Zobrazeno 1 - 10
of 285
pro vyhledávání: '"Michael A, Jakupec"'
Autor:
Weerasak Songoen, Dominik Wenisch, Michael A. Jakupec, Witthawat Phanchai, Siriphan Sukkhaeng, Lothar Brecker, Johann Schinnerl, Sorachat Tharamak, Wanchai Pluempanupat
Publikováno v:
ACS Omega, Vol 9, Iss 31, Pp 33888-33899 (2024)
Externí odkaz:
https://doaj.org/article/7b02c438cd264e97872e5132b63d50a1
Autor:
Juliana Ivanova, Rositsa Kukeva, Radostina Stoyanova, Tanya Zhivkova, Abedulkadir Abudalleh, Lora Dyakova, Radostina Alexandrova, Irena Pashkunova-Martic, Johannes Theiner, Peter Dorkov, Michaela Hejl, Michael A. Jakupec, Bernhard Keppler, Ivo Grabchev
Publikováno v:
Inorganics, Vol 12, Iss 8, p 206 (2024)
In this study we demonstrated for the first time synthetic procedures for composites of salinomycin (SalH) and two-line ferrihydrite. The products were characterized by various methods such as elemental analysis, attenuated total reflectance–Fourie
Externí odkaz:
https://doaj.org/article/e1f77c51436d46cb900135f3ca61b5ae
Autor:
Yvonne Lerchbammer-Kreith, Michaela Hejl, Dominik Wenisch, Michael A. Jakupec, Mathea S. Galanski, Bernhard K. Keppler
Publikováno v:
Inorganics, Vol 11, Iss 10, p 411 (2023)
A series of thirty novel tetracarboxylatoplatinum(IV) complexes in trans-configuration featuring combinations of mixed ammine, methylamine, dimethylamine, and cyclopentylamine ligands as well as acetato/propanoato and trifluoropropanoato ligands was
Externí odkaz:
https://doaj.org/article/6093e1aff91a4d12af737a1628b50509
Autor:
Yvonne Lerchbammer-Kreith, Michaela Hejl, Nadine S. Sommerfeld, Xian Weng-Jiang, Uchechukwu Odunze, Ryan D. Mellor, David G. Workman, Michael A. Jakupec, Andreas G. Schätzlein, Ijeoma F. Uchegbu, Mathea S. Galanski, Bernhard K. Keppler
Publikováno v:
Pharmaceuticals, Vol 16, Iss 7, p 1027 (2023)
Quaternary ammonium palmitoyl glycol chitosan (GCPQ) has already shown beneficial drug delivery properties and has been studied as a carrier for anticancer agents. Consequently, we synthesised cytotoxic platinum(IV) conjugates of cisplatin, carboplat
Externí odkaz:
https://doaj.org/article/b83c0dfc255c45309374a06652151faa
Autor:
Klaudia Cseh, Iker Berasaluce, Valentin Fuchs, Alexandra Banc, Andreas Schweikert, Alexander Prado-Roller, Michaela Hejl, Debora Wernitznig, Gunda Koellensperger, Michael A. Jakupec, Wolfgang Kandioller, Michael S. Malarek, Bernhard K. Keppler
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1875 (2023)
The synthesis, characterization and biological activity of tungstenocenes with varying biologically active (O,O–), (S,O–) and (N,O–) chelates are described. Complexes were characterized by 1H and 13C NMR, elemental analysis, ESI-mass spectromet
Externí odkaz:
https://doaj.org/article/ea3cf9f74c25426fa612f412705e4581
Autor:
Mate Rusz, Giorgia Del Favero, Yasin El Abiead, Christopher Gerner, Bernhard K. Keppler, Michael A. Jakupec, Gunda Koellensperger
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Oxidative stress and reactive oxygen species (ROS) are central to many physiological and pathophysiological processes. However, due to multiple technical challenges, it is hard to capture a comprehensive readout of the cell, involving both b
Externí odkaz:
https://doaj.org/article/50dbdd09112b498cbe5c3a1330ed7682
Autor:
Dr. Heiko Geisler, Dr. Sophia Harringer, Dominik Wenisch, Richard Urban, Dr. Michael A. Jakupec, Dr. Wolfgang Kandioller, Prof. Dr. Dr. Bernhard K. Keppler
Publikováno v:
ChemistryOpen, Vol 11, Iss 7, Pp n/a-n/a (2022)
Abstract The cytotoxicities of seven dimeric metal species of the general formula [M(arene)Cl2]2, commonly used as precursors for complex synthesis and deemed biologically inactive, are investigated in seven commonly employed human cancer cell lines.
Externí odkaz:
https://doaj.org/article/21ca71982a364b418d6fc6e062aede83
Autor:
Yvonne Lerchbammer-Kreith, Michaela Hejl, Petra Vician, Michael A. Jakupec, Walter Berger, Mathea S. Galanski, Bernhard K. Keppler
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1515 (2023)
Based on their drug delivery properties and activity against tumors, we combined PAMAM dendrimers with various platinum(IV) complexes in order to provide an improved approach of anticancer treatment. Platinum(IV) complexes were linked to terminal NH2
Externí odkaz:
https://doaj.org/article/a76602e5e3d84c4bb7a76ae7b269b879
Autor:
Yvonne Lerchbammer-Kreith, Nadine S. Sommerfeld, Klaudia Cseh, Xian Weng-Jiang, Uchechukwu Odunze, Andreas G. Schätzlein, Ijeoma F. Uchegbu, Mathea S. Galanski, Michael A. Jakupec, Bernhard K. Keppler
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1050 (2023)
A new class of anticancer prodrugs was designed by combining the cytotoxicity of platinum(IV) complexes and the drug carrier properties of glycol chitosan polymers: Unsymmetrically carboxylated platinum(IV) analogues of cisplatin, carboplatin and oxa
Externí odkaz:
https://doaj.org/article/2c1521fc3aa645ab91b5d4aefaa51a8a
Autor:
Klaudia Cseh, Heiko Geisler, Kristina Stanojkovska, Julia Westermayr, Philipp Brunmayr, Dominik Wenisch, Natalie Gajic, Michaela Hejl, Martin Schaier, Gunda Koellensperger, Michael A. Jakupec, Philipp Marquetand, Wolfgang Kandioller
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2466 (2022)
The main purpose of this study was to synthesize a new set of naphthoquinone-based ruthenium(II) arene complexes and to develop an understanding of their mode of action. This study systematically reviews the steps of synthesis, aiming to provide a si
Externí odkaz:
https://doaj.org/article/44bade57a6da472699725b6490e5fc1f