Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Michael A, Lampson"'
Autor:
Tomohiro Kumon, Michael A. Lampson
Publikováno v:
Seminars in Cell & Developmental Biology. 128:51-60
Despite the universal requirement for faithful chromosome segregation, eukaryotic centromeres are rapidly evolving. It is hypothesized that rapid centromere evolution represents an evolutionary arms race between selfish genetic elements that drive, o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df48a66cd67bc37f0b2f82cefeb7864a
https://doi.org/10.1016/j.semcdb.2022.03.026
https://doi.org/10.1016/j.semcdb.2022.03.026
Autor:
Arunika Das, Katelyn G. Boese, Kikue Tachibana, Sung Hee Baek, Michael A. Lampson, Ben E. Black
Publikováno v:
bioRxiv
SUMMARYCentromeres direct genetic inheritance but are not themselves genetically encoded. Instead, centromeres are defined epigenetically by the presence of a histone H3 variant, CENP-A1. In cultured somatic cells, an established paradigm of cell cyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9949284aa7f80acd42275a04db39b730
https://europepmc.org/articles/PMC10245701/
https://europepmc.org/articles/PMC10245701/
Autor:
Craig W. Gambogi, Nootan Pandey, Jennine M. Dawicki-McKenna, Uma P. Arora, Mikhail A. Liskovykh, Jun Ma, Piero Lamelza, Vladimir Larionov, Michael A. Lampson, Glennis A. Logsdon, Beth L. Dumont, Ben E. Black
Mammalian centromeres direct faithful genetic inheritance and are typically characterized by regions of highly repetitive and rapidly evolving DNA. We focused on a mouse species,Mus pahari,that we found has evolved to house centromere-specifying CENP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::582ad18a1d2c2319a1385e6ac4e1ea76
https://doi.org/10.1101/2023.05.11.540353
https://doi.org/10.1101/2023.05.11.540353
Autor:
Brandon H. Hayes, Peter Kuangzheng Zhu, Mai Wang, Charlotte R. Pfeifer, Yuntao Xia, Steven Phan, Jason C. Andrechak, Junhong Du, Michael P. Tobin, Alisya Anlas, Lawrence J. Dooling, Manasvita Vashisth, Jerome Irianto, Michael A. Lampson, Dennis E. Discher
Publikováno v:
Journal of Cell Science.
A cell's mechanical environment can have many effects, but whether it impacts a cell's DNA sequence has remained unclear. To investigate this, we developed a live-cell method to measure changes in chromosome numbers. We edited constitutive genes with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5356d9a2def24255ced16711a66b819
https://doi.org/10.1242/jcs.260753
https://doi.org/10.1242/jcs.260753
Cell biologists typically focus on conserved regions of a protein, overlooking innovations that can shape its function over evolutionary time. Computational analyses can reveal potential innovations by detecting statistical signatures of positive sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11b9c5ce773a500629e4cada0e4308e5
https://doi.org/10.1101/2023.02.27.530329
https://doi.org/10.1101/2023.02.27.530329
Autor:
Brandon H Hayes, Peter Kuangzheng Zhu, Mai Wang, Charlotte R Pfeifer, Yuntao Xia, Steven Phan, Jason C Andrechak, Junhong Du, Michael P Tobin, Alisya Anlas, Lawrence Dooling, Manasvita Vashisth, Jerome Irianto, Michael A. Lampson, Dennis E Discher
Matrix around cells exerts many effects, some of which depend on the putative tumor suppressor Myosin-II, but whether such factors affect DNA sequences in a cell remains unclear. Here, live-cell monitoring of changes to chromosome copy numbers is dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a43bba16d4157aa501f4d0ab23445cf
https://doi.org/10.1101/2023.02.25.530049
https://doi.org/10.1101/2023.02.25.530049
Autor:
Gabriel Manske, Kelsey Jorgensen, Binbin Ma, Mansour Aboelenain, Catherine Tower, Saikat Chakraborty, Rajesh Ranjan, Arunika Das, Michael A. Lampson, Ben E. Black, Karen Schindler, Xin Chen, Saher Sue Hammoud
SummaryThe CENP-A histone variant epigenetically defines centromeres, where its levels and locations are precisely maintained through mitotic cell divisions. However, differences in centromere CENP-A propagation in soma versus female/male germline re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16d4f09032a7e608a7becfb709dbf400
https://doi.org/10.1101/2022.10.27.514094
https://doi.org/10.1101/2022.10.27.514094
Autor:
Michael A. Lampson, Geng-Yuan Chen
Publikováno v:
Nat Chem Biol
Components of the cell division machinery typically function at varying cell cycle stages and intracellular locations. To dissect cellular mechanisms during the rapid division process, small-molecule probes act as complementary approaches to genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f2ef4bf82663795594a4140304094d
https://doi.org/10.1038/s41589-021-00798-3
https://doi.org/10.1038/s41589-021-00798-3
Autor:
Nootan Pandey, Craig Gambogi, Jennine Dawicki‐McKenna, Uma Arora, Glennis Logsdon, Jun Ma, Piero Lamelza, Michael A. Lampson, Beth Dumont, Ben E. Black
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0aad4eeeba5689fc5094aba1959cbef4
https://doi.org/10.1096/fasebj.2022.36.s1.r3575
https://doi.org/10.1096/fasebj.2022.36.s1.r3575
Autor:
Takashi Akera, Michael A Lampson
Publikováno v:
eLife, Vol 5 (2016)
The factors that lead to errors in chromosome segregation during the production of egg cells in humans are becoming clearer.
Externí odkaz:
https://doaj.org/article/5034fe9e2d384581886081362f694285