Zobrazeno 1 - 10
of 542
pro vyhledávání: '"Michael A Bender"'
Autor:
Jianliang Xu, Tongqing Zhou, Krisha McKee, Baoshan Zhang, Cuiping Liu, Alexandra F. Nazzari, Amarendra Pegu, Chen‐Hsiang Shen, Jordan E. Becker, Michael F. Bender, Payton Chan, Anita Changela, Ridhi Chaudhary, Xuejun Chen, Tal Einav, Young Do Kwon, Bob C. Lin, Mark K. Louder, Jonah S. Merriam, Nicholas C. Morano, Sijy O'Dell, Adam S. Olia, Reda Rawi, Ryan S. Roark, Tyler Stephens, I‐Ting Teng, Emily Tourtellott‐Fogt, Shuishu Wang, Eun Sung Yang, Lawrence Shapiro, Yaroslav Tsybovsky, Nicole A. Doria‐Rose, Rafael Casellas, Peter D. Kwong
Publikováno v:
Advanced Science, Vol 11, Iss 26, Pp n/a-n/a (2024)
Abstract Broadly neutralizing antibodies are proposed as therapeutic and prophylactic agents against HIV‐1, but their potency and breadth are less than optimal. This study describes the immunization of a llama with the prefusion‐stabilized HIV‐
Externí odkaz:
https://doaj.org/article/2af27b428ce0453586e0f60b99fd2446
Autor:
Young D. Kwon, Amarendra Pegu, Eun Sung Yang, Baoshan Zhang, Michael F. Bender, Mangaiarkarasi Asokan, Qingbo Liu, Krisha McKee, Bob C. Lin, Tracy Liu, Mark K. Louder, Reda Rawi, Mateo Reveiz, Andrew J. Schaub, Chen-Hsiang Shen, Nicole A. Doria-Rose, Paolo Lusso, John R. Mascola, Peter D. Kwong
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTThe amino-acid composition of the immunoglobulin variable region has been observed to impact antibody pharmacokinetics (PK). Here, we sought to improve the PK of the broad HIV−1-neutralizing VRC01-class antibodies, VRC07-523LS and N6LS, by
Externí odkaz:
https://doaj.org/article/404c6bcba63e47658183c99f62376df3
Autor:
Baoshan Zhang, Jason Gorman, Young D. Kwon, Amarendra Pegu, Cara W. Chao, Tracy Liu, Mangaiarkarasi Asokan, Michael F. Bender, Tatsiana Bylund, Leland Damron, Deepika Gollapudi, Paula Lei, Yile Li, Cuiping Liu, Mark K. Louder, Krisha McKee, Adam S. Olia, Reda Rawi, Arne Schön, Shuishu Wang, Eun Sung Yang, Yongping Yang, Kevin Carlton, Nicole A. Doria-Rose, Lawrence Shapiro, Michael S. Seaman, John R. Mascola, Peter D. Kwong
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTAntibody CAP256-VRC26.25 targets the second hypervariable region (V2) at the apex of the HIV envelope (Env) trimer with extraordinary neutralization potency, although less than optimal breadth. To improve breadth, we linked the light chain of
Externí odkaz:
https://doaj.org/article/bddbe9ec6f5b4b779bcbe4b49830cab8
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
While valuable chemicals can be obtained from biomass electro-oxidation, the mechanisms can be challenging to discern. Here, authors show that explicit control of electrochemical dehydrogenation mechanisms enables selective secondary alcohol oxidatio
Externí odkaz:
https://doaj.org/article/5babc0fec54746bc911db1e8693bf001
Publikováno v:
Frontiers in Sports and Active Living, Vol 4 (2022)
Acute and chronic hydration status is important for athlete safety and performance and is frequently measured by sports scientists and performance staff in team environments via urinalysis. However, the time required for urine collection, staff testi
Externí odkaz:
https://doaj.org/article/5bcefcaae6da43e7bc7d48978c926d86
Autor:
Ashish Rai, Anna P. Chang, Steven Soo, Joy Thomas, Judy Ackerman, Brian Mitzman, Michael T. Bender
Publikováno v:
Critical Care Innovations, Vol 3, Iss 3, Pp 13-19 (2020)
INTRODUCTION: SARS-CoV-2 is a novel strain of coronavirus that has caused illness in over 6 million people worldwide as of June 2020. Patients with severe illness are treated with invasive mechanical ventilation, as such, tracheostomy has become a to
Externí odkaz:
https://doaj.org/article/d72d80309ffa4cb19b281d88c2162205
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-4 (2020)
(Photo)electrochemical cells that produce fuels have often relied on water oxidation to complete the redox cycle. Here, the authors discuss alcohol oxidation as an alternative reaction and consider general mechanistic features of oxidation electrocat
Externí odkaz:
https://doaj.org/article/c5f510d9893d490383f8124b88e24173
Autor:
Vikas Chonira, Young D. Kwon, Jason Gorman, James Brett Case, Zhiqiang Ku, Rudo Simeon, Ryan G. Casner, Darcy R. Harris, Adam S. Olia, Tyler Stephens, Lawrence Shapiro, Michael F. Bender, Hannah Boyd, I-Ting Teng, Yaroslav Tsybovsky, Florian Krammer, Ningyan Zhang, Michael S. Diamond, Peter D. Kwong, Zhiqiang An, Zhilei Chen
Publikováno v:
Nature Chemical Biology. 19:284-291
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8545c90f585b6702d4b4bb248bf97f4c
https://doi.org/10.1038/s41589-022-01193-2
https://doi.org/10.1038/s41589-022-01193-2
Autor:
Michael A. Bender, Mary Hulihan, Mary Christine Dorley, Maria del Pilar Aguinaga, Jelili Ojodu, Careema Yusuf
Publikováno v:
International Journal of Neonatal Screening, Vol 7, Iss 4, p 83 (2021)
Beta-thalassemia, a heritable condition of abnormal hemoglobin production, is not a core condition on the United States Recommended Uniform Screening Panel (RUSP) for state and territorial newborn screening (NBS) programs. However, screening for sick
Externí odkaz:
https://doaj.org/article/3f046655ab924e789dc2e5a3c836ce89
Publikováno v:
ACS Catalysis. 12:12349-12368
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73ffa208fea473a675dca732b12b3d8c
https://doi.org/10.1021/acscatal.2c03606
https://doi.org/10.1021/acscatal.2c03606