Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Michael A. Eldarov"'
Publikováno v:
Biomeditsinskaya Khimiya. 66:105-123
L-asparaginase is extensively used in the treatment of acute lymphoblastic leukemia and several other lymphoproliferative diseases. In addition to its biomedical application, L-asparaginase is also of prospective use in food industry to reduce the fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e54226110a008d68495210614910c88
https://doi.org/10.18097/pbmc20206602105
https://doi.org/10.18097/pbmc20206602105
Autor:
A. A. Zhgun, Nikolay N. Sokolov, M. V. Pokrovskaya, Dmitry D. Zhdanov, S. S. Aleksandrova, M. V. Dumina, Michael A. Eldarov
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9894, p 9894 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 18
International Journal of Molecular Sciences
Volume 22
Issue 18
L-asparaginase (L-ASNase) is a vital enzyme with a broad range of applications in medicine and food industry. Drawbacks of current commercial L-ASNases stimulate the search for better-producing sources of the enzyme, and extremophiles are especially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::340bfa6aea6b8cfce720920676165c9c
https://www.mdpi.com/1422-0067/22/18/9894
https://www.mdpi.com/1422-0067/22/18/9894
Autor:
I. S. Kargov, Vladimir I. Tishkov, A.V. Stepashkina, V. V. Fedorchuk, M. D. Shelomov, P. D. Parshin, Francesco Secundo, E. D’Oronzo, K. M. Boiko, S. Facheris, Michael A. Eldarov, S. A. Zarubina, S. S. Savin, R. P. Kovalevski, A. A. Pometun, D. L. Atroshenko
Publikováno v:
Moscow University chemistry bulletin 73 (2018): 70–77. doi:10.3103/S0027131418020153
info:cnr-pdr/source/autori:Tishkov V.I.; Pometun A.A.; Stepashkina A.V.; Fedorchuk V.V.; Zarubina S.A.; Kargov I.S.; Atroshenko D.L.; Parshin P.D.; Shelomov M.D.; Kovalevski R.P.; Boiko K.M.; Eldarov M.A.; D'Oronzo E.; Facheris S.; Secundo F.; Savin S.S./titolo:Rational Design of Practically Important Enzymes/doi:10.3103%2FS0027131418020153/rivista:Moscow University chemistry bulletin/anno:2018/pagina_da:70/pagina_a:77/intervallo_pagine:70–77/volume:73
info:cnr-pdr/source/autori:Tishkov V.I.; Pometun A.A.; Stepashkina A.V.; Fedorchuk V.V.; Zarubina S.A.; Kargov I.S.; Atroshenko D.L.; Parshin P.D.; Shelomov M.D.; Kovalevski R.P.; Boiko K.M.; Eldarov M.A.; D'Oronzo E.; Facheris S.; Secundo F.; Savin S.S./titolo:Rational Design of Practically Important Enzymes/doi:10.3103%2FS0027131418020153/rivista:Moscow University chemistry bulletin/anno:2018/pagina_da:70/pagina_a:77/intervallo_pagine:70–77/volume:73
Majority of native enzymes are poorly applicable for practical usage: that is why different methods of enzyme modification are used to obtain the biocatalysts with appropriate characteristics. Development of genome sequencing and various modern appro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d7b49225f1596434c566d90c93d6673
https://doi.org/10.3103/s0027131418020153
https://doi.org/10.3103/s0027131418020153
Autor:
Marina V. Serebryakova, Vladimir A. Mitkevich, Michael A. Eldarov, K.V. Barinova, Elena V. Schmalhausen, Alexandra A. Kulikova, Vladimir I. Muronetz
Publikováno v:
Biochimica et biophysica acta. General subjects. 1864(6)
Background We previously showed that glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is S-glutathionylated in the presence of H2O2 and GSH. S-glutathionylation was shown to result in the formation of a disulfide bridge in the active site of the prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070c96e6c57f0bc553c5d8a7fc977d17
https://pubmed.ncbi.nlm.nih.gov/32061786
https://pubmed.ncbi.nlm.nih.gov/32061786
Autor:
O. V. Podobed, Alexander I. Archakov, M. V. Pokrovskaya, N. S. Melik-Nubarov, Michael A. Eldarov, S. S. Aleksandrova, Nikolay N. Sokolov, Elena V. Kudryashova, D. V. Grishin, O. Yu. Abakumova
Publikováno v:
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 9:325-338
For more than 40 years L-asparaginases are used in combined therapy of acute lymphoblastic leukemia in children and the range of tumors sensitive to these enzymes constantly extends. This review summarizes results of studies aimed at creation of new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b85e089aeea31667105176253c15366
https://doi.org/10.1134/s199075081504006x
https://doi.org/10.1134/s199075081504006x
Autor:
Vladimir I. Muronetz, Elena V. Schmalhausen, Michael A. Eldarov, Evgeniya Khomyakova, K.V. Barinova
Publikováno v:
Protein expression and purification. 137
The goal of the present work was expression of human glyceraldehyde-3-phosphate dehydrogenase (hGAPDH) without additional tag constructions in E. coli cells and elaboration of the procedure for purification of untagged hGAPDH from the extract of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f82062112da436ee54311c95ddec00fe
https://pubmed.ncbi.nlm.nih.gov/28625912
https://pubmed.ncbi.nlm.nih.gov/28625912
Autor:
M. V. Dumina, A. G. Domracheva, M. I. Novak, Dmitry A. Knorre, A. A. Zhgun, A. Ya. Valiachmetov, Fedor F. Severin, Michael A. Eldarov, I. V. Kerpichnikov, Yu. E. Bartoshevich
Publikováno v:
Applied Biochemistry and Microbiology. 49:368-377
Vectors for the expression of MFS transporter CefT of Acremonium chrysogenum—a producer of beta-lactam antibiotic cephalosporin C—and in Saccharomyces cerevisiae as a fusion with the cyan fluorescent protein (CFP) have been generated. The subcell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf796c8e394ebf6b8dbc6788a65213f7
https://doi.org/10.1134/s0003683813040042
https://doi.org/10.1134/s0003683813040042
Autor:
Michael Taliansky, Michael A. Eldarov, Konstantin G. Skryabin, Eva C. Thuenemann, Paolo Lenzi, Nikolai V. Ravin, Gergana Zahmanova, Ivan Minkov, Ann E. Meyers, Slavica Matić, George P. Lomonossoff, Edward P. Rybicki, Martina Becares, Andrew J. Love, Sonia Zuñiga, Alta Hattingh, Emanuela Noris, Luis Enjuanes, Oleg I. Kiselev
Publikováno v:
Current Pharmaceutical Design
Advances in transient expression technologies have allowed the production of milligram quantities of proteins within a matter of days using only small amounts (tens of grams) of plant tissue. Among the proteins that have been produced using this appr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67fd33c982a327a162690e8bca4b3597
Publikováno v:
Molecular Biology. 46:279-286
Human β2-adrenergic receptor is among the most studied members of the family of G-protein coupled receptors. This receptor plays an important role in the work of vegetative nervous system and is a target for drugs used in heart and lung diseases. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1bfa5851366ef8116ae57f01b3fb68a
https://doi.org/10.1134/s0026893312020057
https://doi.org/10.1134/s0026893312020057
Autor:
Andrey V. Mardanov, Nikolai V. Ravin, Michael A. Eldarov, Konstantin G. Skryabin, V. V. Dzhavakhiya, Alexey V. Beletsky
Publikováno v:
FEMS Microbiology Letters. 329:9-17
We determined the complete mitochondrial genome sequence of the compactin-producing fungus Penicillium solitum strain 20-01. The 28 601-base pair circular-mapping DNA molecule encodes a characteristic set of mitochondrial proteins and RNA genes and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9023317ea41642a31e8b7af66efb306b
https://doi.org/10.1111/j.1574-6968.2012.02497.x
https://doi.org/10.1111/j.1574-6968.2012.02497.x