Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Michael A Laflamme"'
Autor:
Nikki Gillum Posnack, Rabia Idrees, Hao Ding, Rafael Jaimes, Gulnaz Stybayeva, Zaruhi Karabekian, Michael A Laflamme, Narine Sarvazyan
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121927 (2015)
BackgroundThe pervasive nature of plastics has raised concerns about the impact of continuous exposure to plastic additives on human health. Of particular concern is the use of phthalates in the production of flexible polyvinyl chloride (PVC) product
Externí odkaz:
https://doaj.org/article/a87b7c8bcf7840309c535869f1c9e3d8
Autor:
Fanny Wulkan, Rocco Romagnuolo, Beiping Qiang, Tamilla Valdman Sadikov, Kyung-Phil Kim, Elya Quesnel, Wenlei Jiang, Naaz Andharia, Jill J. Weyers, Nilesh R. Ghugre, Bilgehan Ozcan, Faisal J. Alibhai, Michael A. Laflamme
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
BackgroundHuman pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) show tremendous promise for cardiac regeneration following myocardial infarction (MI), but their transplantation gives rise to transient ventricular tachycardia (VT) in large-ani
Externí odkaz:
https://doaj.org/article/0c3a1bff478443819665f3585f74ddc7
Autor:
Ena Ray Banerjee, Michael A Laflamme, Thalia Papayannopoulou, Michael Kahn, Charles E Murry, William R Henderson
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33165 (2012)
Our aim was to differentiate human (h) embryonic stem (ES) cells into lung epithelial lineage-specific cells [i.e., alveolar epithelial type I (AEI) and type II (AEII) cells and Clara cells] as the first step in the development of cell-based strategi
Externí odkaz:
https://doaj.org/article/b7684b37f16243c9aa0ad3c5067f927e
Autor:
Jay A Gantz, Nathan J Palpant, Robert E Welikson, Stephen D Hauschka, Charles E Murry, Michael A Laflamme
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46971 (2012)
The differentiation of pluripotent stem cells involves transition through a series of specific cell states. To understand these cell fate decisions, the field needs improved genetic tools for the labeling, lineage tracing and selection of specific ce
Externí odkaz:
https://doaj.org/article/f9d56ffe70674db7a8231b3e54a8e37d
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5407 (2009)
We investigated the mechanisms of excitation-contraction (EC) coupling in human embryonic stem cell-derived cardiomyocytes (hESC-CMs) and fetal ventricular myocytes (hFVMs) using patch-clamp electrophysiology and confocal microscopy. We tested the hy
Externí odkaz:
https://doaj.org/article/f5195646e0304fa5926a5066fd85914d
Autor:
Dawn Bannerman, Simon Pascual-Gil, Scott Campbell, Richard Jiang, Qinghua Wu, Sargol Okhovatian, Karl T. Wagner, Miles Montgomery, Michael A. Laflamme, Locke Davenport Huyer, Milica Radisic
Publikováno v:
Materials Today Bio, Vol 24, Iss , Pp 100917- (2024)
Application of cardiac patches to the heart surface can be undertaken to provide support and facilitate regeneration of the damaged cardiac tissue following ischemic injury. Biomaterial composition is an important consideration in the design of cardi
Externí odkaz:
https://doaj.org/article/dd570fc40a124a18a7021ccc78830642
Autor:
Rasha Al-attar, Joseph Jargstorf, Rocco Romagnuolo, Mariam Jouni, Faisal J. Alibhai, Paul D. Lampe, Joell L. Solan, Michael A. Laflamme
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 61 (2024)
The transplantation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) has shown promise in preclinical models of myocardial infarction, but graft myocardium exhibits incomplete host–graft electromechanical integration and a propensit
Externí odkaz:
https://doaj.org/article/78cf26346a0b476b8ceddafac10f4217
Autor:
Peter Lee, Luqia Hou, Faisal J. Alibhai, Rasha Al-attar, Ana Simón-Chica, Andrés Redondo-Rodríguez, Yilin Nie, Maria Mirotsou, Michael A. Laflamme, Gayathri Swaminath, David Filgueiras-Rama
Publikováno v:
Frontiers in Cardiovascular Medicine. 10
Scalable and high-throughput electrophysiological measurement systems are necessary to accelerate the elucidation of cardiac diseases in drug development. Optical mapping is the primary method of simultaneously measuring several key electrophysiologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::511bc192c2262f22dc267d626fd6d9fb
Autor:
Wahiba Dhahri, Tamilla Sadikov Valdman, Dan Wilkinson, Elizabeth Pereira, Eylül Ceylan, Naaz Andharia, Beiping Qiang, Hassan Masoudpour, Fanny Wulkan, Elya Quesnel, Wenlei Jiang, Shunsuke Funakoshi, Amine Mazine, M. Juliana Gomez-Garcia, Neda Latifi, Yidi Jiang, Ella Huszti, Craig A. Simmons, Gordon Keller, Michael A. Laflamme
Publikováno v:
Circulation
Background: Human pluripotent stem cell (hPSC)–derived cardiomyocytes (hPSC-CMs) have tremendous promise for application in cardiac regeneration, but their translational potential is limited by an immature phenotype. We hypothesized that large-scal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d62ab5c4f7e0d9d31c18f26824aa728
https://doi.org/10.1161/circulationaha.121.053563
https://doi.org/10.1161/circulationaha.121.053563
Publikováno v:
Stem Cells International, Vol 2017 (2017)
Human pluripotent stem cells derived cardiomyocytes (PSC-CMs) have been widely used for disease modeling, drug safety screening, and preclinical cell therapy to regenerate myocardium. Most studies have utilized PSC-CM grown in vitro for a relatively
Externí odkaz:
https://doaj.org/article/f512aa1509de4709ad70a39b9d16dd6b