lindau (VHL) arise from elevated Aurora Kinase A (AURKA) levels. VHL in its role as an E3 ubiquitin ligase targets AURKA for degradation and in the absence of VHL,
Externí odkaz:
https://doaj.org/article/2ca73e95c5024ae6a9c8ae5e0e85611a
Autor:
Anubama Rajan, Ashley Morgan Weaver, Gina Marie Aloisio, Joseph Jelinski, Hannah L. Johnson, Susan F. Venable, Trevor McBride, Letisha Aideyan, Felipe-Andrés Piedra, Xunyan Ye, Ernestina Melicoff-Portillo, Malli Rama Kanthi Yerramilli, Xi-Lei Zeng, Michael A. Mancini, Fabio Stossi, Anthony W. Maresso, Shalaka A. Kotkar, Mary K. Estes, Sarah Blutt, Vasanthi Avadhanula, Pedro A. Piedra
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT There is an unmet need for preclinical models to understand the pathogenesis of human respiratory viruses and predict responsiveness to immunotherapies. Airway organoids can serve as an ex vivo human airway model to study respiratory viral p
Externí odkaz:
https://doaj.org/article/d19e06d3907d4ae0a97b769078363018
Autor:
Michael J. Bolt, Pankaj Singh, Caroline E. Obkirchner, Reid T. Powell, Maureen G. Mancini, Adam T. Szafran, Fabio Stossi, Michael A. Mancini
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103227- (2021)
Summary: Transcription is a highly regulated sequence of stochastic processes utilizing many regulators, including nuclear receptors (NR) that respond to stimuli. Endocrine disrupting chemicals (EDCs) in the environment can compete with natural ligan
Externí odkaz:
https://doaj.org/article/45c83f8c8620468ca475b94663c889a3
Autor:
Pratim Chowdhury, Dimuthu Perera, Reid T. Powell, Tia Talley, Durga Nand Tripathi, Yong Sung Park, Michael A. Mancini, Peter Davies, Clifford Stephan, Cristian Coarfa, Ruhee Dere
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/49a5d424e3764f0984f00087f520a0bd
Autor:
Hai Wang, Lin Tian, Amit Goldstein, Jun Liu, Hin-Ching Lo, Kuanwei Sheng, Thomas Welte, Stephen T.C. Wong, Zbigniew Gugala, Fabio Stossi, Chenghang Zong, Zonghai Li, Michael A. Mancini, Xiang H.-F. Zhang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
The bone microenvironment may alter therapeutic responses of disseminated breast cancer cells. Here the authors establish anex vivobone metastasis model, termed BICA, to delineate the effects of bone microenvironment and to rapidly discover anti-meta
Externí odkaz:
https://doaj.org/article/277b6262d22942908dfbeb83711138c3
Autor:
Benjamin C. Hawthorne, Matthew E. Shuman, Ian J. Wellington, Michael R. Mancini, Cory R. Hewitt, Caitlin G. Dorsey, Julio O. Quintana, Michael Talamo, Elifho Obopilwe, Mark P. Cote, Augustus D. Mazzocca, Paul M. Sethi
Publikováno v:
Journal of Shoulder and Elbow Surgery. 32:326-332
Subscapularis failure is a troublesome complication following anatomic total shoulder arthroplasty (aTSA). Commonly discarded during aTSA, the long head of the biceps tendon (LHBT) may offer an efficient and cheap autograft for the augmentation of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e232c05c4c5736256ea9548cba7d0b
https://doi.org/10.1016/j.jse.2022.07.021
https://doi.org/10.1016/j.jse.2022.07.021
Publikováno v:
Clinics in Sports Medicine. 42:81-94
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e14700f47c0e4731ff28e3e79947a566
https://doi.org/10.1016/j.csm.2022.08.004
https://doi.org/10.1016/j.csm.2022.08.004