Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Michael A. Cannarile"'
Autor:
Michael A. Cannarile, Martin Weisser, Wolfgang Jacob, Anna-Maria Jegg, Carola H. Ries, Dominik Rüttinger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 5, Iss 1, Pp 1-13 (2017)
Abstract The tumor-permissive and immunosuppressive characteristics of tumor-associated macrophages (TAM) have fueled interest in therapeutically targeting these cells. In this context, the colony-stimulating factor 1 (CSF1)/colony-stimulating factor
Externí odkaz:
https://doaj.org/article/d178a458f1254b0b92d2840ec5a6df0e
Autor:
Cláudia S Ferreira, Konstanty Korski, Michael A Cannarile, Irina Klaman, Petra C Schwalie, Iakov I Davydov, Andreas Roller, Martha L Serrano-Serrano, Astrid Heller, Nicolas Staedler, Gabriele Dietmann, Alberto Valdeolivas
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background The immune status of a patient’s tumor microenvironment (TME) may guide therapeutic interventions with cancer immunotherapy and help identify potential resistance mechanisms. Currently, patients’ immune status is mostly classified base
Externí odkaz:
https://doaj.org/article/a65b392cfd034dc18fbbd68b9a6b32bf
Autor:
Ena Wang, Alessandra Cesano, Beatrix Kotlan, Mohan Karkada, Nicholas Tschernia, Aung Naing, Bruno Gomes, Anne Monette, Vésteinn Thórsson, Sergio Rutella, Vaios Karanikas, Michael A Cannarile, Justin Guinney, Giuseppe V Masucci, Els Meeusen, Daniel K Wells, Timothy L Wyant
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
The development of strongly predictive validated biomarkers is essential for the field of immuno-oncology (IO) to advance. The highly complex, multifactorial data sets required to develop these biomarkers necessitate effective, responsible data-shari
Externí odkaz:
https://doaj.org/article/093f0e8ec32a4d008042f3b582974250
Autor:
Meghna Das, Thakur, Carl J, Franz, Laura, Brennan, Jurriaan, Brouwer-Visser, Rachel, Tam, Konstanty, Korski, Hartmut, Koeppen, James, Ziai, Galina, Babitzki, Dominique, Ranchere-Vince, Alexandre, Vasiljevic, Frédérique, Dijoud, Perrine, Marec-Bérard, Isabelle, Rochet, Michael A, Cannarile, Aurélien, Marabelle
Publikováno v:
European Journal of Cancer. 170:179-193
The clinical development of immune checkpoint-targeted immunotherapies has been disappointing so far in paediatric solid tumours. However, as opposed to adults, very little is known about the immune contexture of paediatric malignancies.We investigat
Autor:
Carola H. Ries, Dominik Rüttinger, Hadassah Sade, Michael A. Cannarile, Solange Romagnoli, Chia-Huey Ooi, Leon P. Pradel
Correlation of certain epidemiological factors to a large donor cohort treated with RG7155
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5db1881dbf3c1f41a2705200290d63
https://doi.org/10.1158/1535-7163.22507959.v1
https://doi.org/10.1158/1535-7163.22507959.v1
Autor:
Carola H. Ries, Dominik Rüttinger, Hadassah Sade, Michael A. Cannarile, Solange Romagnoli, Chia-Huey Ooi, Leon P. Pradel
Additional details on primary human and cynomolgus material handling, RNA and DNA based assay design as well as SPR experimentation setup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ebdc489a50c0cf92175ab8d938aebff
https://doi.org/10.1158/1535-7163.22507944
https://doi.org/10.1158/1535-7163.22507944
Autor:
Carola H. Ries, Dominik Rüttinger, Hadassah Sade, Michael A. Cannarile, Solange Romagnoli, Chia-Huey Ooi, Leon P. Pradel
Information on primer sequences and conditions used for subsequent RT-PCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d337dcbd18f41ed693420370a57778
https://doi.org/10.1158/1535-7163.22507941
https://doi.org/10.1158/1535-7163.22507941
Autor:
Jehad Charo, Allyson L. Byrd, Bernhard Reis, Mahesh Yadav, Bruno Gomes, Vaios Karanikas, Marta Cañamero, Michael A. Cannarile
Publikováno v:
Clinical Cancer Research. 27:4147-4159
Today, there is a huge effort to develop cancer immunotherapeutics capable of combating cancer cells as well as the biological environment in which they can grow, adapt, and survive. For such treatments to benefit more patients, there is a great need
Autor:
Kristy L. Weber, Randolph Christen, Keelara Abiraj, Anna-Maria Jegg, Maud Toulmonde, Delphine Loirat, Martin Weisser, Irina Klaman, Michael A. Cannarile, Carlos Gomez-Roca, Jean-Yves Blay, Wolfgang Jacob, Antoine Italiano, Carl Watson, Francesca Michielin, Philippe A. Cassier, Jean-Pierre Delord, Dominik Rüttinger, Christophe Le Tourneau, Carola Ries, Sandra P. D'Angelo
Publikováno v:
European Journal of Cancer. 141:162-170
Objectives This study investigated the safety, clinical activity and patient-reported outcomes of patients with diffuse-type tenosynovial giant-cell tumour (dTGCT) of the soft tissue who were treated with emactuzumab, a humanised anti-colony stimulat
Autor:
Carlos Gomez-Roca, Philippe Cassier, Dmitriy Zamarin, Jean-Pascal Machiels, Jose Luis Perez Gracia, F Stephen Hodi, Alvaro Taus, Maria Martinez Garcia, Valentina Boni, Joseph P Eder, Navid Hafez, Ryan Sullivan, David Mcdermott, Stephane Champiat, Sandrine Aspeslagh, Catherine Terret, Anna-Maria Jegg, Wolfgang Jacob, Michael A Cannarile, Carola Ries, Konstanty Korski, Francesca Michielin, Randolph Christen, Galina Babitzki, Carl Watson, Georgina Meneses-Lorente, Martin Weisser, Dominik Rüttinger, Jean-Pierre Delord, Aurelien Marabelle
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol. 10, no.5, p. e004076 (2022)
BackgroundThis phase 1b study (NCT02323191) evaluated the safety, antitumor activity, pharmacokinetics, and pharmacodynamics of colony-stimulating factor-1 receptor-blocking monoclonal antibody (mAb) emactuzumab in combination with the programmed cel