Zobrazeno 1 - 10
of 470
pro vyhledávání: '"Michael A. Jarvis"'
Autor:
Zujie Yan, Ruyi Pan, Junjie Zhang, Jianhe Sun, Xiaochun Ma, Nihua Dong, Xiaohui Yao, Jianchao Wei, Ke Liu, Yafeng Qiu, Katie Sealey, Hester Nichols, Michael A. Jarvis, Mathew Upton, Xiangdong Li, Zhiyong Ma, Juxiang Liu, Beibei Li
Publikováno v:
Vaccines, Vol 12, Iss 5, p 544 (2024)
Background: Streptococcus suis (S. suis) is a Gram-positive bacterium that causes substantial disease in pigs. S. suis is also an emerging zoonoses in humans, primarily in Asia, through the consumption of undercooked pork and the handling of infected
Externí odkaz:
https://doaj.org/article/d30ee04d4b65488982ebc446256f1a5d
Autor:
Rory C. F. de Brito, Kerry Holtham, Jessica Roser, Jack E. Saunders, Yvonne Wezel, Summer Henderson, Thekla Mauch, Beatriz Sanz-Bernardo, Jean-Pierre Frossard, Matthieu Bernard, Fabian Z. X. Lean, Alejandro Nunez, Simon Gubbins, Nicolás M. Suárez, Andrew J. Davison, Michael J. Francis, Michael Huether, Hafid Benchaoui, Jeremy Salt, Veronica L. Fowler, Michael A. Jarvis, Simon P. Graham
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Porcine reproductive and respiratory syndrome virus (PRRSV) remains a leading cause of economic loss in pig farming worldwide. Existing commercial vaccines, all based on modified live or inactivated PRRSV, fail to provide effective immunity against t
Externí odkaz:
https://doaj.org/article/ce0adbc03153451681f6323c4d708d43
Autor:
Kyle Rosenke, Matt C. Lewis, Friederike Feldmann, Eric Bohrnsen, Benjamin Schwarz, Atsushi Okumura, W. Forrest Bohler, Julie Callison, Carl Shaia, Catharine M. Bosio, Jamie Lovaglio, Greg Saturday, Michael A. Jarvis, Heinz Feldmann
Publikováno v:
JCI Insight, Vol 8, Iss 4 (2023)
The periodic emergence of SARS-CoV-2 variants of concern (VOCs) with unpredictable clinical severity and ability to escape preexisting immunity emphasizes the continued need for antiviral interventions. Two small molecule inhibitors, molnupiravir (MK
Externí odkaz:
https://doaj.org/article/8c4c6d11714643ca966ef175993be046
Autor:
Nihua Dong, Hester Nichols, Qing Sun, Xiaojun Chen, Jiayang Zheng, Zhixin Guan, Hailong Zhang, Andrew Davison, Yvonne Wezel, Zongjie Li, Beibei Li, Ke Liu, Donghua Shao, Yafeng Qiu, Jianhe Sun, Xiangdong Li, Mathew Upton, Zhiyong Ma, Michael A. Jarvis, Jianchao Wei
Publikováno v:
Vaccines, Vol 11, Iss 5, p 1004 (2023)
Streptococcus suis (S. suis) is a bacterial pathogen of pigs that has a major animal health and economic impact on the pig industry. Bovine herpesvirus-4 (BoHV-4) is a new virus-based vaccine vector that has been used for the immunogenic delivery of
Externí odkaz:
https://doaj.org/article/76f95f9e5be94e61a9d2633bdfc83f22
Autor:
Kyle Rosenke, Atsushi Okumura, Matthew C. Lewis, Friederike Feldmann, Kimberly Meade-White, W. Forrest Bohler, Amanda Griffin, Rebecca Rosenke, Carl Shaia, Michael A. Jarvis, Heinz Feldmann
Publikováno v:
JCI Insight, Vol 7, Iss 13 (2022)
The recent emergence of the SARS-CoV-2 Omicron variant of concern (VOC), which contains a heavily mutated spike protein capable of escaping preexisting immunity, identifies a continued need for interventional measures. Molnupiravir (MK-4482), an oral
Externí odkaz:
https://doaj.org/article/f79bebb8c067469d87b3b0e305f5ae71
Autor:
Maša Mavri, Valentina Kubale, Daniel P. Depledge, Jianmin Zuo, Christene A. Huang, Judith Breuer, Milka Vrecl, Michael A. Jarvis, Eva Jarc Jovičić, Toni Petan, Bernhard Ehlers, Mette M. Rosenkilde, Katja Spiess
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Infection of immunosuppressed transplant patients with the human γ-herpesvirus Epstein-Barr virus (EBV) is associated with post-transplant lymphoproliferative disease (PTLD), an often fatal complication. Immunosuppressed miniature pigs infected with
Externí odkaz:
https://doaj.org/article/ace78cd12fd74e3a972002de4a538673
Autor:
Kyle Rosenke, Frederick Hansen, Benjamin Schwarz, Friederike Feldmann, Elaine Haddock, Rebecca Rosenke, Kent Barbian, Kimberly Meade-White, Atsushi Okumura, Shanna Leventhal, David W. Hawman, Emily Ricotta, Catharine M. Bosio, Craig Martens, Greg Saturday, Heinz Feldmann, Michael A. Jarvis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
While vaccines protecting against SARS-CoV-2 infection are approved, currently, there are no drugs suitable for high-risk exposure use against SARS-CoV-2. Here, Rosenke et al. provide evidence that orally delivered MK-4482, a nucleoside analog, inhib
Externí odkaz:
https://doaj.org/article/9a78a63a312847aa863ae1016f4d581a
Autor:
Kyle Rosenke, Friederike Feldmann, Atsushi Okumura, Frederick Hansen, Tsing-Lee Tang-Huau, Kimberly Meade-White, Benjamin Kaza, Julie Callison, Matthew C. Lewis, Brian J. Smith, Patrick W. Hanley, Jamie Lovaglio, Michael A. Jarvis, Carl Shaia, Heinz Feldmann
Publikováno v:
Emerging Microbes and Infections, Vol 10, Iss 1, Pp 2173-2182 (2021)
The continuing emergence of SARS-CoV-2 variants calls for regular assessment to identify differences in viral replication, shedding and associated disease. In this study, we compared African green monkeys infected intranasally with either the UK B.1.
Externí odkaz:
https://doaj.org/article/8c4cfecdfb7f4ce6b472dcefa93fa95e
Autor:
Kyle Rosenke, Kimberly Meade-White, Michael Letko, Chad Clancy, Frederick Hansen, Yanan Liu, Atsushi Okumura, Tsing-Lee Tang-Huau, Rong Li, Greg Saturday, Friederike Feldmann, Dana Scott, Zhongde Wang, Vincent Munster, Michael A. Jarvis, Heinz Feldmann
Publikováno v:
Emerging Microbes and Infections, Vol 9, Iss 1, Pp 2673-2684 (2020)
ABSTRACTFollowing emergence in late 2019, SARS-CoV-2 rapidly became pandemic and is presently responsible for millions of infections and hundreds of thousands of deaths worldwide. There is currently no approved vaccine to halt the spread of SARS-CoV-
Externí odkaz:
https://doaj.org/article/1d3a1172619941ccb2d744b570a4f3f8
Autor:
Zujie Yan, Xiaohui Yao, Ruyi Pan, Junjie Zhang, Xiaochun Ma, Nihua Dong, Jianchao Wei, Ke Liu, Yafeng Qiu, Katie Sealey, Hester Nichols, Michael A. Jarvis, Mathew Upton, Xiangdong Li, Zhiyong Ma, Juxiang Liu, Beibei Li
Publikováno v:
Veterinary Sciences, Vol 10, Iss 1, p 48 (2023)
Streptococcus suis is a significant pathogen in pigs and a newly emerging zoonotic agent in humans. The presence of multiple serotypes and strains with diversified sequence types in pig herds highlights the need for the identification of broadly cros
Externí odkaz:
https://doaj.org/article/7ef7a13483ca451aae9de92ccb6b44c1