Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Michael A. Ischay"'
Autor:
Michael A. Ischay, Brittanie Hoang, Dietrich P. Steinhuebel, Matthew R. Chin, Darryl D. Dixon, Danielle Elfgren, Lars Heumann, Willard Lew, Devon A. Mundal, Sean T. Neville, Nisha P. Shah, Bing Shi, Jonathan C. Tripp, Queenie Wang
Publikováno v:
Organic Process Research & Development. 26:2694-2706
Autor:
Adam B. Weinstein, Michael A. Ischay, Edward M. Doerffler, Nolan D. Griggs, Greg T. Cizio, Matthew M. Logan, Lok Him Lawrence Yu, Baldip S. Kang, Dao Kathy, Patricia D. MacLeod
Publikováno v:
Organic Process Research & Development. 26:745-753
Non-alcoholic steatohepatitis (NASH) is a serious chronic liver disease characterized by progressive fibrosis that can lead to cirrhosis, liver failure, and death. Compound 1 is a farnesoid X recep...
Publikováno v:
Synthesis. 45:2699-2705
We have developed a photocatalytic reduction of nitroarenes as an efficient, chemoselective route to biologically important N-phenyl hydroxamic acid scaffolds. Optimal conditions call for 2.5 mol% of a ruthenium photocatalyst, visible light irradiati
Publikováno v:
Journal of the American Chemical Society. 135:2478-2481
Acid treatment of densely substituted 2-silyl-1,2-dihydropyridines provides a new and convenient entry to reactive azomethine ylides that can (1) be protonated and reduced with high stereoselectivity to give piperidines, (2) participate in [3 + 2] di
Autor:
Michael A. Ischay, Tehshik P. Yoon
Publikováno v:
European Journal of Organic Chemistry. 2012:3359-3372
Organic reactions involving radical cation and radical anion intermediates are synthetically powerful umpolung processes that enable electronically mismatched couplings between pairs of electron-rich or pairs of electron-poor organic fragments. Never
Publikováno v:
Journal of the American Chemical Society. 133:19350-19353
Ruthenium(II) polypyridyl complexes promote the efficient radical cation Diels-Alder cycloaddition of electron-rich dienophiles upon irradiation with visible light. These reactions enable facile [4 + 2] cycloadditions that would be electronically mis
Publikováno v:
Nature Chemistry. 2:527-532
Light can be considered an ideal reagent for environmentally friendly, 'green' chemical synthesis; unlike many conventional reagents, light is non-toxic, generates no waste, and can be obtained from renewable sources. Nevertheless, the need for high-
Publikováno v:
Journal of the American Chemical Society. 130:6610-6615
N-Sulfonyl oxaziridines are susceptible to electrophilic activation using copper(II) catalysts and react with styrenes under these conditions to provide 1,3-oxazolidines in a formal aminohydroxylation of the alkene. We propose a two-step mechanism in
Publikováno v:
European Journal of Organic Chemistry. 2007:5346-5352
Cyclic voltammetry and controlled-potential electrolysis were employed to study the catalytic reduction of five phenyl-conjugated haloalkynes by nickel(I) salen electrogenerated at carbon cathodes in dimethylformamide containing tetramethylammonium t
Autor:
Theodore B. Jennermann, Matthew P. Foley, Mohammad S. Mubarak, Michael A. Ischay, Dennis G. Peters, Philipp W. Raess, Krishnan Raghavachari
Publikováno v:
Journal of Electroanalytical Chemistry. 603:124-134
In dimethylformamide containing tetramethylammonium tetrafluoroborate, 1-iodooctane is reduced catalytically by nickel(I) salen electrogenerated at a glassy carbon cathode. Cyclic voltammograms for the nickel(II) salen–1-iodooctane system recorded