Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Michael A, Pacanowski"'
Autor:
Christine Lee, Joseph S Ross, Molly Moore Jeffery, Nilay D Shah, David B Page, Nancy Chang, Fernanda Bellolio, Sam Torbati, Jessica D Ritchie, Gregg H Gilbert, Lindsay Emanuel, Mitra Ahadpour, Summer Allen, Richardae Araojo, Laura Ciaccio, Jonathan Fillmore, Patricia Koussis, Heather Lipkind, Celeste Mallama, Tamra Meyer, Megan Moncur, Teryl Nuckols, Michael A Pacanowski, Elektra Papadopoulos, Mat Soukup, Christopher O St. Clair, Stephen Tamang, Douglas W Wallace, Yueqin Zhao, Rebekah Heckmann
Publikováno v:
BMJ Open, Vol 12, Iss 7 (2022)
Introduction Opioid analgesics are often used to treat moderate-to-severe acute non-cancer pain; however, there is little high-quality evidence to guide clinician prescribing. An essential element to developing evidence-based guidelines is a better u
Externí odkaz:
https://doaj.org/article/ac2ab0b35e6d4d258418cef239bf7638
Autor:
Greg Welder, Issam Zineh, Michael A. Pacanowski, Jason S. Troutt, Guoqing Cao, Robert J. Konrad
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 9, Pp 2714-2721 (2010)
Proprotein convertase subtilisin kexin type 9 (PCSK9) is a key regulator of serum LDL-cholesterol (LDL-C) levels. PCSK9 is secreted by the liver into the plasma and binds the hepatic LDL receptor (LDLR), causing its subsequent degradation. We first d
Externí odkaz:
https://doaj.org/article/187324920d8f4dae8a837d81e9a01ab5
Autor:
Molly Moore Jeffery, Mitra Ahadpour, Summer Allen, Richardae Araojo, Fernanda Bellolio, Nancy Chang, Laura Ciaccio, Lindsay Emanuel, Jonathan Fillmore, Gregg H Gilbert, Patricia Koussis, Christine Lee, Heather Lipkind, Celeste Mallama, Tamra Meyer, Megan Moncur, Teryl Nuckols, Michael A Pacanowski, David B Page, Elektra Papadopoulos, Jessica D Ritchie, Joseph S Ross, Nilay D Shah, Mat Soukup, Christopher O St. Clair, Stephen Tamang, Sam Torbati, Douglas W Wallace, Yueqin Zhao, Rebekah Heckmann
Publikováno v:
BMJ Open. 12:e058782
IntroductionOpioid analgesics are often used to treat moderate-to-severe acute non-cancer pain; however, there is little high-quality evidence to guide clinician prescribing. An essential element to developing evidence-based guidelines is a better un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5677dcc756c13cec1deac4bfd43002f5
https://doi.org/10.1136/bmjopen-2021-058782
https://doi.org/10.1136/bmjopen-2021-058782
Publikováno v:
JACC: Basic to Translational Science
Summary The U.S. Food and Drug Administration recently marked 10 years since first updating the labeling for warfarin (often referred to as the “poster child” of pharmacogenomics) to include information regarding the potential impact of CYP2C9 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b5e7fbc5c8cd5f75ce31e5e5cbe1c544
https://pubmed.ncbi.nlm.nih.gov/30175278
https://pubmed.ncbi.nlm.nih.gov/30175278
Autor:
Richard B, Horenstein, Rajnikanth, Madabushi, Issam, Zineh, Laura M, Yerges-Armstrong, Cody J, Peer, Robert N, Schuck, William Douglas, Figg, Alan R, Shuldiner, Michael A, Pacanowski
Publikováno v:
Journal of clinical pharmacology. 54(8)
Carriers of two copies of the loss-of-function CYP2C19*2 variant convert less clopidogrel into its active metabolite, resulting in diminished antiplatelet responses and higher cardiovascular event rates. To evaluate whether increasing the daily clopi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bddf1e856e8125cfa9c9f4c4fab93233
https://pubmed.ncbi.nlm.nih.gov/24710841
https://pubmed.ncbi.nlm.nih.gov/24710841
Publikováno v:
The New England journal of medicine. 368(23)
In response to reports of respiratory depression and death in young children who had received codeine after tonsillectomy, adenoidectomy, or both, the FDA initiated a safety evaluation. The result is a boxed warning on the labels of all codeine-conta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04369e094cf875cbce4b70b09ee56df3
https://pubmed.ncbi.nlm.nih.gov/23614474
https://pubmed.ncbi.nlm.nih.gov/23614474
Autor:
Michael A Pacanowski, Guy W. Amsden
Publikováno v:
The Annals of pharmacotherapy. 39(10)
Objective: To examine the clinical aspects of idiopathic pulmonary fibrosis (IPF) and the efficacy and safety of interferon gamma-1b (IFNγ−1b) in its treatment. Data Sources: Epidemiologic, preclinical, and clinical studies published in the Englis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40323be8d712fb67bfbff10e5e22c361
https://pubmed.ncbi.nlm.nih.gov/16160001
https://pubmed.ncbi.nlm.nih.gov/16160001