Zobrazeno 1 - 10
of 3 379
pro vyhledávání: '"Michael A, Taylor"'
Autor:
Kandarp Joshi, Menglang Yuan, Keisuke Katsushima, Olivier Saulnier, Animesh Ray, Ernest Amankwah, Stacie Stapleton, George Jallo, Michael D. Taylor, Charles G. Eberhart, Ranjan J. Perera
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-14 (2024)
Abstract Medulloblastoma, the most common malignant pediatric brain tumor, is classified into four main molecular subgroups, but group 3 and group 4 tumors are difficult to subclassify and have a poor prognosis. Rapid point-of-care diagnostic and pro
Externí odkaz:
https://doaj.org/article/326f988b197f4347bf4fff9b3108c6a0
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103260- (2024)
Summary: Cancer stem cells (CSCs) established from surgical biopsies closely mimic the human context and can be used to investigate disease mechanisms, genetic fitness, and therapeutic evaluation. Here, we present a protocol for the derivation of pri
Externí odkaz:
https://doaj.org/article/1bc5101bac0443238e48891b18b50ee4
Autor:
Deron O. Maitland, Kristin Richter, Roshin P. Raj, Antonio Bonaduce, Kerim H. Nisancioglu, Michael A. Taylor, Tannecia S. Stephenson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Tropical Small Island Developing States (SIDS), such as those in the Caribbean, are among the most vulnerable to the impacts of climate change, most notably sea-level rise. The current sea-level rise in the Caribbean is 3.40 ± 0.3 mm/year (
Externí odkaz:
https://doaj.org/article/571d0ca625e74e3bb673825952b7b0aa
Autor:
Catherine Min, Jean-Philippe Galons, Ronald M. Lynch, Leah V. Steyn, Nicholas D. Price, Brad P. Weegman, Michael J. Taylor, Abhishek Pandey, Robert Harland, Diego Martin, David Besselsen, Charles W. Putnam, Klearchos K. Papas
Publikováno v:
Frontiers in Transplantation, Vol 3 (2024)
IntroductionTransplantation of kidneys from expanded criteria donors (ECD), including after circulatory death (DCD), is associated with a higher risk of adverse events compared to kidneys from standard criteria donors. In previous studies, improvemen
Externí odkaz:
https://doaj.org/article/5ecff4219fa1444483f23269e6180e51
Autor:
Beatrice L. Gordon, Gabrielle F. S. Boisrame, Rosemary W. H. Carroll, Newsha K. Ajami, Bryan Leonard, Christine Albano, Naoki Mizukami, Manuel A. Andrade, Elizabeth Koebele, Michael H. Taylor, Adrian A. Harpold
Publikováno v:
Earth's Future, Vol 12, Iss 6, Pp n/a-n/a (2024)
Abstract Climate change‐induced shifts in snow storage and snowmelt patterns pose risks for adverse impacts to people, the environment, and irrigated agriculture. Existing research primarily focuses on evaluating these risks to irrigated agricultur
Externí odkaz:
https://doaj.org/article/ff5999bf75b540ac890ee9ca2cfed164
Autor:
Benjamin Draper, Chantelle Bowers, Eleni Vassalou, Ailsa Greppi, John Anderson, Nabil Ahmed, Michael D. Taylor, Laura K. Donovan
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 103078- (2024)
Summary: Here, we present a protocol for preclinical evaluation of locoregionally delivered CAR T cells in patient-derived xenograft models of primary, metastatic, and recurrent brain tumors. We provide instructions for isolating peripheral blood mon
Externí odkaz:
https://doaj.org/article/dc2222e4f824449c93ce23541c00e4e0
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-31 (2024)
Abstract Existing RNA velocity estimation methods strongly rely on predefined dynamics and cell-agnostic constant transcriptional kinetic rates, assumptions often violated in complex and heterogeneous single-cell RNA sequencing (scRNA-seq) data. Usin
Externí odkaz:
https://doaj.org/article/6cf53315e61f4c3ea3e7ec45154ee2dc
Autor:
Maxwell P. Gold, Winnie Ong, Andrew M. Masteller, David R. Ghasemi, Julie Anne Galindo, Noel R. Park, Nhan C. Huynh, Aneesh Donde, Veronika Pister, Raul A. Saurez, Maria C. Vladoiu, Grace H. Hwang, Tanja Eisemann, Laura K. Donovan, Adam D. Walker, Joseph Benetatos, Christelle Dufour, Livia Garzia, Rosalind A. Segal, Robert J. Wechsler-Reya, Jill P. Mesirov, Andrey Korshunov, Kristian W. Pajtler, Scott L. Pomeroy, Olivier Ayrault, Shawn M. Davidson, Jennifer A. Cotter, Michael D. Taylor, Ernest Fraenkel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Many genes that drive normal cellular development also contribute to oncogenesis. Medulloblastoma (MB) tumors likely arise from neuronal progenitors in the cerebellum, and we hypothesized that the heterogeneity observed in MBs with sonic hed
Externí odkaz:
https://doaj.org/article/7e7b389f322c4aed99ee994b5589418d
Autor:
Menglang Yuan, Iqbal Mahmud, Keisuke Katsushima, Kandarp Joshi, Olivier Saulnier, Rudramani Pokhrel, Bongyong Lee, Wathsala Liyanage, Haritha Kunhiraman, Stacie Stapleton, Ignacio Gonzalez-Gomez, Rangaramanujam M. Kannan, Tanja Eisemann, Elayaraja Kolanthai, Sudipta Seal, Timothy J. Garrett, Saed Abbasi, Kimberly Bockley, Justin Hanes, Prem Chapagain, George Jallo, Robert J. Wechsler-Reya, Michael D. Taylor, Charles G. Eberhart, Animesh Ray, Ranjan J. Perera
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-17 (2023)
Abstract The prognosis of childhood medulloblastoma (MB) is often poor, and it usually requires aggressive therapy that adversely affects quality of life. microRNA-211 (miR-211) was previously identified as an important regulator of cells that descen
Externí odkaz:
https://doaj.org/article/d02fc40d411f4baba42e490fbec01155
Autor:
MICHAEL P. TAYLOR, MATHEW J. WEDEL
Publikováno v:
Acta Palaeontologica Polonica, Vol 68, Iss 4, Pp 709-718 (2023)
Pneumatic dorsal ribs are known for many sauropods, but to date costal pneumaticity has received relatively little attention. In particular, the pneumatic ribs of the holotype specimen of Brachiosaurus altithorax have been largely overlooked, altho
Externí odkaz:
https://doaj.org/article/8858c311b90440bb85223e13d869cea3