Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Michael A. Kemp"'
Autor:
William Cvammen, Michael G. Kemp
Publikováno v:
JID Innovations, Vol 4, Iss 6, Pp 100308- (2024)
Many aspects of skin biochemistry and physiology are known to vary over the course of the 24-hour day. Traditional approaches to study circadian rhythms in the skin have employed rodents or human subjects, which limit the experimental variables that
Externí odkaz:
https://doaj.org/article/24a30add3df44ca492955791f80c0f72
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102838- (2024)
Summary: UV radiation induces the formation of adducts in genomic DNA within cells that are later found to be present in cell-free fractions associated with extracellular vesicles (EVs) outside of cells. Here, we present a protocol for isolating UV p
Externí odkaz:
https://doaj.org/article/3d742588874d4152aaf02100ace7ef32
Autor:
Mariam Maksutova, BS, Michael T. Kemp, MD, Julie Evans, BA, Sriganesh B. Sharma, MD, PhD, Christian Vercler, MD, Gurjit Sandhu, PhD
Publikováno v:
Annals of Surgery Open, Vol 4, Iss 2, p e276 (2023)
Externí odkaz:
https://doaj.org/article/fdce7dbb350b4e98833ee6556bd74e8d
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Nucleotide excision repair (NER) and cell cycle checkpoints impact the ability of the anti-cancer drug cisplatin to inhibit cell proliferation and induce cell death. Genetic studies have shown that both NER and cell cycle progression are imp
Externí odkaz:
https://doaj.org/article/f2b3929afad44538b799891a484445ab
Autor:
Timothy C. Frommeyer, Craig A. Rohan, Dan F. Spandau, Michael G. Kemp, Molly A. Wanner, Elizabeth Tanzi, Jeffrey B. Travers
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
The occurrence of non-melanoma skin cancer (NMSC) is closely linked with advanced age and ultraviolet-B (UVB) exposure. More specifically, the development of NMSC is linked to diminished insulin-like growth factor-1 (IGF-1) signaling from senescent d
Externí odkaz:
https://doaj.org/article/436a0690d7574f35aa2dd2fc5a7f6e5b
Autor:
Ben E Biesterveld, Aaron M Williams, Hasan B Alam, Michael T Kemp, Glenn K Wakam, Luke Pumiglia
Publikováno v:
Trauma Surgery & Acute Care Open, Vol 6, Iss 1 (2021)
Background Traumatic brain injury (TBI) is a leading cause of morbidity and mortality. There are currently no cytoprotective treatments for TBI. There is growing evidence that the histone deacetylase inhibitor valproic acid (VPA) may be beneficial in
Externí odkaz:
https://doaj.org/article/fc6bd6b9dbfe4dd3a36833f15562aadf
Autor:
Ben E Biesterveld, Umar F Bhatti, Aaron M Williams, Yongqing Li, Hasan B Alam, Michael T Kemp, Rachel L O'Connell, Glenn K Wakam, Ali Siddiqui, Nathan Graham, Kiril Chtraklin, Alizeh Shamshad
Publikováno v:
Trauma Surgery & Acute Care Open, Vol 6, Iss 1 (2021)
Background Trauma and sepsis are individually two of the leading causes of death worldwide. When combined, the mortality is greater than 50%. Thus, it is imperative to have a reproducible and reliable animal model to study the effects of polytrauma a
Externí odkaz:
https://doaj.org/article/5bdfe70f8fc2480882ba381daa239443
Publikováno v:
JID Innovations, Vol 1, Iss 3, Pp 100023- (2021)
Spironolactone (SP) is used to treat a variety of disparate disease states ranging from heart failure to acne through antagonism of the mineralocorticoid and androgen receptors. Although normally taken as an oral medication, recent studies have explo
Externí odkaz:
https://doaj.org/article/f55855ea416b4f0fb5773e0a2674822d
Autor:
Kevin N. Harrell, Arthur D. Grimes, Harkanwar Gill, Jessica K. Reynolds, Walker R. Ueland, Jason D. Sciarretta, Samual R. Todd, Marc D. Trust, Marielle Ngoue, Bradley W. Thomas, Sullivan A. Ayuso, Aimee LaRiccia, M Chance Spalding, Michael J. Collins, Bryan R. Collier, Basil S. Karam, Marc A. de Moya, Mark J. Lieser, John M. Chipko, James M. Haan, Kelly L. Lightwine, Daniel C. Cullinane, Carolyne R. Falank, Ryan C. Phillips, Michael T. Kemp, Hasan B. Alam, Pascal O. Udekwu, Gloria D. Sanin, Amy N. Hildreth, Walter L. Biffl, Kathryn B. Schaffer, Gary Marshall, Omaer Muttalib, Jeffry Nahmias, Niti Shahi, Steven L. Moulton, Robert A. Maxwell
Publikováno v:
The American Journal of Surgery. 225:1069-1073
Few studies have investigated risk factors for recurrence of blunt traumatic abdominal wall hernias (TAWH).Twenty trauma centers identified repaired TAWH from January 2012 to December 2018. Logistic regression was used to investigate risk factors for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d7a405155f8f1cfa8907aeff6dcd3d
https://doi.org/10.1016/j.amjsurg.2022.12.006
https://doi.org/10.1016/j.amjsurg.2022.12.006
Publikováno v:
Trauma Surgery & Acute Care Open, Vol 5, Iss 1 (2020)
Prior to the covid-19 pandemic, telehealth was already being rapidly adopted nationally by healthcare systems. During the covid-19 pandemic, increased use of telehealth may be considered as a risk reduction strategy. Benefits of this strategy may be
Externí odkaz:
https://doaj.org/article/1a55565eeb5e4d02b1bbe6a17e822e90