Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Michael A. Eissenstat"'
Autor:
Elena Chertova, Michael A. Eissenstat, José R. Casas-Finet, Connor Mcgrath, Louis E. Henderson, Igor A. Topol, Stanley K. Burt, Catherine O. Dasenbrock, William R. LaCourse
Publikováno v:
Protein Science. 10:1434-1445
A diverse set of electrophilic compounds that react with cysteine thiolates in retroviral nucleocapsid (NC) proteins and abolish virus infectivity has been identified. Although different in chemical composition, these compounds are all oxidizing agen
Publikováno v:
Current Opinion in HIV and AIDS. 3:633-641
This review describes current approaches to HIV protease inhibitor design, with a focus on improving their profile against drug-resistant mutants. Potential explanations for the flat resistance profile of some potent protease inhibitors and discrepan
Publikováno v:
The Journal of Physical Chemistry A. 104:9619-9624
Using a combination of ab initio, DFT and continuum solvation methods, the gas phase and aqueous acidities for a set of weak organic acids with high pKa values, which cannot be measured experimentally in aqueous solvent, have been calculated. Compari
Autor:
Sherman F. Stinson, David J. Clanton, Tyra House, Betty Yu, T. Narayana Bhat, John W. Erickson, Ramnarayan S. Randad, Michael A. Eissenstat, Lucyna Lubkowska, Sergei V. Gulnik
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 8:3537-3542
A series of novel unsymmetrical anthranilamide-containing HIV protease inhibitors was designed. The structure-activity studies revealed a series of potent P2–P3′ inhibitors that incorporate an anthranilamide group at the P2′ position. A reducti
Autor:
Sherman F. Stinson, David J. Clanton, Lucyna Lubkowska, T. Narayana Bhat, Betty Yu, Sergei V. Gulnik, Michael A. Eissenstat, Ramnarayan S. Randad, Tyra House, John W. Erickson
Publikováno v:
ChemInform. 30
A series of novel unsymmetrical anthranilamide-containing HIV protease inhibitors was designed. The structure-activity studies revealed a series of potent P2–P3′ inhibitors that incorporate an anthranilamide group at the P2′ position. A reducti
Publikováno v:
American Peptide Symposia ISBN: 0792351606
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ff1bf6fb7b623b1ddcd12714fbc680b
https://doi.org/10.1007/0-306-46862-x_135
https://doi.org/10.1007/0-306-46862-x_135
Publikováno v:
Journal of the American Chemical Society. 101:2196-2198
Autor:
Paul A. Wender, Michael A. Eissenstat
Publikováno v:
Journal of the American Chemical Society. 100:292-294
Autor:
Michael A. Eissenstat, Paul A. Wender
Publikováno v:
Chemischer Informationsdienst. 9
Das Isomerisierungsprodukt des a, -ungesattigten Imins (I), das Alkenylimin (II), wird mit tBu-Li [analog mit sBu-Li, nBu-Li, Ph-Li] zu dem Lithioenamin (III) metalliert, dessen Umsetzung in situ mit den Alkylhalogeniden (IV) und anschliesende saure