Zobrazeno 1 - 10 of 64 pro vyhledávání: '"Michael A Augello"'
1
Akademický článek
Canonical androgen response element motifs are tumor suppressive regulatory elements in the prostate
Autor: Xuanrong Chen, Michael A. Augello, Deli Liu, Kevin Lin, Alex Hakansson, Martin Sjöström, Francesca Khani, Lesa D. Deonarine, Yang Liu, Jaida Travascio-Green, Jiansheng Wu, Un In Chan, Jude Owiredu, Massimo Loda, Felix Y. Feng, Brian D. Robinson, Elai Davicioni, Andrea Sboner, Christopher E. Barbieri
Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The androgen receptor (AR) is central in prostate tissue identity and differentiation, and controls normal growth-suppressive, prostate-specific gene expression. It also drives prostate tumorigenesis when hijacked for oncogenic transcription
Externí odkaz: https://doaj.org/article/07a68e6011a946bc9d120ecc4b67fc67
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2
Akademický článek
Consequence of the tumor‐associated conversion to cyclin D1b
Autor: Michael A Augello, Lisa D Berman‐Booty, Richard Carr, Akihiro Yoshida, Jeffry L Dean, Matthew J Schiewer, Felix Y Feng, Scott A Tomlins, Erhe Gao, Walter J Koch, Jeffrey L Benovic, John Alan Diehl, Karen E Knudsen
Publikováno v: EMBO Molecular Medicine, Vol 7, Iss 5, Pp 628-647 (2015)
Abstract Clinical evidence suggests that cyclin D1b, a variant of cyclin D1, is associated with tumor progression and poor outcome. However, the underlying molecular basis was unknown. Here, novel models were created to generate a genetic switch from
Externí odkaz: https://doaj.org/article/c0a939ceeb9240749fd9c3c0d5d3e22e
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Plný text Recenzováno Digitální knihovna AV ČR
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