Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Michael A. Kayser"'
Autor:
Wendy J. Introne, Michael A. Kayser, William A. Gahl, Hwaida Hannoush, Sook-Jin Lee, Vandana Sachdev, Kevin O'Brien, Marcus Y. Chen, Pim Suwannarat
Publikováno v:
Molecular Genetics and Metabolism. 105:198-202
Alkaptonuria is a rare metabolic disorder of tyrosine catabolism in which homogentisic acid (HGA) accumulates and is deposited throughout the spine, large joints, cardiovascular system, and various tissues throughout the body. In the cardiovascular s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::167c407d8c43da6e2df21a6c94315173
https://doi.org/10.1016/j.ymgme.2011.10.017
https://doi.org/10.1016/j.ymgme.2011.10.017
Autor:
Pim Suwannarat, Wendy J. Introne, Kevin O’Brien, Isa Bernardini, Thierry Vilboux, Roxanne Fischer, William A. Gahl, Marjan Huizing, Michael A. Kayser, Robert Kleta
Publikováno v:
Human Mutation. 30:1611-1619
Alkaptonuria (AKU) is a rare autosomal recessive metabolic disorder, characterized by accumulation of homogentisic acid, leading to darkened urine, pigmentation of connective tissue (ochronosis), joint an spine arthritis, and destruction of cardiac v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::876c8a84d9becf819ce856460594d910
https://doi.org/10.1002/humu.21120
https://doi.org/10.1002/humu.21120
Autor:
Hazel R. C. Screen, Vivek H. Chhaya, Dan L. Bader, Julia C. Shelton, Michael V. Kayser, David A. Lee
Publikováno v:
Annals of Biomedical Engineering. 33:1090-1099
Tendon is composed of type I collagen fibers, interspersed with proteoglycan matrix and cells. Glycosaminoglycans may play a role in maintaining the structural integrity of tendon, preventing excessive shearing between collagen components. This study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a9ae36db9ba3055adc5cbed2566ca5
https://doi.org/10.1007/s10439-005-5777-9
https://doi.org/10.1007/s10439-005-5777-9
Publikováno v:
Osteoarthritis and Cartilage. 12(1):17-24
Objective: This study examined the morphology of chondrocytes in articular cartilage from osteoarthritic (OA) and non-OA human femoral heads and in particular the appearance of a sub-population of cells with multiple elongated processes radiating up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::250213be7e6c366e8b718b81dc6e9e0e
Publikováno v:
Tissue Engineering. 8:453-467
HAPEX (hydroxyapatite-reinforced polyethylene composite) is a second-generation orthopedic biomaterial designed as a bone analog material, which has found clinical success. The use of topography in cell engineering has been shown to affect cell attac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea344c56e67c5c28a9597e66e3d0117a
https://doi.org/10.1089/107632702760184718
https://doi.org/10.1089/107632702760184718
Autor:
Isa Bernardini, Elizabeth Moylan, Vandana Sachdev, Ekaterini Tsilou, Kevin O’Brien, Monique B. Perry, Wendy J. Introne, Pim Suwannarat, Michael A. Kayser, Joy Bryant, James C. Reynolds, James Troendle, William A. Gahl
Alkaptonuria is a rare, autosomal recessive disorder of tyrosine degradation due to deficiency of the third enzyme in the catabolic pathway. As a result, homogentisic acid (HGA) accumulates and is excreted in gram quantities in the urine, which turns
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff6cd64e8047307b773ebaec07bf8cc
https://europepmc.org/articles/PMC3148330/
https://europepmc.org/articles/PMC3148330/
Autor:
Michael A. Kayser
Publikováno v:
Seminars in pediatric neurology. 15(3)
In the past few years, there has been a veritable explosion in the discovery of "new" inborn errors of metabolism. These new conditions are involved in complex pathways of intermediary metabolism affecting processes heretofore unknown. The phenotypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bee3e094a27471efabf3b4b2dc18419
https://pubmed.ncbi.nlm.nih.gov/18708003
https://pubmed.ncbi.nlm.nih.gov/18708003
Chondrocyte deformation within compressed agarose constructs at the cellular and sub-cellular levels
Autor:
David A. Lee, Martin M. Knight, Dan L. Bader, Bernadine Idowu, John F. Bolton, Michael V. Kayser
Publikováno v:
Journal of biomechanics. 33(1)
Mechanotransduction events in articular cartilage may be resolved into extracellular components followed by intracellular signalling events, which finally lead to altered cell response. Cell deformation is one of the former components, which has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::464cc7de2cc61c40ff947927f5eaad75
https://pubmed.ncbi.nlm.nih.gov/10609521
https://pubmed.ncbi.nlm.nih.gov/10609521