Zobrazeno 1 - 10
of 546
pro vyhledávání: '"Michael A Carpenter"'
Autor:
Michael A Carpenter, Nuri A Temiz, Mahmoud A Ibrahim, Matthew C Jarvis, Margaret R Brown, Prokopios P Argyris, William L Brown, Gabriel J Starrett, Douglas Yee, Reuben S Harris
Publikováno v:
PLoS Genetics, Vol 19, Iss 11, p e1011043 (2023)
A prominent source of mutation in cancer is single-stranded DNA cytosine deamination by cellular APOBEC3 enzymes, which results in signature C-to-T and C-to-G mutations in TCA and TCT motifs. Although multiple enzymes have been implicated, reports co
Externí odkaz:
https://doaj.org/article/7dba9a036fc5426d8eef1ae0a701054d
Autor:
Pieter A Roelofs, Chai Yeen Goh, Boon Haow Chua, Matthew C Jarvis, Teneale A Stewart, Jennifer L McCann, Rebecca M McDougle, Michael A Carpenter, John WM Martens, Paul N Span, Dennis Kappei, Reuben S Harris
Publikováno v:
eLife, Vol 9 (2020)
APOBEC3B (A3B)-catalyzed DNA cytosine deamination contributes to the overall mutational landscape in breast cancer. Molecular mechanisms responsible for A3B upregulation in cancer are poorly understood. Here we show that a single E2F cis-element medi
Externí odkaz:
https://doaj.org/article/562661be3bbb4115a4d955575847fc12
Autor:
Monica K Akre, Gabriel J Starrett, Jelmar S Quist, Nuri A Temiz, Michael A Carpenter, Andrew N J Tutt, Anita Grigoriadis, Reuben S Harris
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155391 (2016)
Molecular, cellular, and clinical studies have combined to demonstrate a contribution from the DNA cytosine deaminase APOBEC3B (A3B) to the overall mutation load in breast, head/neck, lung, bladder, cervical, ovarian, and other cancer types. However,
Externí odkaz:
https://doaj.org/article/024cee0f0d1b4bec89920db5c73cfb22
Autor:
Mads C. Weber, Mael Guennou, Donald M. Evans, Constance Toulouse, Arkadiy Simonov, Yevheniia Kholina, Xiaoxuan Ma, Wei Ren, Shixun Cao, Michael A. Carpenter, Brahim Dkhil, Manfred Fiebig, Jens Kreisel
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-7 (2022)
Typically, magnetic phenomena result from the spontaneous order of the sublattices. Here, the cross-talk of two magnetic ions gives rise to an intrinsic, yet non-spontaneous ordering and manifests as emergent strong spin–phonon coupling in SmFeO3.
Externí odkaz:
https://doaj.org/article/6a043c8f6c944d3bab7964f4bf7f9401
Autor:
Katherine F. M. Jones, Mohamed Shehata, Michael A. Carpenter, Rommie E. Amaro, Daniel A. Harki
Publikováno v:
ACS Medicinal Chemistry Letters. 14:338-343
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9227d70b7d5a316238389046c0dcceda
https://doi.org/10.1021/acsmedchemlett.2c00517
https://doi.org/10.1021/acsmedchemlett.2c00517
Autor:
Diako Ebrahimi, Christopher M. Richards, Michael A. Carpenter, Jiayi Wang, Terumasa Ikeda, Jordan T. Becker, Adam Z. Cheng, Jennifer L. McCann, Nadine M. Shaban, Daniel J. Salamango, Gabriel J. Starrett, Jairam R. Lingappa, Jeongsik Yong, William L. Brown, Reuben S. Harris
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Human APOBEC3H has several haplotypes and splice variants with distinct anti-HIV-1 activities, but the genetics underlying the expression of these variants are unclear. Here, the authors identify an intronic deletion in A3H haplotype II resulting in
Externí odkaz:
https://doaj.org/article/ea3b48a2ed974a7c8e6b38190a93470e
Publikováno v:
Physical Review B. 107
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff43885a5e8e45f4f86abab8e934ecad
https://doi.org/10.1103/physrevb.107.144108
https://doi.org/10.1103/physrevb.107.144108
Autor:
Reuben S. Harris, Scott H. Kaufmann, Hugues Sicotte, Ellen L. Goode, Kimberly R. Kalli, Lynn C. Hartmann, Elizabeth M. Swisher, Jeremy Chien, John Peden, Zoya Kingsbury, Sean Humphray, Russell Grocock, Jian-Bing Fan, R. Keira Cheetham, Marina Bibikova, David Bentley, Craig April, Debra A. Bell, Viji Shridhar, Julie M. Cunningham, Ann L. Oberg, Matthew J. Maurer, Yuji Zhang, Ying Li, William L. Brown, Emily K. Law, Jason B. Nikas, Rachel I. Vogel, Anurag Rathore, Nuri A. Temiz, Michael A. Carpenter, Michael B. Burns, Steven N. Hart, Brandon Leonard
PDF file - 481K, Table S1: Cell line information Table S2: Quantitative PCR primer and probe sequences. Table S3: Non-malignant tissues tested Table S4: Early stage serous ovarian tumors used in sequence analyses Table S5: Additional ovarian tumor sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257df24e001a06c97dcee7ba0d83e354
https://doi.org/10.1158/0008-5472.22396406.v1
https://doi.org/10.1158/0008-5472.22396406.v1
Autor:
Terumasa Ikeda, Ryo Shimizu, Hesham Nasser, Michael A. Carpenter, Adam Z. Cheng, William L. Brown, Daniel Sauter, Reuben S. Harris
Publikováno v:
bioRxiv
HIV-1 must overcome multiple innate antiviral mechanisms to replicate in CD4+T lymphocytes and macrophages. Previous studies have demonstrated that the APOBEC3 (A3) family of proteins (at least A3D, A3F, A3G, and stable A3H haplotypes) contribute to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59e2cf3a90d1d31ff45f2426bfb3d293
https://europepmc.org/articles/PMC10081227/
https://europepmc.org/articles/PMC10081227/
Autor:
Heng Tang, Özlem Demir, Fredy Kurniawan, William L. Brown, Ke Shi, Nicholas H. Moeller, Michael A. Carpenter, Christopher Belica, Kayo Orellana, Guocheng Du, Aaron M. LeBeau, Rommie E. Amaro, Reuben S. Harris, Hideki Aihara
Publikováno v:
Viruses, Vol 13, Iss 4, p 663 (2021)
APOBEC3B (A3B) is one of seven human APOBEC3 DNA cytosine deaminases that restrict viral infections as part of the overall innate immune response, but it also plays a major role in tumor evolution by mutating genomic DNA. Given the importance of A3B
Externí odkaz:
https://doaj.org/article/3daf921745df4152a82909b42ca58aea