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pro vyhledávání: '"Michael A. Castello"'
Publikováno v:
Pediatric Quality & Safety
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Background: Written patient handoffs are susceptible to errors or incompleteness. The accuracy is dependent on the person inputting the information. Thus, handoff printouts generated by elec
Background: Written patient handoffs are susceptible to errors or incompleteness. The accuracy is dependent on the person inputting the information. Thus, handoff printouts generated by elec
Autor:
Michael A. Castello, Joseph G. Gleeson
Publikováno v:
Current opinion in neurobiology. 66
Cortical development involves neurogenesis followed by migration, maturation, and myelination of immature neurons. Disruptions in these processes can cause malformations of cortical development (MCD). Radial glia (RG) are the stem cells of the brain,
Publikováno v:
Advances in Alzheimer's Disease. :137-144
To date, therapies to prevent or treat Alzheimer’s disease (AD) have largely focused on removing excess aggregation-prone amyloid peptide Aβ from the brain, an approach that has produced disappointing clinical outcomes. An alternative hypothesis p
Autor:
Michael A. Castello, Salvador Soriano
Publikováno v:
Ageing Research Reviews. 12(1):282-288
According to the amyloid cascade hypothesis, accumulation of the amyloid peptide Aβ, derived by proteolytic processing from the amyloid precursor protein (APP), is the key pathogenic trigger in Alzheimer's disease (AD). This view has led researchers
Autor:
Loren P. Thompson, Tamara Blutstein, Michael A. Castello, Maria M. Hadjimarkou, Mary K. Holder, Joseph A. McQuail, Jessica A. Mong, Shaun S. Viechweg
Publikováno v:
Neurotoxicity Research. 24:80-93
In utero exposure to cigarette smoke has severe consequences for the developing fetus, including increased risk of birth complications and behavioral and learning disabilities later in life. Evidence from animal models suggests that the cognitive def
Publikováno v:
BMC Neurology
Background: High-profile Phase 3 clinical trials of bapineuzumab and solanezumab, antibodies targeted at amyloid-beta (Aβ) removal, have failed to meet their primary endpoints. Neit her drug improves clinical outcomes in patients with late onset AD,
Autor:
Asmita Modak, Michael G. Castello, Shih-Chieh Jeff Chueh, Edwin J. Avallone, Lorie Lipscomb, Bashir R. Sankari
Publikováno v:
ASAIO journal (American Society for Artificial Internal Organs : 1992). 60(1)
Benefits of pulsatile machine perfusion (pumping) of standard criteria donor (SCD) kidneys are unclear. Our center is located 4½ hours from our Organ Procurement Organization. We evaluated outcomes of pumping SCD kidneys under such circumstances by
Autor:
Michael A. Castello, Salvador Soriano
Publikováno v:
Ageing research reviews. 13
The amyloid cascade hypothesis, which implicates the amyloid Aβ peptide as the pathological initiator of both familial and sporadic, late onset Alzheimer's disease (AD), continues to guide the majority of research. We believe that current evidence d
Publikováno v:
Alzheimer's & Dementia. 9
Publikováno v:
Journal of Urology. 189