Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Michael A. Gaffield"'
Publikováno v:
eLife, Vol 11 (2022)
The cerebellum is hypothesized to represent timing information important for organizing salient motor events during periodically performed discontinuous movements. To provide functional evidence validating this idea, we measured and manipulated Purki
Externí odkaz:
https://doaj.org/article/8b4f057b358447fe8cb8643939ea62df
Publikováno v:
The Journal of Neuroscience. 43:601-612
Procedural memories formed in the cerebellum in response to motor errors depend on changes to Purkinje cell (PC) spiking patterns that correct movement when the erroneous context is repeated. Because molecular layer interneurons (MLIs) inhibit PCs, l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::619317e9485867da4ec656ccc17aa883
https://doi.org/10.1523/jneurosci.0731-22.2022
https://doi.org/10.1523/jneurosci.0731-22.2022
Publikováno v:
eLife, Vol 7 (2018)
Motor learning involves neural circuit modifications in the cerebellar cortex, likely through re-weighting of parallel fiber inputs onto Purkinje cells (PCs). Climbing fibers instruct these synaptic modifications when they excite PCs in conjunction w
Externí odkaz:
https://doaj.org/article/f939885e8b6644f88526190d9d3d688c
Autor:
Samantha B Amat, Matthew J M Rowan, Michael A Gaffield, Audrey Bonnan, Chikako Kikuchi, Hiroki Taniguchi, Jason M Christie
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179347 (2017)
The cerebellar system helps modulate and fine-tune motor action. Purkinje cells (PCs) provide the sole output of the cerebellar cortex, therefore, any cerebellar involvement in motor activity must be driven by changes in PC firing rates. Several diff
Externí odkaz:
https://doaj.org/article/5a5971fc0bb9471b9ba326a726830076
Autor:
Michael A. Gaffield, Christie Jm
The cerebellum is hypothesized to represent timing information important for organizing salient motor events during periodically performed discontinuous movements. To provide functional evidence validating this idea, we measured and manipulated Purki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3015366f6d55b82d5df05d6cecbcefd
https://doi.org/10.1101/2021.06.24.449622
https://doi.org/10.1101/2021.06.24.449622
Publikováno v:
eLife. 11
The cerebellum is hypothesized to represent timing information important for organizing salient motor events during periodically performed discontinuous movements. To provide functional evidence validating this idea, we measured and manipulated Purki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b14d8975c19539836f0ba70e5cfb43f
https://pubmed.ncbi.nlm.nih.gov/35451957
https://pubmed.ncbi.nlm.nih.gov/35451957
Publikováno v:
Neuron
Summary The brain must make sense of external stimuli to generate relevant behavior. We used a combination of in vivo approaches to investigate how the cerebellum processes sensory-related information. We found that the inferior olive encodes context
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a46d361429ecf00c53e4495cace2bd
https://europepmc.org/articles/PMC6533163/
https://europepmc.org/articles/PMC6533163/
Publikováno v:
Journal of Neurophysiology. 115:413-422
Purkinje cells (PCs) are a major site of information integration and plasticity in the cerebellum, a brain region involved in motor task refinement. Thus PCs provide an ideal location for studying the mechanisms necessary for cerebellum-dependent mot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21c31e8602c969e35e1ec81d20337d1
https://doi.org/10.1152/jn.00834.2015
https://doi.org/10.1152/jn.00834.2015
Autor:
Michael A. Gaffield, Jason M. Christie
The brain must make sense of external stimuli to generate relevant behavior. We used a combination of in vivo approaches to investigate how the cerebellum processes sensory-related information. We found that the inferior olive encodes contexts of sen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0935f90a9e4f65490a3f66daefb36c6c