Zobrazeno 1 - 10
of 576
pro vyhledávání: '"Michael A. Hast"'
Autor:
Bon-hyeock Koo, Yeon-Ju Lee, Na Rae Park, Su Chin Heo, David M. Hudson, Aysel A. Fernandes, Chet S. Friday, Michael W. Hast, David T. Corr, Douglas R. Keene, Sara F. Tufa, Nathaniel A. Dyment, Kyu Sang Joeng
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The biological mechanisms regulating tenocyte differentiation and morphological maturation have not been well-established, partly due to the lack of reliable in vitro systems that produce highly aligned collagenous tissues. In this study, we
Externí odkaz:
https://doaj.org/article/cce7e84906324ac18d089ea546ee2e81
Publikováno v:
Toxins, Vol 16, Iss 8, p 366 (2024)
Chronic sialorrhea is a condition characterized by excessive drooling, often associated with neurological and neuromuscular disorders such as Parkinson’s disease, cerebral palsy, and stroke. Despite its prevalence, it remains underdiagnosed and poo
Externí odkaz:
https://doaj.org/article/9a0662c58be64b7a89416d68685c1a07
Publikováno v:
Toxins, Vol 16, Iss 8, p 362 (2024)
Movement disorders such as cervical dystonia, blepharospasm, and hemifacial spasm negatively impact the quality of life of people living with these conditions. Botulinum toxin (BoNT) injections are commonly used to treat these disorders. We sought to
Externí odkaz:
https://doaj.org/article/c50b151cc9de4da18c26a2555c36747c
Autor:
Jessica Llewellyn, Caterina Fede, Abigail E. Loneker, Chet S. Friday, Michael W. Hast, Neil D. Theise, Emma E. Furth, Maria Guido, Carla Stecco, Rebecca G. Wells
Publikováno v:
JHEP Reports, Vol 5, Iss 9, Pp 100760- (2023)
Background & Aims: Glisson’s capsule is the interstitial connective tissue that surrounds the liver. As part of its normal physiology, it withstands significant daily changes in liver size. The pathophysiology of the capsule in disease is not well
Externí odkaz:
https://doaj.org/article/f72ca49d744e4847ab46882bd3e9e617
Autor:
Vaida Glatt, PhD, Robert O'Toole, MD, Samir Mehta, MD, Utku Kandemir, MD, William Ricci, MD, Aaron Nauth, MD, Emil Schemitsch, MD, Michael W. Hast, PhD
Publikováno v:
OTA International, Vol 6, Iss 2S (2023)
Summary:. At the 2021 annual meeting of the Orthopaedic Trauma Association, the Basic Science Focus Forum hosted its first ever debate-style symposium focused on biomechanics and fracture repair. The 3 subjects of debate were “Mechanics versus Biol
Externí odkaz:
https://doaj.org/article/b9feb72553a14616a7a7d2cc3e199a35
Autor:
Wolfgang H. Jost, Petr Kaňovský, Michael A. Hast, Angelika Hanschmann, Michael Althaus, Atul T. Patel
Publikováno v:
Toxins, Vol 15, Iss 6, p 353 (2023)
The pooled incidences of treatment-emergent adverse events (TEAEs) were examined by indication using the integrated clinical database of Merz-sponsored, placebo-controlled, or repeat-dose studies of incobotulinumtoxinA in adults with cervical dystoni
Externí odkaz:
https://doaj.org/article/4808435d9442408e993c0b3626073ad2
Autor:
Michael R. Eby, Danielle M. Cristino, Matthew Counihan, Kendall M. Masada, Jaimo Ahn, Michael W. Hast
Publikováno v:
BMC Musculoskeletal Disorders, Vol 22, Iss 1, Pp 1-9 (2021)
Abstract Background Failure of surgical fixation in orthopaedic fractures occurs at a significantly higher rate in osteoporotic patients due to weakened osteoporotic bone. A therapy to acutely improve the mechanical properties of bone during fracture
Externí odkaz:
https://doaj.org/article/beb07ded97cd4563843f47664e601208
Autor:
Elaine C. Schmidt, MS, Lauren M. Judkins, BS, Guha Manogharan, PhD, Samir Mehta, MD, Michael W. Hast, PhD
Publikováno v:
OTA International, Vol 5, Iss 1S, p e164 (2022)
Abstract. Objectives:. Current surgical fracture treatment paradigms, which use rigid metallic constructs to heal bones, provide reasonable clinical outcomes; however, they do not leverage recent advances in our understanding of bone healing and mech
Externí odkaz:
https://doaj.org/article/3ab49d1c2c3b4125a4f737356fcfad7f
Publikováno v:
Foot & Ankle Orthopaedics, Vol 7 (2022)
Category: Sports; Basic Sciences/Biologics Introduction/Purpose: Achilles tendon disorders are among the most common conditions observed by sports medicine physicians and among the most difficult to diagnose using current clinical tools. While qualit
Externí odkaz:
https://doaj.org/article/62fadfe7291a4e1db694adc4b52451b0
Autor:
Cynthia Comella, Robert A. Hauser, Stuart H. Isaacson, Daniel Truong, Odinachi Oguh, Jennifer Hui, Eric S. Molho, Matthew Brodsky, Erin Furr-Stimming, Georg Comes, Michael A. Hast, David Charles
Publikováno v:
Clinical Parkinsonism & Related Disorders, Vol 6, Iss , Pp 100142- (2022)
IntroductionSome patients with cervical dystonia (CD) receiving long-term botulinum neurotoxin (BoNT) therapy report early waning of treatment benefit before the typical 12-week reinjection interval. Methods: This phase 4, open-label, randomized, non
Externí odkaz:
https://doaj.org/article/3fa867ffb3694c2dbb3fcc82e13d78bd